(7 nodes) Telomeric loop disassembly network (Poecilia reticulata)

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Your Input:
	terf1	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (367 aa)
	terf2	HTH myb-type domain-containing protein. (635 aa)
	pot1	Telo_bind domain-containing protein. (763 aa)
	rtel1	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1180 aa)
	blm	BLM RecQ like helicase. (1399 aa)
	slx4	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1463 aa)
	recql4	RecQ helicase-like 4. (1237 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
blm	pot1	ENSPREP00000011311	ENSPREP00000024452	BLM RecQ like helicase.	Telo_bind domain-containing protein.	0.706
blm	rtel1	ENSPREP00000011311	ENSPREP00000012657	BLM RecQ like helicase.	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	0.783
blm	slx4	ENSPREP00000011311	ENSPREP00000000407	BLM RecQ like helicase.	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae).	0.768
blm	terf1	ENSPREP00000011311	ENSPREP00000026481	BLM RecQ like helicase.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.637
blm	terf2	ENSPREP00000011311	ENSPREP00000018221	BLM RecQ like helicase.	HTH myb-type domain-containing protein.	0.649
pot1	blm	ENSPREP00000024452	ENSPREP00000011311	Telo_bind domain-containing protein.	BLM RecQ like helicase.	0.706
pot1	recql4	ENSPREP00000024452	ENSPREP00000018082	Telo_bind domain-containing protein.	RecQ helicase-like 4.	0.675
pot1	rtel1	ENSPREP00000024452	ENSPREP00000012657	Telo_bind domain-containing protein.	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	0.601
pot1	terf1	ENSPREP00000024452	ENSPREP00000026481	Telo_bind domain-containing protein.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.968
pot1	terf2	ENSPREP00000024452	ENSPREP00000018221	Telo_bind domain-containing protein.	HTH myb-type domain-containing protein.	0.969
recql4	pot1	ENSPREP00000018082	ENSPREP00000024452	RecQ helicase-like 4.	Telo_bind domain-containing protein.	0.675
recql4	rtel1	ENSPREP00000018082	ENSPREP00000012657	RecQ helicase-like 4.	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	0.706
recql4	slx4	ENSPREP00000018082	ENSPREP00000000407	RecQ helicase-like 4.	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae).	0.607
recql4	terf1	ENSPREP00000018082	ENSPREP00000026481	RecQ helicase-like 4.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.569
recql4	terf2	ENSPREP00000018082	ENSPREP00000018221	RecQ helicase-like 4.	HTH myb-type domain-containing protein.	0.514
rtel1	blm	ENSPREP00000012657	ENSPREP00000011311	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	BLM RecQ like helicase.	0.783
rtel1	pot1	ENSPREP00000012657	ENSPREP00000024452	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	Telo_bind domain-containing protein.	0.601
rtel1	recql4	ENSPREP00000012657	ENSPREP00000018082	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	RecQ helicase-like 4.	0.706
rtel1	slx4	ENSPREP00000012657	ENSPREP00000000407	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae).	0.715
rtel1	terf1	ENSPREP00000012657	ENSPREP00000026481	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.604