(71 nodes) Extrinsic component of plasma membrane network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	snx9	Sorting nexin 9b. (630 aa)
	gcom1	Myocardial zonula adherens protein. (547 aa)
	LOC103475780	WD_REPEATS_REGION domain-containing protein. (223 aa)
	CDH6	Cadherin 6; Cadherins are calcium-dependent cell adhesion proteins. (799 aa)
	CDH10	Cadherin 10; Cadherins are calcium-dependent cell adhesion proteins. (821 aa)
	LOC103470262	Huntingtin interacting protein 1 related b. (1028 aa)
	LOC103467401	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
	ENSPREP00000029577	Erythrocyte membrane protein band 4.1a. (554 aa)
	LOC103473933	EGF-like domain-containing protein. (189 aa)
	LOC103467457	Protein kinase domain-containing protein. (548 aa)
	stac3	SH3 and cysteine rich domain 3. (333 aa)
	hip1	Huntingtin interacting protein 1. (1050 aa)
	LOC103477381	Phosphoinositide phospholipase C. (756 aa)
	kras	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
	LOC103476546	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (924 aa)
	LOC103476549	Uncharacterized protein. (738 aa)
	syap1	BSD domain-containing protein. (392 aa)
	LOC103476551	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (901 aa)
	ENSPREP00000025698	Inhibitor_Mig-6 domain-containing protein. (353 aa)
	ENSPREP00000024995	Protein kinase domain-containing protein. (161 aa)
	ENSPREP00000024937	SH2 domain-containing protein. (152 aa)
	LOC108165961	F-BAR domain-containing protein. (174 aa)
	ENSPREP00000023825	SH2 domain-containing protein. (93 aa)
	LOC103459684	Cyclin dependent kinase 17. (528 aa)
	LOC103473217	SEC14-like lipid binding 7. (404 aa)
	snap91	Synaptosome associated protein 91a. (969 aa)
	GNB4	G protein subunit beta 4. (340 aa)
	gnb5	Guanine nucleotide binding protein (G protein), beta 5a. (380 aa)
	LOC103466018	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (744 aa)
	ENSPREP00000021367	FERM domain-containing protein. (122 aa)
	ctnnb1	Catenin (cadherin-associated protein), beta 1. (783 aa)
	LOC103460235	Cyclin-dependent kinase 16; Belongs to the protein kinase superfamily. (392 aa)
	LOC103468320	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
	gnb3	Guanine nucleotide binding protein (G protein), beta polypeptide 3a. (296 aa)
	LOC103457710	Synaptosome associated protein 91b. (720 aa)
	LOC103463548	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4. (368 aa)
	picalm	Phosphatidylinositol binding clathrin assembly protein b. (588 aa)
	LOC103474215	Synaptotagmin-like 2b. (1682 aa)
	LOC103473710	AP2 associated kinase 1b. (1079 aa)
	LOC103481050	Uncharacterized protein. (530 aa)
	gnb1	Guanine nucleotide binding protein (G protein), beta polypeptide 1a. (340 aa)
	LOC103474919	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family. (762 aa)
	LOC103481657	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
	GNAZ	G protein subunit alpha z. (355 aa)
	LOC103480389	Si:ch211-200p22.4. (642 aa)
	crk	CRK proto-oncogene, adaptor protein. (315 aa)
	wnt2b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (384 aa)
	aak1	AP2 associated kinase 1a. (1055 aa)
	LOC103475391	ENTH domain-containing protein. (593 aa)
	LOC103476642	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (725 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (310 aa)
	stoml2	Stomatin (EPB72)-like 2. (351 aa)
	errfi1	ERBB receptor feedback inhibitor 1a. (430 aa)
	LOC103462170	Guanine nucleotide binding protein (G protein), beta 5b. (345 aa)
	nptx2	Neuronal pentraxin 2a. (449 aa)
	sytl1	Synaptotagmin-like 1. (532 aa)
	LOC103464516	Guanine nucleotide binding protein (G protein), beta polypeptide 1b. (340 aa)
	cdk17	Cyclin dependent kinase 17. (521 aa)
	LOC103460600	DnaJ heat shock protein family (Hsp40) member A3a. (487 aa)
