(25 nodes) Regulation of protein deacetylation network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	YEATS2	YEATS domain containing 2. (645 aa)
	sirt1	Sirtuin 1. (677 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2573 aa)
	fnta	Farnesyltransferase, CAAX box, alpha. (376 aa)
	kat14	Lysine acetyltransferase 14. (679 aa)
	rrp8	Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family. (496 aa)
	tada2a	Transcriptional adapter. (445 aa)
	sgf29	SAGA complex associated factor 29. (290 aa)
	sdr16c5	Short chain dehydrogenase/reductase family 16C, member 5a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (306 aa)
	mbip	MAP3K12 binding inhibitory protein 1. (334 aa)
	dr1	Down-regulator of transcription 1. (176 aa)
	ENSPREP00000024233	Uncharacterized protein. (102 aa)
	LOC103469771	Zinc finger protein 703. (579 aa)
	LOC103468460	E1A binding protein p300 b. (2737 aa)
	zzz3	Zinc finger, ZZ-type containing 3. (1173 aa)
	LOC103475119	Transforming growth factor beta; Belongs to the TGF-beta family. (380 aa)
	ucn	Urotensin 1. (147 aa)
	sap30bp	SAP30 binding protein. (209 aa)
	LOC103457597	Jun dimerization protein 2. (163 aa)
	brms1	BRMS1 transcriptional repressor and anoikis regulator. (293 aa)
	LOC103482005	E1A binding protein p300 a. (2743 aa)
	TPPP	Tubulin polymerization promoting protein. (220 aa)
	prkaa2	Non-specific serine/threonine protein kinase. (557 aa)
	prkaa1	Non-specific serine/threonine protein kinase. (637 aa)
	pink1	PTEN induced kinase 1. (575 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000024233	YEATS2	ENSPREP00000024233	ENSPREP00000024351	Uncharacterized protein.	YEATS domain containing 2.	0.899
ENSPREP00000024233	dr1	ENSPREP00000024233	ENSPREP00000020589	Uncharacterized protein.	Down-regulator of transcription 1.	0.839
ENSPREP00000024233	kat14	ENSPREP00000024233	ENSPREP00000007647	Uncharacterized protein.	Lysine acetyltransferase 14.	0.924
ENSPREP00000024233	mbip	ENSPREP00000024233	ENSPREP00000020227	Uncharacterized protein.	MAP3K12 binding inhibitory protein 1.	0.822
ENSPREP00000024233	sgf29	ENSPREP00000024233	ENSPREP00000017550	Uncharacterized protein.	SAGA complex associated factor 29.	0.905
ENSPREP00000024233	tada2a	ENSPREP00000024233	ENSPREP00000013600	Uncharacterized protein.	Transcriptional adapter.	0.819
ENSPREP00000024233	zzz3	ENSPREP00000024233	ENSPREP00000026708	Uncharacterized protein.	Zinc finger, ZZ-type containing 3.	0.785
LOC103468460	LOC103475119	ENSPREP00000026558	ENSPREP00000027136	E1A binding protein p300 b.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.523
LOC103468460	LOC103482005	ENSPREP00000026558	ENSPREP00000030842	E1A binding protein p300 b.	E1A binding protein p300 a.	0.902
LOC103468460	sirt1	ENSPREP00000026558	ENSPREP00000003960	E1A binding protein p300 b.	Sirtuin 1.	0.587
LOC103475119	LOC103468460	ENSPREP00000027136	ENSPREP00000026558	Transforming growth factor beta; Belongs to the TGF-beta family.	E1A binding protein p300 b.	0.523
LOC103475119	LOC103482005	ENSPREP00000027136	ENSPREP00000030842	Transforming growth factor beta; Belongs to the TGF-beta family.	E1A binding protein p300 a.	0.523
LOC103482005	LOC103468460	ENSPREP00000030842	ENSPREP00000026558	E1A binding protein p300 a.	E1A binding protein p300 b.	0.902
LOC103482005	LOC103475119	ENSPREP00000030842	ENSPREP00000027136	E1A binding protein p300 a.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.523
LOC103482005	sirt1	ENSPREP00000030842	ENSPREP00000003960	E1A binding protein p300 a.	Sirtuin 1.	0.587
YEATS2	ENSPREP00000024233	ENSPREP00000024351	ENSPREP00000024233	YEATS domain containing 2.	Uncharacterized protein.	0.899
YEATS2	dr1	ENSPREP00000024351	ENSPREP00000020589	YEATS domain containing 2.	Down-regulator of transcription 1.	0.839
YEATS2	kat14	ENSPREP00000024351	ENSPREP00000007647	YEATS domain containing 2.	Lysine acetyltransferase 14.	0.924
YEATS2	mbip	ENSPREP00000024351	ENSPREP00000020227	YEATS domain containing 2.	MAP3K12 binding inhibitory protein 1.	0.822
YEATS2	sgf29	ENSPREP00000024351	ENSPREP00000017550	YEATS domain containing 2.	SAGA complex associated factor 29.	0.905