STRINGSTRING
ENDOV ENDOV LOC103481378 LOC103481378 patl2 patl2 LOC103470856 LOC103470856 tdrd1 tdrd1 henmt1 henmt1 ENSPREP00000033092 ENSPREP00000033092 LOC103456706 LOC103456706 ENSPREP00000032886 ENSPREP00000032886 LOC103467822 LOC103467822 lgalsl lgalsl edc4 edc4 xrn1 xrn1 zc3h12b-2 zc3h12b-2 ENSPREP00000030660 ENSPREP00000030660 hnrnpl hnrnpl csdc2 csdc2 pabpc1 pabpc1 ENSPREP00000030212 ENSPREP00000030212 zc3h12d zc3h12d ENSPREP00000029968 ENSPREP00000029968 mov10 mov10 LOC103481169 LOC103481169 ythdf3 ythdf3 piwil2 piwil2 pan3 pan3 ythdf2 ythdf2 LOC103473317 LOC103473317 BTBD1 BTBD1 ENSPREP00000028080 ENSPREP00000028080 LOC103457790 LOC103457790 Top1 Top1 trim71 trim71 ddx4 ddx4 ENSPREP00000026261 ENSPREP00000026261 btbd2 btbd2 YTHDF1 YTHDF1 rc3h1 rc3h1 tia1 tia1 mex3a mex3a tnrc6b tnrc6b LOC103481147 LOC103481147 ybx1 ybx1 RBPMS RBPMS poldip3 poldip3 ddx6 ddx6 edc3 edc3 HABP4 HABP4 LOC103467939 LOC103467939 LOC103469131 LOC103469131 PPP1R27 PPP1R27 mcrip1 mcrip1 LOC103469127 LOC103469127 ENSPREP00000022562 ENSPREP00000022562 ENSPREP00000022545 ENSPREP00000022545 sumo1 sumo1 atxn2 atxn2 LOC103480553 LOC103480553 LOC103461055 LOC103461055 LOC103470725 LOC103470725 uhmk1 uhmk1 carhsp1 carhsp1 tdrd5 tdrd5 dcp2 dcp2 YTHDC2 YTHDC2 LOC103476186 LOC103476186 LOC103464680 LOC103464680 LOC103458435 LOC103458435 LOC103472449 LOC103472449 LOC103475429 LOC103475429 ago4 ago4 fastkd2 fastkd2 mov10l1 mov10l1 dhx30 dhx30 ENSPREP00000014507 ENSPREP00000014507 LOC103474153 LOC103474153 lsm1 lsm1 LIMD1 LIMD1 LOC103473053 LOC103473053 nrde2 nrde2 rc3h2 rc3h2 ENSPREP00000013186 ENSPREP00000013186 eif2s1 eif2s1 g3bp1 g3bp1 zfand1 zfand1 kiaa0355 kiaa0355 HNRNPLL HNRNPLL Pum2 Pum2 pum2 pum2 LOC103477771 LOC103477771 LOC103477773 LOC103477773 LOC103477783 LOC103477783 ENSPREP00000008764 ENSPREP00000008764 ENSPREP00000008696 ENSPREP00000008696 LOC103463278 LOC103463278 larp1 larp1 LOC103465136 LOC103465136 zc3h12a zc3h12a Lin28a Lin28a pum1 pum1 LOC103475990 LOC103475990 tdrkh tdrkh patl1 patl1 LOC103480200 LOC103480200 ppp1r27 ppp1r27 ENSPREP00000004666 ENSPREP00000004666 fmr1 fmr1 dhx36 dhx36 ddx28 ddx28 tial1 tial1 pqbp1 pqbp1 asz1 asz1 trub2 trub2 dis3l2 dis3l2 EIF4ENIF1 EIF4ENIF1 LOC103467732 LOC103467732 LOC103472230 LOC103472230 piwil1 piwil1 g3bp2 g3bp2 LOC103478280 LOC103478280 pabpc4 pabpc4 ogfod1 ogfod1 pan2 pan2 cnot9 cnot9 dcp1a dcp1a nanos3 nanos3 mcrip2 mcrip2 gde1 gde1 tdrd7 tdrd7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENDOVEndonuclease V. (220 aa)
LOC103481378LsmAD domain-containing protein. (1017 aa)
patl2PAT1 homolog 2. (593 aa)
LOC103470856Uncharacterized protein. (540 aa)
tdrd1Tudor domain containing 1. (1184 aa)
henmt1HEN methyltransferase 1. (360 aa)
ENSPREP00000033092Uncharacterized protein. (546 aa)
LOC103456706Uncharacterized protein. (819 aa)
ENSPREP00000032886DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (573 aa)
LOC103467822Zgc:193690. (439 aa)
lgalslGalectin. (167 aa)
edc4Enhancer of mRNA decapping 4. (1333 aa)
xrn15'-3' exoribonuclease 1. (1705 aa)
zc3h12b-2Zinc finger CCCH-type containing 12B. (856 aa)
ENSPREP00000030660Uncharacterized protein. (160 aa)
hnrnplHeterogeneous nuclear ribonucleoprotein L. (494 aa)
csdc2Cold shock domain containing C2, RNA binding a. (157 aa)