	LOC103462228	Synapse associated protein 1. (363 aa)
	ENSPREP00000003966	FERM domain-containing protein. (181 aa)
	LOC103478711	FERM domain-containing protein. (1627 aa)
	LOC103472243	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	wnt2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
	LOC103469793	SEC14-like lipid binding 8. (410 aa)
	fes	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (824 aa)
	LOC103472833	Guanine nucleotide binding protein (G protein), beta polypeptide 3b. (342 aa)
	LOC103469304	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	plcd4	Phosphoinositide phospholipase C. (750 aa)
	LOC103462833	Guanine nucleotide binding protein (G protein), gamma 13a. (67 aa)
	LOC103476138	Uncharacterized protein. (486 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH10	ctnnb1	ENSPREP00000032782	ENSPREP00000019419	Cadherin 10; Cadherins are calcium-dependent cell adhesion proteins.	Catenin (cadherin-associated protein), beta 1.	0.578
CDH6	ctnnb1	ENSPREP00000032821	ENSPREP00000019419	Cadherin 6; Cadherins are calcium-dependent cell adhesion proteins.	Catenin (cadherin-associated protein), beta 1.	0.578
ENSPREP00000021367	LOC103478711	ENSPREP00000021367	ENSPREP00000003843	FERM domain-containing protein.	FERM domain-containing protein.	0.897
ENSPREP00000023825	crk	ENSPREP00000023825	ENSPREP00000013741	SH2 domain-containing protein.	CRK proto-oncogene, adaptor protein.	0.901
ENSPREP00000023825	crkl	ENSPREP00000023825	ENSPREP00000009681	SH2 domain-containing protein.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.909
ENSPREP00000024937	ENSPREP00000024995	ENSPREP00000024937	ENSPREP00000024995	SH2 domain-containing protein.	Protein kinase domain-containing protein.	0.900
ENSPREP00000024937	LOC108165961	ENSPREP00000024937	ENSPREP00000024919	SH2 domain-containing protein.	F-BAR domain-containing protein.	0.900
ENSPREP00000024995	ENSPREP00000024937	ENSPREP00000024995	ENSPREP00000024937	Protein kinase domain-containing protein.	SH2 domain-containing protein.	0.900
ENSPREP00000024995	LOC108165961	ENSPREP00000024995	ENSPREP00000024919	Protein kinase domain-containing protein.	F-BAR domain-containing protein.	0.900
ENSPREP00000024995	ctnnb1	ENSPREP00000024995	ENSPREP00000019419	Protein kinase domain-containing protein.	Catenin (cadherin-associated protein), beta 1.	0.921
GNAZ	GNB4	ENSPREP00000014948	ENSPREP00000022213	G protein subunit alpha z.	G protein subunit beta 4.	0.668
GNAZ	LOC103462170	ENSPREP00000014948	ENSPREP00000007905	G protein subunit alpha z.	Guanine nucleotide binding protein (G protein), beta 5b.	0.760
GNAZ	LOC103462833	ENSPREP00000014948	ENSPREP00000000520	G protein subunit alpha z.	Guanine nucleotide binding protein (G protein), gamma 13a.	0.403
GNAZ	LOC103464516	ENSPREP00000014948	ENSPREP00000006363	G protein subunit alpha z.	Guanine nucleotide binding protein (G protein), beta polypeptide 1b.	0.668
GNAZ	LOC103468320	ENSPREP00000014948	ENSPREP00000019033	G protein subunit alpha z.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.738
GNAZ	LOC103469304	ENSPREP00000014948	ENSPREP00000001462	G protein subunit alpha z.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.403
GNAZ	LOC103472243	ENSPREP00000014948	ENSPREP00000003752	G protein subunit alpha z.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.772
GNAZ	LOC103472833	ENSPREP00000014948	ENSPREP00000001967	G protein subunit alpha z.	Guanine nucleotide binding protein (G protein), beta polypeptide 3b.	0.529
GNAZ	LOC103475780	ENSPREP00000014948	ENSPREP00000033242	G protein subunit alpha z.	WD_REPEATS_REGION domain-containing protein.	0.668
GNAZ	LOC103481657	ENSPREP00000014948	ENSPREP00000015094	G protein subunit alpha z.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.766