24 items (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	bag3	BCL2 associated athanogene 3. (516 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2573 aa)
	LOC103469840	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (234 aa)
	itgb1bp1	Integrin beta 1 binding protein 1. (193 aa)
	derl2	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (276 aa)
	cdk5	Cyclin-dependent kinase 5. (262 aa)
	bag4	BCL2 associated athanogene 4. (377 aa)
	clg20h11orf65	Uncharacterized protein. (289 aa)
	bard1	BRCA1 associated RING domain 1. (722 aa)
	LOC103479802	Apolipoprotein Da, duplicate 1; Belongs to the calycin superfamily. Lipocalin family. (186 aa)
	svip	Si:ch73-147o17.1. (80 aa)
	cep131	Centrosomal protein 131. (1215 aa)
	nf1	Neurofibromin 1b. (2742 aa)
	os9	OS9 endoplasmic reticulum lectin. (705 aa)
	LOC103479463	Sirtuin 6. (339 aa)
	rangap1	RAN GTPase activating protein 1a. (575 aa)
	ube2g2	Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast). (154 aa)
	chp1	Calcineurin-like EF-hand protein 1. (154 aa)
	pkig	Protein kinase (cAMP-dependent, catalytic) inhibitor gamma. (127 aa)
	LOC103481999	Ran GTPase activating protein 1b. (567 aa)
	rab23	RAB23, member RAS oncogene family. (204 aa)
	erlec1	Endoplasmic reticulum lectin 1. (498 aa)
	LOC103456761	Apolipoprotein Db; Belongs to the calycin superfamily. Lipocalin family. (182 aa)
	ube2j1	Ubiquitin-conjugating enzyme E2, J1. (275 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103469840	derl2	ENSPREP00000005741	ENSPREP00000009081	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.901
LOC103469840	erlec1	ENSPREP00000005741	ENSPREP00000033924	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Endoplasmic reticulum lectin 1.	0.933
LOC103469840	os9	ENSPREP00000005741	ENSPREP00000025152	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	OS9 endoplasmic reticulum lectin.	0.933
LOC103469840	ube2g2	ENSPREP00000005741	ENSPREP00000027103	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast).	0.440
LOC103469840	ube2j1	ENSPREP00000005741	ENSPREP00000001669	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ubiquitin-conjugating enzyme E2, J1.	0.512
LOC103481999	rangap1	ENSPREP00000030639	ENSPREP00000026307	Ran GTPase activating protein 1b.	RAN GTPase activating protein 1a.	0.902
LOC103481999	ube2j1	ENSPREP00000030639	ENSPREP00000001669	Ran GTPase activating protein 1b.	Ubiquitin-conjugating enzyme E2, J1.	0.537
bag3	bag4	ENSPREP00000003708	ENSPREP00000014073	BCL2 associated athanogene 3.	BCL2 associated athanogene 4.	0.559
bag4	bag3	ENSPREP00000014073	ENSPREP00000003708	BCL2 associated athanogene 4.	BCL2 associated athanogene 3.	0.559
bard1	ube2j1	ENSPREP00000017694	ENSPREP00000001669	BRCA1 associated RING domain 1.	Ubiquitin-conjugating enzyme E2, J1.	0.551
derl2	LOC103469840	ENSPREP00000009081	ENSPREP00000005741	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.901
derl2	erlec1	ENSPREP00000009081	ENSPREP00000033924	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Endoplasmic reticulum lectin 1.	0.933
derl2	os9	ENSPREP00000009081	ENSPREP00000025152	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	OS9 endoplasmic reticulum lectin.	0.943
derl2	ube2g2	ENSPREP00000009081	ENSPREP00000027103	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast).	0.440
derl2	ube2j1	ENSPREP00000009081	ENSPREP00000001669	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ubiquitin-conjugating enzyme E2, J1.	0.512
erlec1	LOC103469840	ENSPREP00000033924	ENSPREP00000005741	Endoplasmic reticulum lectin 1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.933
erlec1	derl2	ENSPREP00000033924	ENSPREP00000009081	Endoplasmic reticulum lectin 1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.933
erlec1	ube2g2	ENSPREP00000033924	ENSPREP00000027103	Endoplasmic reticulum lectin 1.	Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast).	0.478
erlec1	ube2j1	ENSPREP00000033924	ENSPREP00000001669	Endoplasmic reticulum lectin 1.	Ubiquitin-conjugating enzyme E2, J1.	0.579
os9	LOC103469840	ENSPREP00000025152	ENSPREP00000005741	OS9 endoplasmic reticulum lectin.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.933