STRINGSTRING
Rgcc Rgcc rfwd3 rfwd3 orc1 orc1 e2f1 e2f1 Cdc14a Cdc14a atad5 atad5 LOC103466812 LOC103466812 appl1 appl1 Stil Stil cdk5rap2 cdk5rap2 klhl22 klhl22 pkd1 pkd1 TFAP4 TFAP4 mad1l1 mad1l1 plrg1 plrg1 PLK1 PLK1 gpnmb gpnmb ccnd1 ccnd1 riok2 riok2 plk3 plk3 fbxo5 fbxo5 AIF1 AIF1 gnl3 gnl3 LOC103478965 LOC103478965 ENSPREP00000004304 ENSPREP00000004304 rptor rptor tm4sf5 tm4sf5 mblac1 mblac1 anapc11 anapc11 vps4a vps4a ENSPREP00000005245 ENSPREP00000005245 bcl2 bcl2 VPS4B VPS4B LOC103465183 LOC103465183 ccnh ccnh ddb1 ddb1 CPSF3 CPSF3 taok3 taok3 babam2 babam2 ENSPREP00000006911 ENSPREP00000006911 LOC103479019 LOC103479019 topbp1 topbp1 ENSPREP00000007980 ENSPREP00000007980 ENSPREP00000008127 ENSPREP00000008127 ticrr ticrr cdc16 cdc16 ENSPREP00000008303 ENSPREP00000008303 cdc73 cdc73 cdkn2b cdkn2b LOC103475384 LOC103475384 ENSPREP00000009572 ENSPREP00000009572 fbxo7 fbxo7 mad2l1bp mad2l1bp CDC25B CDC25B cdk1 cdk1 brd7 brd7 bub3 bub3 kank2 kank2 dtl dtl blm blm ENSPREP00000011364 ENSPREP00000011364 cdt1 cdt1 LOC103469188 LOC103469188 cdc7 cdc7 LOC103468682 LOC103468682 haspin haspin nop53 nop53 tpr tpr ZNF830 ZNF830 pla2g4a pla2g4a ENSPREP00000013852 ENSPREP00000013852 prkdc prkdc LOC103459498 LOC103459498 lsm10 lsm10 mtbp mtbp ecd ecd LOC103475599 LOC103475599 ccnb3 ccnb3 cdca5 cdca5 casp2 casp2 CLSPN CLSPN hus1 hus1 ENSPREP00000015300 ENSPREP00000015300 ENSPREP00000015401 ENSPREP00000015401 prmt2 prmt2 LOC103474167 LOC103474167 aven aven zwilch zwilch LOC103480535 LOC103480535 rad17 rad17 fhl1 fhl1 LOC103479248 LOC103479248 mfsd11 mfsd11 LOC103469511 LOC103469511 Clg10h5orf45 Clg10h5orf45 psme1 psme1 LOC103465909 LOC103465909 pidd1 pidd1 LOC103476762 LOC103476762 cul4b cul4b xrcc3 xrcc3 LOC103465931 LOC103465931 cdc27 cdc27 abraxas1 abraxas1 mecp2 mecp2 babam1 babam1 nsmce2 nsmce2 ENSPREP00000018722 ENSPREP00000018722 wac wac ENSPREP00000019024 ENSPREP00000019024 ENSPREP00000019040 ENSPREP00000019040 cdk5rap3 cdk5rap3 rad51c rad51c xpc xpc crlf3 crlf3 ino80 ino80 ENSPREP00000020316 ENSPREP00000020316 cdkn2d cdkn2d LOC103471497 LOC103471497 e2f7 e2f7 Bub1 Bub1 ENSPREP00000021048 ENSPREP00000021048 ENSPREP00000021545 ENSPREP00000021545 LOC103479306 LOC103479306 Adam17 Adam17 ENSPREP00000021987 ENSPREP00000021987 LOC103457156 LOC103457156 ttk ttk ube2c ube2c LOC103479415 LOC103479415 mnat1 mnat1 lcmt1 lcmt1 ENSPREP00000023356 ENSPREP00000023356 znf207 znf207 ints3 ints3 LOC103470128 LOC103470128 ENSPREP00000023746 ENSPREP00000023746 anapc7 anapc7 nbn nbn atm atm bcl7a bcl7a LOC103479391 LOC103479391 cdc26 cdc26 LOC103458871 LOC103458871 zw10 zw10 CTDSP1 CTDSP1 chek1 chek1 dcun1d3 dcun1d3 uimc1 uimc1 rint1 rint1 FZR1 FZR1 plk2 plk2 fbxo31 fbxo31 stox1 stox1 DONSON DONSON foxn3 foxn3 appl2 appl2 cdkn2c cdkn2c anapc4 anapc4 LOC103474461 LOC103474461 ENSPREP00000027944 ENSPREP00000027944 pinx1 pinx1 chfr chfr ercc2 ercc2 LOC103464190 LOC103464190 anapc15 anapc15 ndc80 ndc80 Brcc3 Brcc3 lsm11 lsm11 ctdsp2 ctdsp2 LOC103461892 LOC103461892 LOC103461890 LOC103461890 LOC103466787 LOC103466787 anapc5 anapc5 sass6 sass6 ambra1 ambra1 LOC103463808 LOC103463808 ctdspl ctdspl kntc1 kntc1 cul4a cul4a mad2l1 mad2l1 zfyve19 zfyve19 bub1b bub1b LOC103478861 LOC103478861 cdc6 cdc6 Kmt2e Kmt2e ENSPREP00000032744 ENSPREP00000032744 Spdl1 Spdl1 brca1 brca1 psme2 psme2 LOC103475789 LOC103475789 LOC103475788 LOC103475788 mre11 mre11 LOC103459164 LOC103459164 taok2 taok2 usp47 usp47 cdc23 cdc23
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RgccRegulator of cell cycle. (134 aa)
rfwd3Ring finger and WD repeat domain 3. (893 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (629 aa)