pabpc1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (639 aa)
ENSPREP00000030212Nanos homolog 2; Belongs to the nanos family. (116 aa)
zc3h12dC3H1-type domain-containing protein. (570 aa)
ENSPREP00000029968Galectin. (180 aa)
mov10Moloney leukemia virus 10b, tandem duplicate 1. (1011 aa)
LOC103481169DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (597 aa)
ythdf3YTH N(6)-methyladenosine RNA binding protein 3. (604 aa)
piwil2Piwi-like RNA-mediated gene silencing 2; Belongs to the argonaute family. (1055 aa)
pan3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (792 aa)
ythdf2YTH N(6)-methyladenosine RNA binding protein 2. (639 aa)
LOC103473317Cytotoxic granule-associated RNA binding protein 1, like. (386 aa)
BTBD1BTB domain containing 1. (484 aa)
ENSPREP00000028080Piwi domain-containing protein. (177 aa)
LOC103457790Tudor domain containing 6. (2185 aa)
Top1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (606 aa)
trim71Tripartite motif containing 71, E3 ubiquitin protein ligase. (831 aa)
ddx4DEAD (Asp-Glu-Ala-Asp) box polypeptide 4; Belongs to the DEAD box helicase family. (639 aa)
ENSPREP00000026261Uncharacterized protein. (1093 aa)
btbd2BTB (POZ) domain containing 2b. (577 aa)
YTHDF1YTH N6-methyladenosine RNA binding protein 1. (610 aa)
rc3h1Ring finger and CCCH-type domains 1b. (1119 aa)
tia1TIA1 cytotoxic granule-associated RNA binding protein. (419 aa)
mex3aRING-type domain-containing protein. (527 aa)
tnrc6bSi:dkey-46g23.1. (2000 aa)
LOC103481147TNRC6-PABC_bdg domain-containing protein. (1685 aa)
ybx1Y box binding protein 1. (299 aa)
RBPMSRNA binding protein, mRNA processing factor. (267 aa)
poldip3Polymerase (DNA-directed), delta interacting protein 3. (494 aa)
ddx6DEAD (Asp-Glu-Ala-Asp) box helicase 6; Belongs to the DEAD box helicase family. (482 aa)
edc3Enhancer of mRNA decapping 3 homolog (S. cerevisiae). (478 aa)
HABP4Hyaluronan binding protein 4. (361 aa)
LOC103467939Poly(A) binding protein, cytoplasmic 1-like. (412 aa)
LOC103469131Platelet/endothelial cell adhesion molecule 1. (797 aa)
PPP1R27Protein phosphatase 1 regulatory subunit 27. (233 aa)
mcrip1Uncharacterized protein. (63 aa)
LOC103469127Aly/REF export factor. (270 aa)
ENSPREP00000022562Tudor domain containing 9. (993 aa)
ENSPREP00000022545PABC domain-containing protein. (143 aa)
sumo1Small ubiquitin like modifier 1. (205 aa)
atxn2Ataxin 2. (1064 aa)
LOC103480553Tudor domain containing 7 b. (1139 aa)
LOC103461055Fragile X mental retardation 1. (400 aa)
LOC103470725G-rich RNA sequence binding factor 1. (415 aa)
uhmk1U2AF homology motif (UHM) kinase 1. (443 aa)
carhsp1Calcium regulated heat stable protein 1. (158 aa)
tdrd5Uncharacterized protein. (756 aa)
dcp2Decapping mRNA 2. (398 aa)
YTHDC2YTH domain containing 2. (1418 aa)
LOC103476186RRM domain-containing protein. (516 aa)
LOC103464680Mov10 RISC complex RNA helicase a. (992 aa)
LOC103458435ELAV-like protein; Belongs to the RRM elav family. (348 aa)
LOC103472449Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (634 aa)
LOC103475429C3H1-type domain-containing protein. (931 aa)
ago4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (913 aa)
fastkd2FAST kinase domains 2. (612 aa)
mov10l1Uncharacterized protein. (1139 aa)
dhx30DEAH (Asp-Glu-Ala-His) box helicase 30. (1083 aa)
