(6 nodes) Stereocilia ankle link complex network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PDZD7	PDZ domain containing 7. (804 aa)
	LOC103469622	Whirlin b. (978 aa)
	ush2a	Usher syndrome 2A (autosomal recessive, mild). (4818 aa)
	LOC103476869	PDZ domain containing 7a. (961 aa)
	ush1c	Usher syndrome 1C. (553 aa)
	whrn	Whirlin a. (828 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103469622	ush1c	ENSPREP00000024882	ENSPREP00000030327	Whirlin b.	Usher syndrome 1C.	0.471
LOC103469622	ush2a	ENSPREP00000024882	ENSPREP00000017452	Whirlin b.	Usher syndrome 2A (autosomal recessive, mild).	0.555
LOC103476869	ush2a	ENSPREP00000026922	ENSPREP00000017452	PDZ domain containing 7a.	Usher syndrome 2A (autosomal recessive, mild).	0.549
PDZD7	ush2a	ENSPREP00000016302	ENSPREP00000017452	PDZ domain containing 7.	Usher syndrome 2A (autosomal recessive, mild).	0.549
ush1c	LOC103469622	ENSPREP00000030327	ENSPREP00000024882	Usher syndrome 1C.	Whirlin b.	0.471
ush1c	ush2a	ENSPREP00000030327	ENSPREP00000017452	Usher syndrome 1C.	Usher syndrome 2A (autosomal recessive, mild).	0.664
ush1c	whrn	ENSPREP00000030327	ENSPREP00000031133	Usher syndrome 1C.	Whirlin a.	0.471
ush2a	LOC103469622	ENSPREP00000017452	ENSPREP00000024882	Usher syndrome 2A (autosomal recessive, mild).	Whirlin b.	0.555
ush2a	LOC103476869	ENSPREP00000017452	ENSPREP00000026922	Usher syndrome 2A (autosomal recessive, mild).	PDZ domain containing 7a.	0.549
ush2a	PDZD7	ENSPREP00000017452	ENSPREP00000016302	Usher syndrome 2A (autosomal recessive, mild).	PDZ domain containing 7.	0.549
ush2a	ush1c	ENSPREP00000017452	ENSPREP00000030327	Usher syndrome 2A (autosomal recessive, mild).	Usher syndrome 1C.	0.664
ush2a	whrn	ENSPREP00000017452	ENSPREP00000031133	Usher syndrome 2A (autosomal recessive, mild).	Whirlin a.	0.555
whrn	ush1c	ENSPREP00000031133	ENSPREP00000030327	Whirlin a.	Usher syndrome 1C.	0.471
whrn	ush2a	ENSPREP00000031133	ENSPREP00000017452	Whirlin a.	Usher syndrome 2A (autosomal recessive, mild).	0.555