(21 nodes) Bone cell development network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPREP00000003717	Uncharacterized protein. (76 aa)
	LOC103469251	FAM20C golgi associated secretory pathway kinase a. (569 aa)
	SRF	Serum response factor. (243 aa)
	LOC103467580	Glycoprotein IX (platelet). (241 aa)
	srf	Serum response factor b. (570 aa)
	SRC	Tyrosine-protein kinase. (569 aa)
	ptpn6	Protein tyrosine phosphatase non-receptor type 6. (573 aa)
	LOC103467098	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	gp1bb	Glycoprotein Ib platelet subunit beta. (206 aa)
	sh2b3	SH2B adaptor protein 3. (710 aa)
	LOC103481136	FAM20C golgi associated secretory pathway kinase. (526 aa)
	ptpn11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
	LOC103468460	E1A binding protein p300 b. (2737 aa)
	tnfsf11	TNF superfamily member 11; Belongs to the tumor necrosis factor family. (268 aa)
	ABI1	Abl-interactor 1a. (577 aa)
	atp6ap1	ATPase H+ transporting accessory protein 1a. (489 aa)
	lrrk1	Uncharacterized protein. (2016 aa)
	LOC103467856	Tyrosine-protein kinase. (542 aa)
	LOC103482005	E1A binding protein p300 a. (2743 aa)
	LOC103467860	ATPase H+ transporting accessory protein 1b. (446 aa)
	ENSPREP00000003699	SH3 domain-containing protein. (137 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103467098	LOC103467856	ENSPREP00000016883	ENSPREP00000031006	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein kinase.	0.531
LOC103467098	SRC	ENSPREP00000016883	ENSPREP00000016288	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein kinase.	0.531
LOC103467098	ptpn11	ENSPREP00000016883	ENSPREP00000024560	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.901
LOC103467580	gp1bb	ENSPREP00000012254	ENSPREP00000017108	Glycoprotein IX (platelet).	Glycoprotein Ib platelet subunit beta.	0.976
LOC103467856	LOC103467098	ENSPREP00000031006	ENSPREP00000016883	Tyrosine-protein kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.531
LOC103467856	SRC	ENSPREP00000031006	ENSPREP00000016288	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.901
LOC103467856	ptpn11	ENSPREP00000031006	ENSPREP00000024560	Tyrosine-protein kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.531
LOC103467856	ptpn6	ENSPREP00000031006	ENSPREP00000016776	Tyrosine-protein kinase.	Protein tyrosine phosphatase non-receptor type 6.	0.466
LOC103467860	atp6ap1	ENSPREP00000030801	ENSPREP00000002735	ATPase H+ transporting accessory protein 1b.	ATPase H+ transporting accessory protein 1a.	0.903
LOC103468460	LOC103482005	ENSPREP00000026558	ENSPREP00000030842	E1A binding protein p300 b.	E1A binding protein p300 a.	0.902
LOC103482005	LOC103468460	ENSPREP00000030842	ENSPREP00000026558	E1A binding protein p300 a.	E1A binding protein p300 b.	0.902
SRC	LOC103467098	ENSPREP00000016288	ENSPREP00000016883	Tyrosine-protein kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.531
SRC	LOC103467856	ENSPREP00000016288	ENSPREP00000031006	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.901
SRC	ptpn11	ENSPREP00000016288	ENSPREP00000024560	Tyrosine-protein kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.531
SRC	ptpn6	ENSPREP00000016288	ENSPREP00000016776	Tyrosine-protein kinase.	Protein tyrosine phosphatase non-receptor type 6.	0.466
atp6ap1	LOC103467860	ENSPREP00000002735	ENSPREP00000030801	ATPase H+ transporting accessory protein 1a.	ATPase H+ transporting accessory protein 1b.	0.903
gp1bb	LOC103467580	ENSPREP00000017108	ENSPREP00000012254	Glycoprotein Ib platelet subunit beta.	Glycoprotein IX (platelet).	0.976
ptpn11	LOC103467098	ENSPREP00000024560	ENSPREP00000016883	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.901
ptpn11	LOC103467856	ENSPREP00000024560	ENSPREP00000031006	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein kinase.	0.531
ptpn11	SRC	ENSPREP00000024560	ENSPREP00000016288	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein kinase.	0.531