(29 nodes) Mitochondrial nucleoid network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tomm6	Translocase of outer mitochondrial membrane 6 homolog (yeast). (64 aa)
	ddx28	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28. (569 aa)
	elac2	ElaC ribonuclease Z 2. (838 aa)
	tfam	Transcription factor A, mitochondrial. (326 aa)
	LOC103460600	DnaJ heat shock protein family (Hsp40) member A3a. (487 aa)
	dbt	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (492 aa)
	lrrc59	Leucine rich repeat containing 59. (377 aa)
	poldip2	Polymerase (DNA-directed), delta interacting protein 2. (377 aa)
	dna2	Uncharacterized protein. (1328 aa)
	dhx30	DEAH (Asp-Glu-Ala-His) box helicase 30. (1083 aa)
	fastkd2	FAST kinase domains 2. (612 aa)
	tfb2m	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (447 aa)
	twnk	Twinkle mtDNA helicase. (721 aa)
	MTERF1	Mitochondrial transcription termination factor 1. (383 aa)
	utp6	UTP6 small subunit processome component. (603 aa)
	LOC103470725	G-rich RNA sequence binding factor 1. (415 aa)
	tufm	Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (446 aa)
	supv3l1	SUV3-like helicase. (760 aa)
	tefm	Transcription elongation factor, mitochondrial. (375 aa)
	LOC103462844	Hexokinase domain containing 1. (907 aa)
	polg	Polymerase (DNA directed), gamma. (1253 aa)
	lonp1	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (984 aa)
	mterf2	Mitochondrial transcription termination factor 2. (375 aa)
	trmt10c	tRNA methyltransferase 10C, mitochondrial RNase P subunit. (505 aa)
	tfb1m	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (352 aa)
	LOC103459140	Uncharacterized protein. (385 aa)
	ssbp1	Single-stranded DNA binding protein 1. (163 aa)
	LOC103464592	Ubiquinol-cytochrome c reductase complex assembly factor 2. (130 aa)
	LOC103476138	Uncharacterized protein. (486 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103459140	fastkd2	ENSPREP00000033313	ENSPREP00000015239	Uncharacterized protein.	FAST kinase domains 2.	0.499
LOC103460600	lonp1	ENSPREP00000005680	ENSPREP00000030554	DnaJ heat shock protein family (Hsp40) member A3a.	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.	0.485
LOC103460600	tufm	ENSPREP00000005680	ENSPREP00000020585	DnaJ heat shock protein family (Hsp40) member A3a.	Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.447
LOC103470725	ddx28	ENSPREP00000019767	ENSPREP00000004087	G-rich RNA sequence binding factor 1.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28.	0.535
LOC103470725	dhx30	ENSPREP00000019767	ENSPREP00000014851	G-rich RNA sequence binding factor 1.	DEAH (Asp-Glu-Ala-His) box helicase 30.	0.483
LOC103470725	fastkd2	ENSPREP00000019767	ENSPREP00000015239	G-rich RNA sequence binding factor 1.	FAST kinase domains 2.	0.448
LOC103470725	supv3l1	ENSPREP00000019767	ENSPREP00000021777	G-rich RNA sequence binding factor 1.	SUV3-like helicase.	0.439
LOC103470725	trmt10c	ENSPREP00000019767	ENSPREP00000032184	G-rich RNA sequence binding factor 1.	tRNA methyltransferase 10C, mitochondrial RNase P subunit.	0.446
LOC103476138	lonp1	ENSPREP00000000247	ENSPREP00000030554	Uncharacterized protein.	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.	0.485
LOC103476138	tufm	ENSPREP00000000247	ENSPREP00000020585	Uncharacterized protein.	Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.447
MTERF1	fastkd2	ENSPREP00000018253	ENSPREP00000015239	Mitochondrial transcription termination factor 1.	FAST kinase domains 2.	0.769
MTERF1	tfb2m	ENSPREP00000018253	ENSPREP00000016054	Mitochondrial transcription termination factor 1.	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.	0.487
dbt	tufm	ENSPREP00000008184	ENSPREP00000020585	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.423
ddx28	LOC103470725	ENSPREP00000004087	ENSPREP00000019767	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28.	G-rich RNA sequence binding factor 1.	0.535
ddx28	dhx30	ENSPREP00000004087	ENSPREP00000014851	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28.	DEAH (Asp-Glu-Ala-His) box helicase 30.	0.664
ddx28	fastkd2	ENSPREP00000004087	ENSPREP00000015239	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28.	FAST kinase domains 2.	0.714
ddx28	lonp1	ENSPREP00000004087	ENSPREP00000030554	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28.	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.	0.418
ddx28	supv3l1	ENSPREP00000004087	ENSPREP00000021777	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28.	SUV3-like helicase.	0.410
ddx28	tfb2m	ENSPREP00000004087	ENSPREP00000016054	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28.	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.	0.597
ddx28	twnk	ENSPREP00000004087	ENSPREP00000016269	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28.	Twinkle mtDNA helicase.	0.406