e2f1E2F transcription factor 1. (477 aa)
Cdc14aUncharacterized protein. (135 aa)
atad5ATPase family AAA domain containing 5a. (1822 aa)
LOC103466812Cyclin D2, a; Belongs to the cyclin family. (355 aa)
appl1Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1. (708 aa)
StilUncharacterized protein. (361 aa)
cdk5rap2Uncharacterized protein. (2228 aa)
klhl22Kelch-like family member 22. (673 aa)
pkd1Polycystic kidney disease 1a. (4592 aa)
TFAP4Transcription factor AP-4. (317 aa)
mad1l1Mitotic arrest deficient 1 like 1. (719 aa)
plrg1Pleiotropic regulator 1. (510 aa)
PLK1Serine/threonine-protein kinase PLK. (581 aa)
gpnmbGlycoprotein (transmembrane) nmb. (624 aa)
ccnd1Cyclin D1; Belongs to the cyclin family. (292 aa)
riok2RIO kinase 2 (yeast). (520 aa)
plk3Serine/threonine-protein kinase PLK. (667 aa)
fbxo5F-box protein 5. (376 aa)
AIF1Allograft inflammatory factor 1. (149 aa)
gnl3Guanine nucleotide binding protein-like 3 (nucleolar). (521 aa)
LOC103478965WW domain-containing protein. (511 aa)
ENSPREP00000004304Cnn_1N domain-containing protein. (68 aa)
rptorRegulatory associated protein of MTOR, complex 1. (1350 aa)
tm4sf5Zgc:172079. (203 aa)
mblac1Metallo-beta-lactamase domain containing 1. (216 aa)
anapc11APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
vps4aVacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family. (436 aa)
ENSPREP00000005245Uncharacterized protein. (189 aa)
bcl2BCL2 apoptosis regulator b. (230 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (437 aa)
LOC103465183Cyclin-dependent kinase inhibitor 1A. (156 aa)
ccnhCyclin H; Belongs to the cyclin family. (319 aa)
ddb1Damage-specific DNA binding protein 1. (1102 aa)
CPSF3Cleavage and polyadenylation specific factor 3. (653 aa)
taok3TAO kinase 3a. (950 aa)
babam2BRISC and BRCA1 A complex member 2. (386 aa)
ENSPREP00000006911Uncharacterized protein. (216 aa)
LOC103479019Fizzy/cell division cycle 20 related 1b. (396 aa)
topbp1DNA topoisomerase II binding protein 1. (1453 aa)
ENSPREP00000007980Reverse transcriptase domain-containing protein. (282 aa)
ENSPREP00000008127Reverse transcriptase domain-containing protein. (1242 aa)
ticrrTreslin_N domain-containing protein. (1692 aa)
cdc16Cell division cycle 16 homolog (S. cerevisiae). (618 aa)
ENSPREP00000008303Reverse transcriptase domain-containing protein. (353 aa)
cdc73Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). (576 aa)
cdkn2bCyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (126 aa)
LOC103475384Four and a half LIM domains 1b. (280 aa)
ENSPREP00000009572Reverse transcriptase domain-containing protein. (554 aa)
fbxo7F-box protein 7. (465 aa)
mad2l1bpMAD2L1 binding protein. (372 aa)
CDC25BCell division cycle 25B. (383 aa)
cdk1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (308 aa)
brd7Bromodomain containing 7. (658 aa)
bub3BUB3 mitotic checkpoint protein. (326 aa)
kank2KN motif and ankyrin repeat domains 2. (1003 aa)
dtlDenticleless E3 ubiquitin protein ligase homolog (Drosophila). (704 aa)
blmBLM RecQ like helicase. (1399 aa)
ENSPREP00000011364Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1074 aa)
cdt1Chromatin licensing and DNA replication factor 1. (620 aa)
LOC103469188Transcription factor AP-4 (activating enhancer binding protein 4). (329 aa)
cdc7Cell division cycle 7 homolog (S. cerevisiae). (610 aa)
LOC103468682Uncharacterized protein. (455 aa)
haspinSi:dkeyp-26a9.2. (1200 aa)
nop53Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (431 aa)
tprTranslocated promoter region b, nuclear basket protein. (2383 aa)