ENSPREP00000014507UBA_6 domain-containing protein. (200 aa)
LOC103474153Dynein light chain. (89 aa)
lsm1U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (133 aa)
LIMD1LIM domains containing 1. (540 aa)
LOC103473053Uncharacterized protein; Belongs to the argonaute family. (695 aa)
nrde2NRDE-2, necessary for RNA interference, domain containing. (1204 aa)
rc3h2Ring finger and CCCH-type domains 2. (1110 aa)
ENSPREP00000013186Uncharacterized protein. (199 aa)
eif2s1Eukaryotic translation initiation factor 2, subunit 1 alpha b. (310 aa)
g3bp1GTPase activating protein (SH3 domain) binding protein 1. (488 aa)
zfand1Zinc finger, AN1-type domain 1. (269 aa)
kiaa0355Si:ch211-79l17.1. (1091 aa)
HNRNPLLHeterogeneous nuclear ribonucleoprotein L like. (513 aa)
Pum2Uncharacterized protein. (121 aa)
pum2Pumilio RNA-binding family member 2. (986 aa)
LOC103477771Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (867 aa)
LOC103477773Argonaute RISC component 1; Belongs to the argonaute family. (858 aa)
LOC103477783Proline-rich nuclear receptor coactivator 2. (155 aa)
ENSPREP00000008764Uncharacterized protein. (240 aa)
ENSPREP00000008696HTH La-type RNA-binding domain-containing protein. (311 aa)
LOC103463278ELAV-like protein; Belongs to the RRM elav family. (360 aa)
larp1La ribonucleoprotein domain family, member 1. (984 aa)
LOC103465136RNA pseudouridine synthase D4. (386 aa)
zc3h12aZinc finger CCCH-type containing 12A. (623 aa)
Lin28aCCHC-type domain-containing protein. (202 aa)
pum1Pumilio RNA-binding family member 1. (1163 aa)
LOC103475990Ajuba LIM protein. (658 aa)
tdrkhTudor and KH domain containing. (587 aa)
patl1PAT1 homolog 1, processing body mRNA decay factor. (734 aa)
LOC103480200RNA binding motif protein 4.2. (376 aa)
ppp1r27Protein phosphatase 1, regulatory subunit 27b. (167 aa)
ENSPREP00000004666Si:dkey-237i9.8. (616 aa)
fmr1Fragile X mental retardation 1. (273 aa)
dhx36DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1057 aa)
ddx28DEAD (Asp-Glu-Ala-Asp) box polypeptide 28. (569 aa)
tial1TIA1 cytotoxic granule-associated RNA binding protein-like 1. (382 aa)
pqbp1Polyglutamine binding protein 1. (153 aa)
asz1Ankyrin repeat, SAM and basic leucine zipper domain containing 1. (472 aa)
trub2TruB pseudouridine (psi) synthase family member 2. (338 aa)
dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1060 aa)
EIF4ENIF1Eukaryotic translation initiation factor 4E nuclear import factor 1. (953 aa)
LOC103467732YTH N(6)-methyladenosine RNA binding protein 1. (609 aa)
LOC103472230Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (894 aa)
piwil1Piwi-like RNA-mediated gene silencing 1; Belongs to the argonaute family. (840 aa)
g3bp2Zgc:56304. (506 aa)
LOC103478280C3H1-type domain-containing protein. (884 aa)
pabpc4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (626 aa)
ogfod12-oxoglutarate and iron-dependent oxygenase domain containing 1. (459 aa)
pan2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1211 aa)
cnot9CCR4-NOT transcription complex subunit 9. (299 aa)
dcp1aDecapping mRNA 1A. (491 aa)
nanos3Nanos homolog 3; Belongs to the nanos family. (209 aa)
mcrip2Si:dkey-44g23.5. (144 aa)
gde1Glycerophosphodiester phosphodiesterase 1. (329 aa)
tdrd7Tudor domain containing 7 a. (1192 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (40%) [HD]