(30 nodes) Melanosome network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103469428	Zgc:91968. (235 aa)
	gpr143	G protein-coupled receptor 143. (450 aa)
	dct	Dopachrome tautomerase. (528 aa)
	rab32	RAB32a, member RAS oncogene family. (223 aa)
	slc45a2	Solute carrier family 45 member 2. (578 aa)
	Slc45a1	Uncharacterized protein. (142 aa)
	sytl1	Synaptotagmin-like 1. (532 aa)
	kcp	Si:dkey-266m15.6. (2045 aa)
	anxa6	Annexin. (665 aa)
	pdia6	Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family. (432 aa)
	tmem33	Transmembrane protein 33. (248 aa)
	LOC103475390	RAB38c, member of RAS oncogene family. (260 aa)
	LOC103480388	Zgc:162171. (251 aa)
	abcb6	ATP-binding cassette, sub-family B (MDR/TAP), member 6a. (863 aa)
	mfsd12	Major facilitator superfamily domain containing 12a. (480 aa)
	LOC103469120	Tyrosinase-related protein 1b. (549 aa)
	LOC103474215	Synaptotagmin-like 2b. (1682 aa)
	SLC45A4	Solute carrier family 45 member 4. (826 aa)
	LOC103475527	RAB38b, member of RAS oncogene family. (218 aa)
	TYR	Tyrosinase. (542 aa)
	pmel	Premelanosome protein a. (808 aa)
	LOC103460482	Uncharacterized protein. (222 aa)
	oca2	Oculocutaneous albinism II. (840 aa)
	tyrp1	Tyrosinase related protein 1. (525 aa)
	LOC103478639	Solute carrier family 45 member 4b. (784 aa)
	LOC103467913	Premelanosome protein b. (610 aa)
	LOC103478627	Pentaxin. (219 aa)
	ctns	Cystinosin, lysosomal cystine transporter. (419 aa)
	tyr	Tyrosinase. (545 aa)
	RAB38	RAB38, member RAS oncogene family. (212 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103469120	Slc45a1	ENSPREP00000016199	ENSPREP00000006647	Tyrosinase-related protein 1b.	Uncharacterized protein.	0.463
LOC103469120	TYR	ENSPREP00000016199	ENSPREP00000019307	Tyrosinase-related protein 1b.	Tyrosinase.	0.713
LOC103469120	dct	ENSPREP00000016199	ENSPREP00000003234	Tyrosinase-related protein 1b.	Dopachrome tautomerase.	0.917
LOC103469120	gpr143	ENSPREP00000016199	ENSPREP00000001977	Tyrosinase-related protein 1b.	G protein-coupled receptor 143.	0.482
LOC103469120	oca2	ENSPREP00000016199	ENSPREP00000025459	Tyrosinase-related protein 1b.	Oculocutaneous albinism II.	0.700
LOC103469120	pmel	ENSPREP00000016199	ENSPREP00000021188	Tyrosinase-related protein 1b.	Premelanosome protein a.	0.698
LOC103469120	slc45a2	ENSPREP00000016199	ENSPREP00000004737	Tyrosinase-related protein 1b.	Solute carrier family 45 member 2.	0.566
LOC103469120	tyrp1	ENSPREP00000016199	ENSPREP00000027088	Tyrosinase-related protein 1b.	Tyrosinase related protein 1.	0.911
LOC103469428	pmel	ENSPREP00000016339	ENSPREP00000021188	Zgc:91968.	Premelanosome protein a.	0.476
LOC103478639	dct	ENSPREP00000028181	ENSPREP00000003234	Solute carrier family 45 member 4b.	Dopachrome tautomerase.	0.410
RAB38	dct	ENSPREP00000030455	ENSPREP00000003234	RAB38, member RAS oncogene family.	Dopachrome tautomerase.	0.619
RAB38	slc45a2	ENSPREP00000030455	ENSPREP00000004737	RAB38, member RAS oncogene family.	Solute carrier family 45 member 2.	0.460
RAB38	tyrp1	ENSPREP00000030455	ENSPREP00000027088	RAB38, member RAS oncogene family.	Tyrosinase related protein 1.	0.506
SLC45A4	dct	ENSPREP00000017730	ENSPREP00000003234	Solute carrier family 45 member 4.	Dopachrome tautomerase.	0.410
Slc45a1	LOC103469120	ENSPREP00000006647	ENSPREP00000016199	Uncharacterized protein.	Tyrosinase-related protein 1b.	0.463
Slc45a1	TYR	ENSPREP00000006647	ENSPREP00000019307	Uncharacterized protein.	Tyrosinase.	0.501
Slc45a1	dct	ENSPREP00000006647	ENSPREP00000003234	Uncharacterized protein.	Dopachrome tautomerase.	0.505
Slc45a1	oca2	ENSPREP00000006647	ENSPREP00000025459	Uncharacterized protein.	Oculocutaneous albinism II.	0.470
Slc45a1	pmel	ENSPREP00000006647	ENSPREP00000021188	Uncharacterized protein.	Premelanosome protein a.	0.463
Slc45a1	tyr	ENSPREP00000006647	ENSPREP00000030305	Uncharacterized protein.	Tyrosinase.	0.414