(41 nodes) Regulation of epithelial cell apoptotic process network (Poecilia reticulata)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	pdcd4	Programmed cell death 4b. (494 aa)
	LOC103473985	Phospholipase A(2). (149 aa)
	ENSPREP00000002926	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (196 aa)
	LOC103480143	CD248 molecule, endosialin a. (673 aa)
	LOC103480133	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (390 aa)
	LOC103473479	EGF-like domain-containing protein. (217 aa)
	LOC103477745	Tumor necrosis factor b (TNF superfamily, member 2). (249 aa)
	il10	Interleukin 10. (229 aa)
	LOC103471087	Uncharacterized protein. (879 aa)
	nfe2l2	Nuclear factor, erythroid 2-like 2a. (617 aa)
	LOC103466391	Programmed cell death 4a. (434 aa)
	LOC103476642	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (725 aa)
	cd248	Uncharacterized protein. (711 aa)
	fgb	Fibrinogen beta chain. (492 aa)
	tnfaip3	Tumor necrosis factor, alpha-induced protein 3. (799 aa)
	angptl4	Angiopoietin-like 4. (462 aa)
	BAX	BCL2 associated X, apoptosis regulator. (191 aa)
	LOC103469388	Receptor (G protein-coupled) activity modifying protein 2. (202 aa)
	ENSPREP00000014536	Uncharacterized protein. (395 aa)
	ENSPREP00000014929	Wolfram syndrome 1a (wolframin). (784 aa)
	scg2	Uncharacterized protein. (622 aa)
	LOC103471589	CD40 ligand; Belongs to the tumor necrosis factor family. (237 aa)
	LOC103463345	Fibrinogen C-terminal domain-containing protein. (433 aa)
	LOC103459415	Anoctamin. (918 aa)
	GATA2	GATA binding protein 2. (462 aa)
	abl1	Tyrosine-protein kinase. (1124 aa)
	LOC103479394	Secretogranin II (chromogranin C), b. (585 aa)
	sav1	Salvador family WW domain containing protein 1. (383 aa)
	LOC103465060	GATA binding protein 2a. (456 aa)
	tmf1	TATA element modulatory factor 1. (1150 aa)
	abl2	Tyrosine-protein kinase. (1187 aa)
	ndnf	Neuron-derived neurotrophic factor. (571 aa)
	wfs1	Wolfram syndrome 1b (wolframin). (969 aa)
	pdx1	Pancreatic and duodenal homeobox 1. (255 aa)
	nkx2-5	NK2 homeobox 5. (316 aa)
	PLA2G1B	Phospholipase A(2). (147 aa)
	Rgcc	Regulator of cell cycle. (134 aa)
	cast	Uncharacterized protein. (643 aa)
	tnfrsf18	CD40 molecule, TNF receptor superfamily member 5. (314 aa)
	gas6	Uncharacterized protein. (650 aa)
	ENSPREP00000031993	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (131 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000002926	LOC103471589	ENSPREP00000002926	ENSPREP00000015614	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	CD40 ligand; Belongs to the tumor necrosis factor family.	0.948
ENSPREP00000002926	il10	ENSPREP00000002926	ENSPREP00000005577	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Interleukin 10.	0.563
ENSPREP00000002926	tnfrsf18	ENSPREP00000002926	ENSPREP00000031319	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	CD40 molecule, TNF receptor superfamily member 5.	0.583
LOC103463345	angptl4	ENSPREP00000016396	ENSPREP00000012938	Fibrinogen C-terminal domain-containing protein.	Angiopoietin-like 4.	0.903
LOC103471589	ENSPREP00000002926	ENSPREP00000015614	ENSPREP00000002926	CD40 ligand; Belongs to the tumor necrosis factor family.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.948
LOC103471589	il10	ENSPREP00000015614	ENSPREP00000005577	CD40 ligand; Belongs to the tumor necrosis factor family.	Interleukin 10.	0.549
LOC103471589	tnfrsf18	ENSPREP00000015614	ENSPREP00000031319	CD40 ligand; Belongs to the tumor necrosis factor family.	CD40 molecule, TNF receptor superfamily member 5.	0.979
LOC103477745	il10	ENSPREP00000005122	ENSPREP00000005577	Tumor necrosis factor b (TNF superfamily, member 2).	Interleukin 10.	0.504
LOC103477745	tnfrsf18	ENSPREP00000005122	ENSPREP00000031319	Tumor necrosis factor b (TNF superfamily, member 2).	CD40 molecule, TNF receptor superfamily member 5.	0.690
LOC103480133	fgb	ENSPREP00000004625	ENSPREP00000011828	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family.	Fibrinogen beta chain.	0.533
abl1	abl2	ENSPREP00000021197	ENSPREP00000026823	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.915
abl2	abl1	ENSPREP00000026823	ENSPREP00000021197	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.915
angptl4	LOC103463345	ENSPREP00000012938	ENSPREP00000016396	Angiopoietin-like 4.	Fibrinogen C-terminal domain-containing protein.	0.903
fgb	LOC103480133	ENSPREP00000011828	ENSPREP00000004625	Fibrinogen beta chain.	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family.	0.533
il10	ENSPREP00000002926	ENSPREP00000005577	ENSPREP00000002926	Interleukin 10.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.563
il10	LOC103471589	ENSPREP00000005577	ENSPREP00000015614	Interleukin 10.	CD40 ligand; Belongs to the tumor necrosis factor family.	0.549
il10	LOC103477745	ENSPREP00000005577	ENSPREP00000005122	Interleukin 10.	Tumor necrosis factor b (TNF superfamily, member 2).	0.504
il10	tnfrsf18	ENSPREP00000005577	ENSPREP00000031319	Interleukin 10.	CD40 molecule, TNF receptor superfamily member 5.	0.549
tnfrsf18	ENSPREP00000002926	ENSPREP00000031319	ENSPREP00000002926	CD40 molecule, TNF receptor superfamily member 5.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.583
tnfrsf18	LOC103471589	ENSPREP00000031319	ENSPREP00000015614	CD40 molecule, TNF receptor superfamily member 5.	CD40 ligand; Belongs to the tumor necrosis factor family.	0.979