(33 nodes) Plasma lipoprotein particle network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	lcat	Lecithin-cholesterol acyltransferase. (434 aa)
	vldlr	Very low density lipoprotein receptor. (830 aa)
	LOC108166637	Protein kinase domain-containing protein. (586 aa)
	cetp	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (454 aa)
	apom	Uncharacterized protein. (295 aa)
	LOC103477850	Uncharacterized protein. (255 aa)
	LOC103477849	Uncharacterized protein. (255 aa)
	LOC103477848	Apolipoprotein Eb. (265 aa)
	apoc1	Uncharacterized protein. (83 aa)
	LOC103477845	Uncharacterized protein. (97 aa)
	lrp8	Uncharacterized protein. (937 aa)
	apob	Apolipoprotein Ba. (4338 aa)
	LOC103457447	Apolipoprotein Bb, tandem duplicate 2. (3356 aa)
	ENSPREP00000010257	Uncharacterized protein. (434 aa)
	ENSPREP00000010344	Vitellogenin domain-containing protein. (759 aa)
	LOC103474828	Apolipoprotein A-Ib. (263 aa)
	LOC103475662	Prenylcysteine oxidase 1 like. (283 aa)
	LOC103463504	Uncharacterized protein. (584 aa)
	LOC103473017	Apolipoprotein Ea. (251 aa)
	pcyox1	Prenylcysteine oxidase 1. (506 aa)
	LOC103463535	Scaffold attachment factor B. (767 aa)
	lpl	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (517 aa)
	LOC103463532	PLAT domain-containing protein. (507 aa)
	ldlr	Low density lipoprotein receptor a. (811 aa)
	scarb1	Scavenger receptor class B, member 1; Belongs to the CD36 family. (490 aa)
	LOC103468275	Low density lipoprotein receptor b. (906 aa)
	pltp	Phospholipid transfer protein. (478 aa)
	apof	Apolipoprotein F. (426 aa)
	LOC103480049	Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (122 aa)
	LOC103463058	Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor. (861 aa)
	LOC103474590	Zgc:162608. (331 aa)
	ENSPREP00000033842	Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (113 aa)
	lipc	Lipase, hepatic a. (501 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000010257	ENSPREP00000010344	ENSPREP00000010257	ENSPREP00000010344	Uncharacterized protein.	Vitellogenin domain-containing protein.	0.739
ENSPREP00000010257	LOC103463058	ENSPREP00000010257	ENSPREP00000031068	Uncharacterized protein.	Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor.	0.468
ENSPREP00000010257	LOC103468275	ENSPREP00000010257	ENSPREP00000021897	Uncharacterized protein.	Low density lipoprotein receptor b.	0.468
ENSPREP00000010257	LOC103473017	ENSPREP00000010257	ENSPREP00000013094	Uncharacterized protein.	Apolipoprotein Ea.	0.674
ENSPREP00000010257	LOC103474828	ENSPREP00000010257	ENSPREP00000010904	Uncharacterized protein.	Apolipoprotein A-Ib.	0.801
ENSPREP00000010257	LOC103477848	ENSPREP00000010257	ENSPREP00000006664	Uncharacterized protein.	Apolipoprotein Eb.	0.757
ENSPREP00000010257	LOC103477849	ENSPREP00000010257	ENSPREP00000006633	Uncharacterized protein.	Uncharacterized protein.	0.816
ENSPREP00000010257	LOC103477850	ENSPREP00000010257	ENSPREP00000006628	Uncharacterized protein.	Uncharacterized protein.	0.816
ENSPREP00000010257	apoc1	ENSPREP00000010257	ENSPREP00000006707	Uncharacterized protein.	Uncharacterized protein.	0.478
ENSPREP00000010257	apof	ENSPREP00000010257	ENSPREP00000025047	Uncharacterized protein.	Apolipoprotein F.	0.653
ENSPREP00000010257	cetp	ENSPREP00000010257	ENSPREP00000003448	Uncharacterized protein.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.675
ENSPREP00000010257	ldlr	ENSPREP00000010257	ENSPREP00000021780	Uncharacterized protein.	Low density lipoprotein receptor a.	0.468
ENSPREP00000010257	lrp8	ENSPREP00000010257	ENSPREP00000007172	Uncharacterized protein.	Uncharacterized protein.	0.468
ENSPREP00000010257	pltp	ENSPREP00000010257	ENSPREP00000023197	Uncharacterized protein.	Phospholipid transfer protein.	0.481
ENSPREP00000010257	scarb1	ENSPREP00000010257	ENSPREP00000021860	Uncharacterized protein.	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.727
ENSPREP00000010257	vldlr	ENSPREP00000010257	ENSPREP00000001586	Uncharacterized protein.	Very low density lipoprotein receptor.	0.468
ENSPREP00000010344	ENSPREP00000010257	ENSPREP00000010344	ENSPREP00000010257	Vitellogenin domain-containing protein.	Uncharacterized protein.	0.739
ENSPREP00000010344	LOC103463058	ENSPREP00000010344	ENSPREP00000031068	Vitellogenin domain-containing protein.	Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor.	0.468
ENSPREP00000010344	LOC103468275	ENSPREP00000010344	ENSPREP00000021897	Vitellogenin domain-containing protein.	Low density lipoprotein receptor b.	0.468
ENSPREP00000010344	LOC103473017	ENSPREP00000010344	ENSPREP00000013094	Vitellogenin domain-containing protein.	Apolipoprotein Ea.	0.674