(52 nodes) Cleavage furrow network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	wdr73	WD repeat domain 73. (375 aa)
	LOC103481373	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (325 aa)
	LOC103481333	Supervillin d. (1202 aa)
	LOC103474553	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (334 aa)
	TMEM19	Transmembrane protein 19. (305 aa)
	zfyve19	Zinc finger, FYVE domain containing 19. (425 aa)
	ENSPREP00000031527	Uncharacterized protein. (1802 aa)
	ENSPREP00000031515	LIM zinc-binding domain-containing protein. (211 aa)
	lima1	LIM domain and actin binding 1a. (617 aa)
	LOC103467398	Uncharacterized protein. (210 aa)
	LOC103479487	HP domain-containing protein. (2611 aa)
	LOC103467436	Uncharacterized protein. (192 aa)
	svil	Supervillin a. (2345 aa)
	RAB11FIP3	RAB11 family interacting protein 3. (414 aa)
	pkn1	Protein kinase N1a. (790 aa)
	LOC103465432	Kelch domain containing 8A. (247 aa)
	LOC108165959	Uncharacterized protein. (89 aa)
	ppp1cc	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (342 aa)
	LOC103457902	Uncharacterized protein. (430 aa)
	Ankrd45	ANK_REP_REGION domain-containing protein. (191 aa)
	ENSPREP00000021963	LIM zinc-binding domain-containing protein. (129 aa)
	LOC103468356	Protein kinase N1b. (919 aa)
	LOC103473496	Septin 5b; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (381 aa)
	LOC103467136	Uncharacterized protein. (219 aa)
	septin7	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (465 aa)
	rab11fip4	RAB11 family interacting protein 4 (class II) b. (514 aa)
	LOC103464682	Ras homolog family member Ca. (193 aa)
	LOC103470042	Zgc:63587; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (348 aa)
	septin5	Septin 5a; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (376 aa)
	ENSPREP00000016383	ADP-ribosylation factor 6b. (113 aa)
	LOC103466529	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (894 aa)
	LOC103459010	Pellino E3 ubiquitin protein ligase family member 2. (424 aa)
	LOC103468963	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (334 aa)
	LOC103469336	Supervillin c. (1593 aa)
	LOC103475634	Septin 4a; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (524 aa)
	LOC103466989	Uncharacterized protein. (193 aa)
	LOC103466606	Proline-serine-threonine phosphatase interacting protein 1a. (410 aa)
	KIF23	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (854 aa)
	pkn2	Protein kinase N2. (975 aa)
	LOC103479105	Septin 2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (374 aa)
	LOC103468194	RAB11 family interacting protein 4 (class II) a. (603 aa)
	RHOB	Ras homolog family member B. (156 aa)
	LOC103474060	Protein kinase N3. (1203 aa)
	rab21	RAB21, member RAS oncogene family. (220 aa)
	LOC103465141	Uncharacterized protein. (193 aa)
	pkn3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	klhdc8b	Kelch domain containing 8B. (354 aa)
	ENSPREP00000004017	Septin 15; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (202 aa)
	ENSPREP00000003990	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (105 aa)
	ENSPREP00000002009	Uncharacterized protein. (68 aa)
	LOC103477704	Septin 7b; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (386 aa)
	mastl	Microtubule associated serine/threonine kinase-like. (801 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000002009	LOC103470042	ENSPREP00000002009	ENSPREP00000017199	Uncharacterized protein.	Zgc:63587; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.698
ENSPREP00000002009	LOC103473496	ENSPREP00000002009	ENSPREP00000020521	Uncharacterized protein.	Septin 5b; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.438
ENSPREP00000002009	LOC103474553	ENSPREP00000002009	ENSPREP00000032526	Uncharacterized protein.	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.524
ENSPREP00000002009	LOC103475634	ENSPREP00000002009	ENSPREP00000013158	Uncharacterized protein.	Septin 4a; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.436
ENSPREP00000002009	LOC103479105	ENSPREP00000002009	ENSPREP00000011062	Uncharacterized protein.	Septin 2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.698
ENSPREP00000002009	septin5	ENSPREP00000002009	ENSPREP00000017157	Uncharacterized protein.	Septin 5a; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.435
ENSPREP00000003990	LOC103470042	ENSPREP00000003990	ENSPREP00000017199	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	Zgc:63587; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.699
ENSPREP00000003990	LOC103473496	ENSPREP00000003990	ENSPREP00000020521	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	Septin 5b; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.446
ENSPREP00000003990	LOC103474553	ENSPREP00000003990	ENSPREP00000032526	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.477
ENSPREP00000003990	LOC103475634	ENSPREP00000003990	ENSPREP00000013158	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	Septin 4a; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.442
ENSPREP00000003990	LOC103479105	ENSPREP00000003990	ENSPREP00000011062	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	Septin 2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.699
ENSPREP00000003990	septin5	ENSPREP00000003990	ENSPREP00000017157	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	Septin 5a; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.444
ENSPREP00000004017	LOC103470042	ENSPREP00000004017	ENSPREP00000017199	Septin 15; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	Zgc:63587; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.709
ENSPREP00000004017	LOC103473496	ENSPREP00000004017	ENSPREP00000020521	Septin 15; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	Septin 5b; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.455
ENSPREP00000004017	LOC103474553	ENSPREP00000004017	ENSPREP00000032526	Septin 15; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.421
ENSPREP00000004017	LOC103475634	ENSPREP00000004017	ENSPREP00000013158	Septin 15; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	Septin 4a; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.421
ENSPREP00000004017	LOC103479105	ENSPREP00000004017	ENSPREP00000011062	Septin 15; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	Septin 2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.690
ENSPREP00000004017	septin5	ENSPREP00000004017	ENSPREP00000017157	Septin 15; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	Septin 5a; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.455
ENSPREP00000016383	KIF23	ENSPREP00000016383	ENSPREP00000011393	ADP-ribosylation factor 6b.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.780
ENSPREP00000016383	LOC103466529	ENSPREP00000016383	ENSPREP00000016294	ADP-ribosylation factor 6b.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.780