(14 nodes) Regulation of hematopoietic stem cell differentiation network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	hspa9	Heat shock protein 9; Belongs to the heat shock protein 70 family. (679 aa)
	ENSPREP00000007854	Uncharacterized protein. (143 aa)
	nfe2l2	Nuclear factor, erythroid 2-like 2a. (617 aa)
	fgfr4	Fibroblast growth factor receptor 4. (942 aa)
	LOC103458160	Fibroblast growth factor receptor. (814 aa)
	supt5h	Transcription elongation factor SPT5. (1059 aa)
	LOC103477270	Uncharacterized protein. (689 aa)
	ENSPREP00000011628	Uncharacterized protein. (564 aa)
	LOC103477355	Protein kinase domain-containing protein. (582 aa)
	ENSPREP00000013954	Uncharacterized protein. (326 aa)
	LOC103477293	Fibroblast growth factor receptor. (676 aa)
	LOC103480536	Methyltransferase like 3; Belongs to the MT-A70-like family. (287 aa)
	pus7	Pseudouridine synthase 7. (641 aa)
	ythdf2	YTH N(6)-methyladenosine RNA binding protein 2. (639 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000007854	LOC103480536	ENSPREP00000007854	ENSPREP00000015801	Uncharacterized protein.	Methyltransferase like 3; Belongs to the MT-A70-like family.	0.899
LOC103477270	nfe2l2	ENSPREP00000011565	ENSPREP00000007937	Uncharacterized protein.	Nuclear factor, erythroid 2-like 2a.	0.914
LOC103480536	ENSPREP00000007854	ENSPREP00000015801	ENSPREP00000007854	Methyltransferase like 3; Belongs to the MT-A70-like family.	Uncharacterized protein.	0.899
LOC103480536	ythdf2	ENSPREP00000015801	ENSPREP00000028675	Methyltransferase like 3; Belongs to the MT-A70-like family.	YTH N(6)-methyladenosine RNA binding protein 2.	0.506
nfe2l2	LOC103477270	ENSPREP00000007937	ENSPREP00000011565	Nuclear factor, erythroid 2-like 2a.	Uncharacterized protein.	0.914
ythdf2	LOC103480536	ENSPREP00000028675	ENSPREP00000015801	YTH N(6)-methyladenosine RNA binding protein 2.	Methyltransferase like 3; Belongs to the MT-A70-like family.	0.506