(41 nodes) Positive regulation of mitotic cell cycle phase transition network (Poecilia reticulata)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	plrg1	Pleiotropic regulator 1. (510 aa)
	Stil	Uncharacterized protein. (361 aa)
	LOC103466812	Cyclin D2, a; Belongs to the cyclin family. (355 aa)
	ccnd1	Cyclin D1; Belongs to the cyclin family. (292 aa)
	fbxo5	F-box protein 5. (376 aa)
	AIF1	Allograft inflammatory factor 1. (149 aa)
	rptor	Regulatory associated protein of MTOR, complex 1. (1350 aa)
	mblac1	Metallo-beta-lactamase domain containing 1. (216 aa)
	anapc11	APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
	CPSF3	Cleavage and polyadenylation specific factor 3. (653 aa)
	cdc16	Cell division cycle 16 homolog (S. cerevisiae). (618 aa)
	mad2l1bp	MAD2L1 binding protein. (372 aa)
	CDC25B	Cell division cycle 25B. (383 aa)
	cdt1	Chromatin licensing and DNA replication factor 1. (620 aa)
	cdc7	Cell division cycle 7 homolog (S. cerevisiae). (610 aa)
	lsm10	LSM10, U7 small nuclear RNA associated. (131 aa)
	mtbp	MDM2 binding protein. (745 aa)
	cdca5	Cell division cycle associated 5. (264 aa)
	cul4b	Cullin 4B; Belongs to the cullin family. (872 aa)
	cdc27	Cell division cycle 27. (803 aa)
	mecp2	Methyl CpG binding protein 2. (982 aa)
	nsmce2	NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (230 aa)
	rad51c	RAD51 paralog C. (377 aa)
	Adam17	Pep_M12B_propep domain-containing protein. (290 aa)
	ENSPREP00000021987	ADAM metallopeptidase domain 17b. (508 aa)
	LOC103457156	Cleavage and polyadenylation specific factor 3. (627 aa)
	ube2c	Ubiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
	anapc7	Anaphase promoting complex subunit 7. (565 aa)
	LOC103479391	CULLIN_2 domain-containing protein; Belongs to the cullin family. (766 aa)
	LOC103458871	ADAM metallopeptidase domain 17a. (800 aa)
	stox1	Storkhead box 1. (982 aa)
	LOC103474461	Cullin 3; Belongs to the cullin family. (767 aa)
	lsm11	LSM11, U7 small nuclear RNA associated. (339 aa)
	Rgcc	Regulator of cell cycle. (134 aa)
	anapc5	Anaphase promoting complex subunit 5. (773 aa)
	sass6	SAS-6 centriolar assembly protein. (584 aa)
	cul4a	Cullin 4A; Belongs to the cullin family. (591 aa)
	Kmt2e	Lysine (K)-specific methyltransferase 2E. (602 aa)
	ENSPREP00000032744	Retinoblastoma 1. (864 aa)
	LOC103459164	Cyclin D2, b; Belongs to the cyclin family. (294 aa)
	cdc23	CDC23 (cell division cycle 23, yeast, homolog). (575 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Adam17	ENSPREP00000021987	ENSPREP00000021960	ENSPREP00000021987	Pep_M12B_propep domain-containing protein.	ADAM metallopeptidase domain 17b.	0.932
Adam17	LOC103458871	ENSPREP00000021960	ENSPREP00000025199	Pep_M12B_propep domain-containing protein.	ADAM metallopeptidase domain 17a.	0.902
CDC25B	cdc27	ENSPREP00000010131	ENSPREP00000018474	Cell division cycle 25B.	Cell division cycle 27.	0.443
CPSF3	lsm10	ENSPREP00000006485	ENSPREP00000014642	Cleavage and polyadenylation specific factor 3.	LSM10, U7 small nuclear RNA associated.	0.824
CPSF3	lsm11	ENSPREP00000006485	ENSPREP00000029102	Cleavage and polyadenylation specific factor 3.	LSM11, U7 small nuclear RNA associated.	0.500
ENSPREP00000021987	Adam17	ENSPREP00000021987	ENSPREP00000021960	ADAM metallopeptidase domain 17b.	Pep_M12B_propep domain-containing protein.	0.932
ENSPREP00000032744	LOC103459164	ENSPREP00000032744	ENSPREP00000033744	Retinoblastoma 1.	Cyclin D2, b; Belongs to the cyclin family.	0.980
ENSPREP00000032744	LOC103466812	ENSPREP00000032744	ENSPREP00000001771	Retinoblastoma 1.	Cyclin D2, a; Belongs to the cyclin family.	0.980
ENSPREP00000032744	LOC103474461	ENSPREP00000032744	ENSPREP00000027846	Retinoblastoma 1.	Cullin 3; Belongs to the cullin family.	0.538
ENSPREP00000032744	LOC103479391	ENSPREP00000032744	ENSPREP00000024968	Retinoblastoma 1.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.538
ENSPREP00000032744	anapc11	ENSPREP00000032744	ENSPREP00000004954	Retinoblastoma 1.	APC11 anaphase promoting complex subunit 11 homolog (yeast).	0.637
ENSPREP00000032744	ccnd1	ENSPREP00000032744	ENSPREP00000002680	Retinoblastoma 1.	Cyclin D1; Belongs to the cyclin family.	0.980
ENSPREP00000032744	cdc16	ENSPREP00000032744	ENSPREP00000008226	Retinoblastoma 1.	Cell division cycle 16 homolog (S. cerevisiae).	0.702
ENSPREP00000032744	cdc27	ENSPREP00000032744	ENSPREP00000018474	Retinoblastoma 1.	Cell division cycle 27.	0.687
ENSPREP00000032744	cdt1	ENSPREP00000032744	ENSPREP00000011428	Retinoblastoma 1.	Chromatin licensing and DNA replication factor 1.	0.595
ENSPREP00000032744	ube2c	ENSPREP00000032744	ENSPREP00000022778	Retinoblastoma 1.	Ubiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family.	0.618
LOC103457156	lsm10	ENSPREP00000022035	ENSPREP00000014642	Cleavage and polyadenylation specific factor 3.	LSM10, U7 small nuclear RNA associated.	0.824
LOC103457156	lsm11	ENSPREP00000022035	ENSPREP00000029102	Cleavage and polyadenylation specific factor 3.	LSM11, U7 small nuclear RNA associated.	0.500
LOC103458871	Adam17	ENSPREP00000025199	ENSPREP00000021960	ADAM metallopeptidase domain 17a.	Pep_M12B_propep domain-containing protein.	0.902
LOC103459164	ENSPREP00000032744	ENSPREP00000033744	ENSPREP00000032744	Cyclin D2, b; Belongs to the cyclin family.	Retinoblastoma 1.	0.980