ZNF830Zinc finger protein 830. (333 aa)
pla2g4aPhospholipase A2. (749 aa)
ENSPREP00000013852Uncharacterized protein. (148 aa)
prkdcProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (3907 aa)
LOC103459498Cyclin-dependent kinase inhibitor 1D. (179 aa)
lsm10LSM10, U7 small nuclear RNA associated. (131 aa)
mtbpMDM2 binding protein. (745 aa)
ecdEcdysoneless homolog (Drosophila). (669 aa)
LOC103475599TAO kinase 1b. (1015 aa)
ccnb3Cyclin B3; Belongs to the cyclin family. (475 aa)
cdca5Cell division cycle associated 5. (264 aa)
casp2Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (464 aa)
CLSPNClaspin. (1239 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (245 aa)
ENSPREP00000015300Reverse transcriptase domain-containing protein. (415 aa)
ENSPREP00000015401CENP-F_N domain-containing protein. (75 aa)
prmt2Protein arginine methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (379 aa)
LOC103474167TAO kinase 1a. (1013 aa)
avenApoptosis, caspase activation inhibitor. (271 aa)
zwilchZwilch kinetochore protein. (594 aa)
LOC103480535Transmembrane 4 L six family member 5. (214 aa)
rad17RAD17 checkpoint clamp loader component. (705 aa)
fhl1Four and a half LIM domains 1a. (297 aa)
LOC103479248Uncharacterized protein. (537 aa)
mfsd11Major facilitator superfamily domain containing 11. (454 aa)
LOC103469511TAO kinase 2. (1086 aa)
Clg10h5orf45Uncharacterized protein. (78 aa)
psme1Proteasome activator subunit 1. (250 aa)
LOC103465909Cyclin-dependent kinase inhibitor 1Bb. (194 aa)
pidd1P53-induced death domain protein 1. (942 aa)
LOC103476762ALMS_motif domain-containing protein. (417 aa)
cul4bCullin 4B; Belongs to the cullin family. (872 aa)
xrcc3DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (302 aa)
LOC103465931Cyclin-dependent kinase inhibitor 1Cb. (217 aa)
cdc27Cell division cycle 27. (803 aa)
abraxas1Abraxas 1, BRCA1 A complex subunit. (349 aa)
mecp2Methyl CpG binding protein 2. (982 aa)
babam1BRISC and BRCA1 A complex member 1. (355 aa)
nsmce2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (230 aa)
ENSPREP00000018722Reverse transcriptase domain-containing protein. (253 aa)
wacWW domain containing adaptor with coiled-coil a. (543 aa)
ENSPREP00000019024TAO kinase 3b. (437 aa)
ENSPREP00000019040Uncharacterized protein. (93 aa)
cdk5rap3CDK5 regulatory subunit associated protein 3. (506 aa)
rad51cRAD51 paralog C. (377 aa)
xpcXeroderma pigmentosum, complementation group C. (852 aa)
crlf3Cytokine receptor-like factor 3. (419 aa)
ino80INO80 complex ATPase subunit. (1484 aa)
ENSPREP00000020316G protein-coupled receptor 132a; Belongs to the G-protein coupled receptor 1 family. (374 aa)
cdkn2dCyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (164 aa)
LOC103471497Aurora kinase B; Belongs to the protein kinase superfamily. (350 aa)
e2f7E2F transcription factor 7. (798 aa)
Bub1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (210 aa)
ENSPREP00000021048BUB1 N-terminal domain-containing protein. (264 aa)
ENSPREP00000021545Uncharacterized protein. (255 aa)
LOC103479306Translocated promoter region a, nuclear basket protein. (1861 aa)
Adam17Pep_M12B_propep domain-containing protein. (290 aa)
ENSPREP00000021987ADAM metallopeptidase domain 17b. (508 aa)
LOC103457156Cleavage and polyadenylation specific factor 3. (627 aa)
ttkTtk protein kinase. (996 aa)
ube2cUbiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
LOC103479415SMYLE_N domain-containing protein. (1839 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
lcmt1Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (325 aa)
ENSPREP00000023356Retinoblastoma-like 1 (p107). (577 aa)
