STRINGSTRING
LOC103460214 LOC103460214 cdc45 cdc45 glyr1 glyr1 vps72 vps72 brf2 brf2 LOC103476203 LOC103476203 LOC103474931 LOC103474931 pold2 pold2 ENSPREP00000013988 ENSPREP00000013988 LOC103476702 LOC103476702 ENSPREP00000013055 ENSPREP00000013055 ENSPREP00000012913 ENSPREP00000012913 LOC103474858 LOC103474858 KDM1B KDM1B LOC103474859 LOC103474859 LOC103479695 LOC103479695 cdt1 cdt1 gtf2b gtf2b gins4 gins4 prim1 prim1 ENSPREP00000009961 ENSPREP00000009961 ENSPREP00000009934 ENSPREP00000009934 ENSPREP00000009489 ENSPREP00000009489 ENSPREP00000007704 ENSPREP00000007704 rpa2 rpa2 ENSPREP00000007462 ENSPREP00000007462 LOC103458137 LOC103458137 LOC103459291 LOC103459291 ENSPREP00000007137 ENSPREP00000007137 LOC103461301 LOC103461301 LOC103475985 LOC103475985 H2AZ1 H2AZ1 hmga2 hmga2 yeats4 yeats4 myog myog hhex hhex gins3 gins3 ENSPREP00000002301 ENSPREP00000002301 LOC103470367 LOC103470367 mphosph8 mphosph8 ENSPREP00000001668 ENSPREP00000001668 clg1h19orf53 clg1h19orf53 ENSPREP00000000287 ENSPREP00000000287 LOC103474640 LOC103474640 pold4 pold4 prim2 prim2 ENSPREP00000033142 ENSPREP00000033142 LOC103465552 LOC103465552 cdc6 cdc6 ercc3 ercc3 orc3 orc3 LOC103472768 LOC103472768 ENSPREP00000030043 ENSPREP00000030043 ENSPREP00000029980 ENSPREP00000029980 nkx2-5 nkx2-5 ten1 ten1 pold3 pold3 H3-3B H3-3B rag2 rag2 rag1 rag1 ENSPREP00000027875 ENSPREP00000027875 DONSON DONSON LOC103481073 LOC103481073 terf1 terf1 rad52 rad52 pola2 pola2 tbx4 tbx4 dars2 dars2 pola1 pola1 LOC103473796 LOC103473796 LOC103459607 LOC103459607 TSHZ1 TSHZ1 pold1 pold1 gins1 gins1 LOC103470692 LOC103470692 rpa3 rpa3 gins2 gins2 ENSPREP00000017888 ENSPREP00000017888
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103460214Uncharacterized protein. (269 aa)
cdc45CDC45 cell division cycle 45 homolog (S. cerevisiae). (573 aa)
glyr1Glyoxylate reductase 1 homolog (Arabidopsis). (424 aa)
vps72Vacuolar protein sorting 72 homolog a. (361 aa)
brf2BRF2 RNA polymerase III transcription initiation factor subunit. (443 aa)
LOC103476203Histone domain-containing protein. (203 aa)
LOC103474931RING-type domain-containing protein. (248 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (471 aa)
ENSPREP00000013988Uncharacterized protein. (163 aa)
LOC103476702Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1a. (423 aa)
ENSPREP00000013055Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (149 aa)
ENSPREP00000012913Histone domain-containing protein. (159 aa)
LOC103474858Histone H3; Belongs to the histone H3 family. (138 aa)
KDM1BLysine demethylase 1B. (579 aa)
LOC103474859Histone domain-containing protein. (111 aa)
LOC103479695Histone H2B; Belongs to the histone H2B family. (116 aa)
cdt1Chromatin licensing and DNA replication factor 1. (620 aa)
gtf2bGeneral transcription factor IIB. (318 aa)
gins4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (224 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (401 aa)
ENSPREP00000009961annotation not available (65 aa)
ENSPREP00000009934Uncharacterized protein; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (65 aa)
ENSPREP00000009489Zgc:163040. (93 aa)
ENSPREP00000007704Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (98 aa)
rpa2Replication protein A2. (256 aa)
ENSPREP00000007462Uncharacterized protein. (102 aa)
LOC103458137TFIIB-type domain-containing protein. (682 aa)
LOC103459291Uncharacterized protein. (1299 aa)
ENSPREP00000007137Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
LOC103461301Histone H3; Belongs to the histone H3 family. (90 aa)
LOC103475985TERF1 (TRF1)-interacting nuclear factor 2. (560 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
hmga2Uncharacterized protein. (115 aa)
yeats4YEATS domain containing 4. (226 aa)
myogMyogenin. (246 aa)
hhexHomeobox domain-containing protein. (296 aa)
gins3GINS complex subunit 3. (211 aa)
ENSPREP00000002301Histone H3; Belongs to the histone H3 family. (92 aa)
LOC103470367Uncharacterized protein. (539 aa)
mphosph8Chromo domain-containing protein. (1294 aa)
ENSPREP00000001668ANK_REP_REGION domain-containing protein. (254 aa)
clg1h19orf53Zgc:136864. (97 aa)
ENSPREP00000000287Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
LOC103474640Histone H2A; Belongs to the histone H2A family. (138 aa)
pold4Uncharacterized protein. (89 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (506 aa)
ENSPREP00000033142Endo/exonuclease/phosphatase domain-containing protein. (411 aa)
LOC103465552GATA binding protein 1a. (426 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (586 aa)
ercc3Excision repair cross-complementation group 3. (783 aa)
orc3Origin recognition complex, subunit 3. (723 aa)
LOC103472768Histone H2A; Belongs to the histone H2A family. (143 aa)
ENSPREP00000030043Histone H2B; Belongs to the histone H2B family. (161 aa)
ENSPREP00000029980Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (95 aa)
nkx2-5NK2 homeobox 5. (316 aa)
ten1TEN1 subunit of CST complex. (134 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (438 aa)
H3-3BHistone H3; Belongs to the histone H3 family. (138 aa)
rag2Recombination activating gene 2. (533 aa)
rag1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (994 aa)
ENSPREP00000027875Histone H3; Belongs to the histone H3 family. (96 aa)
DONSONDownstream neighbor of SON. (586 aa)
LOC103481073Histone H3.3. (136 aa)
terf1Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (367 aa)
rad52RAD52 homolog, DNA repair protein. (343 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (669 aa)
tbx4T-box transcription factor 4. (549 aa)
dars2Aspartyl-tRNA synthetase 2, mitochondrial. (604 aa)
pola1DNA polymerase. (1478 aa)
LOC103473796T-box transcription factor 5a. (524 aa)
LOC103459607Uncharacterized protein. (967 aa)
TSHZ1Teashirt zinc finger homeobox 1. (1230 aa)
pold1DNA polymerase. (1102 aa)
gins1GINS complex subunit 1 (Psf1 homolog). (196 aa)
LOC103470692Histone H2A; Belongs to the histone H2A family. (128 aa)
rpa3Replication protein A3. (122 aa)
gins2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (186 aa)
ENSPREP00000017888BRF1 RNA polymerase III transcription initiation factor subunit b. (612 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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