64 items (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tsc1	TSC complex subunit 1b. (1243 aa)
	LOC103478903	Leucine rich repeat containing 24. (630 aa)
	lrrtm4	Uncharacterized protein. (525 aa)
	LOC103473983	Si:dkey-28o19.1. (629 aa)
	nphp1	Nephronophthisis 1. (698 aa)
	Cav1	Uncharacterized protein. (84 aa)
	LOC103471064	Interleukin 1 receptor accessory protein-like 2. (678 aa)
	LOC103475300	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (223 aa)
	eef2k	Eukaryotic elongation factor 2 kinase. (767 aa)
	ENSPREP00000005965	Uncharacterized protein. (237 aa)
	adnp	Activity-dependent neuroprotector homeobox b. (1057 aa)
	lrtm2	Leucine-rich repeats and transmembrane domains 2a. (362 aa)
	itgb1bp1	Integrin beta 1 binding protein 1. (193 aa)
	nrp1	Neuropilin; Belongs to the neuropilin family. (903 aa)
	LOC103479062	Eph receptor B3a. (959 aa)
	irx3	Iroquois homeobox 3a. (457 aa)
	ENSPREP00000009542	Leucine rich repeat transmembrane neuronal 2. (546 aa)
	flrt3	Fibronectin leucine rich transmembrane 3. (650 aa)
	LOC103479092	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (210 aa)
	ephb3	Receptor protein-tyrosine kinase. (1013 aa)
	LOC103460066	Uncharacterized protein. (496 aa)
	il1rapl1	Interleukin 1 receptor accessory protein-like 1a. (715 aa)
	SLITRK1	SLIT and NTRK like family member 1. (703 aa)
	Slitrk5	SLIT and NTRK-like family, member 5a. (890 aa)
	LOC103475908	Uncharacterized protein. (715 aa)
	LOC103467387	Leucine rich repeat transmembrane neuronal 1. (524 aa)
	poldip2	Polymerase (DNA-directed), delta interacting protein 2. (377 aa)
	LOC103465217	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
	LOC103480380	Si:dkeyp-74b6.2. (207 aa)
	lrrn3	Leucine rich repeat neuronal 3b. (709 aa)
	nphp4	Uncharacterized protein. (1207 aa)
	ENSPREP00000015938	Nephronophthisis 4. (230 aa)
	clstn2	Uncharacterized protein. (945 aa)
	agrn	Agrin. (1768 aa)
	agt	Angiotensinogen; Belongs to the serpin family. (452 aa)
	srpx2	Sushi-repeat containing protein X-linked 2. (444 aa)
	Cldn5	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (142 aa)
	flrt2	Fibronectin leucine rich transmembrane protein 2. (651 aa)
	vegfa	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
	LOC103465275	Ig-like domain-containing protein. (790 aa)
	ENSPREP00000020142	Uncharacterized protein. (225 aa)
	LOC103473180	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
	amigo1	Adhesion molecule with Ig-like domain 1. (509 aa)
	LOC103479345	Calsyntenin 2. (867 aa)
	Amigo2	Ig-like domain-containing protein. (517 aa)
	slitrk6	SLIT and NTRK-like family, member 6. (820 aa)
	LOC103465352	Uncharacterized protein. (714 aa)
	clstn1	Calsyntenin 1. (958 aa)
	LOC103476825	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (2011 aa)
	cux2	Homeobox protein cut-like. (1544 aa)
	SEMA4D	Semaphorin 4D; Belongs to the semaphorin family. (900 aa)
	slitrk3	SLIT and NTRK-like family, member 3a. (906 aa)
	LOC103467508	Ig-like domain-containing protein. (451 aa)
	LOC103457801	Fibronectin leucine rich transmembrane protein 2. (659 aa)
	cbln1	Cerebellin 1 precursor. (197 aa)
	slitrk2	SLIT and NTRK-like family, member 2. (892 aa)
	slitrk4	SLIT and NTRK-like family, member 4. (826 aa)
	cldn19	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
	LOC103472693	Protein S100; Belongs to the S-100 family. (100 aa)
	LOC103464216	Ig-like domain-containing protein. (612 aa)
	Vstm5	Uncharacterized protein. (195 aa)
	Amigo3	Adhesion molecule with Ig-like domain 3. (495 aa)
	lrrn1	Leucine rich repeat neuronal 1. (715 aa)
	LOC103464268	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (211 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cav1	Cldn5	ENSPREP00000003891	ENSPREP00000017247	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.468
Cav1	LOC103473180	ENSPREP00000003891	ENSPREP00000020548	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.468
Cldn5	Cav1	ENSPREP00000017247	ENSPREP00000003891	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Uncharacterized protein.	0.468
Cldn5	LOC103473180	ENSPREP00000017247	ENSPREP00000020548	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.658
Cldn5	LOC103475300	ENSPREP00000017247	ENSPREP00000004640	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.687
Cldn5	LOC103479092	ENSPREP00000017247	ENSPREP00000010324	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.749
Cldn5	cldn19	ENSPREP00000017247	ENSPREP00000028831	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.687
ENSPREP00000015938	nphp1	ENSPREP00000015938	ENSPREP00000002672	Nephronophthisis 4.	Nephronophthisis 1.	0.931
ENSPREP00000015938	nphp4	ENSPREP00000015938	ENSPREP00000015922	Nephronophthisis 4.	Uncharacterized protein.	0.899
LOC103464268	agrn	ENSPREP00000031900	ENSPREP00000016797	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	Agrin.	0.410
LOC103473180	Cav1	ENSPREP00000020548	ENSPREP00000003891	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Uncharacterized protein.	0.468
LOC103473180	Cldn5	ENSPREP00000020548	ENSPREP00000017247	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.658
LOC103473180	LOC103475300	ENSPREP00000020548	ENSPREP00000004640	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.687
LOC103473180	LOC103479092	ENSPREP00000020548	ENSPREP00000010324	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.743
LOC103473180	cldn19	ENSPREP00000020548	ENSPREP00000028831	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.687
LOC103475300	Cldn5	ENSPREP00000004640	ENSPREP00000017247	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.687
LOC103475300	LOC103473180	ENSPREP00000004640	ENSPREP00000020548	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.687
LOC103475300	LOC103479092	ENSPREP00000004640	ENSPREP00000010324	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.680
LOC103475300	cldn19	ENSPREP00000004640	ENSPREP00000028831	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.650
LOC103479092	Cldn5	ENSPREP00000010324	ENSPREP00000017247	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.749