znf207Zinc finger protein 207, b. (473 aa)
ints3Integrator complex subunit 3. (1019 aa)
LOC103470128Cell division cycle 14B. (525 aa)
ENSPREP00000023746Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (323 aa)
anapc7Anaphase promoting complex subunit 7. (565 aa)
nbnNibrin. (843 aa)
atmNon-specific serine/threonine protein kinase. (3091 aa)
bcl7aBAF chromatin remodeling complex subunit BCL7A. (209 aa)
LOC103479391CULLIN_2 domain-containing protein; Belongs to the cullin family. (766 aa)
cdc26Uncharacterized protein. (62 aa)
LOC103458871ADAM metallopeptidase domain 17a. (800 aa)
zw10Zw10 kinetochore protein. (767 aa)
CTDSP1CTD small phosphatase 1. (310 aa)
chek1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (478 aa)
dcun1d3DCN1-like protein. (326 aa)
uimc1Uncharacterized protein. (985 aa)
rint1RAD50 interactor 1. (787 aa)
FZR1Fizzy/cell division cycle 20 related 1a. (470 aa)
plk2Serine/threonine-protein kinase PLK. (669 aa)
fbxo31F-box protein 31. (585 aa)
stox1Storkhead box 1. (982 aa)
DONSONDownstream neighbor of SON. (586 aa)
foxn3Checkpoint suppressor 1. (483 aa)
appl2Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2. (710 aa)
cdkn2cANK_REP_REGION domain-containing protein. (167 aa)
anapc4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (802 aa)
LOC103474461Cullin 3; Belongs to the cullin family. (767 aa)
ENSPREP00000027944Reverse transcriptase domain-containing protein. (1281 aa)
pinx1PIN2 (TERF1) interacting telomerase inhibitor 1. (378 aa)
chfrCheckpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase. (624 aa)
ercc2Excision repair cross-complementation group 2. (655 aa)
LOC103464190ANK_REP_REGION domain-containing protein. (161 aa)
anapc15Anaphase promoting complex subunit 15. (122 aa)
ndc80NDC80 kinetochore complex component. (642 aa)
Brcc3BRCA1/BRCA2-containing complex, subunit 3. (251 aa)
lsm11LSM11, U7 small nuclear RNA associated. (339 aa)
ctdsp2CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2. (340 aa)
LOC103461892Nucleic acid binding protein 1a. (205 aa)
LOC103461890FCP1 homology domain-containing protein. (972 aa)
LOC103466787Retinoblastoma-like 2 (p130). (1032 aa)
anapc5Anaphase promoting complex subunit 5. (773 aa)
sass6SAS-6 centriolar assembly protein. (584 aa)
ambra1Autophagy/beclin-1 regulator 1b. (1210 aa)
LOC103463808Uncharacterized protein; Belongs to the AAA ATPase family. (411 aa)
ctdsplCTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like a. (292 aa)
kntc1Kinetochore associated 1. (2067 aa)
cul4aCullin 4A; Belongs to the cullin family. (591 aa)
mad2l1MAD2 mitotic arrest deficient-like 1 (yeast). (202 aa)
zfyve19Zinc finger, FYVE domain containing 19. (425 aa)
bub1bBUB1 mitotic checkpoint serine/threonine kinase Bb. (427 aa)
LOC103478861CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b. (283 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (586 aa)
Kmt2eLysine (K)-specific methyltransferase 2E. (602 aa)
ENSPREP00000032744Retinoblastoma 1. (864 aa)
Spdl1Uncharacterized protein. (62 aa)
brca1Uncharacterized protein. (1344 aa)
psme2Proteasome activator subunit 2. (256 aa)
LOC103475789Si:ch211-137i24.10. (192 aa)
LOC103475788Uncharacterized protein. (199 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (611 aa)
LOC103459164Cyclin D2, b; Belongs to the cyclin family. (294 aa)
taok2TAO kinase 2b. (1168 aa)
usp47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1357 aa)
cdc23CDC23 (cell division cycle 23, yeast, homolog). (575 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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