STRINGSTRING
dbt dbt bckdhb bckdhb mrps36 mrps36 fh fh ENSPREP00000026406 ENSPREP00000026406 suclg2 suclg2 DLST DLST bckdha bckdha ogdh ogdh ENSPREP00000016750 ENSPREP00000016750 idh3g idh3g suclg1 suclg1 LOC103459060 LOC103459060 LOC103466577 LOC103466577 idh3a idh3a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dbtDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (492 aa)
bckdhbBranched chain keto acid dehydrogenase E1 subunit beta. (387 aa)
mrps36Mitochondrial ribosomal protein S36. (110 aa)
fhFumarate hydratase. (499 aa)
ENSPREP00000026406Oxoglutarate dehydrogenase. (353 aa)
suclg2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (428 aa)
DLSTDihydrolipoamide S-succinyltransferase. (436 aa)
bckdha2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (447 aa)
ogdhOxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). (1019 aa)
ENSPREP00000016750Succinate-CoA ligase, ADP-forming, beta subunit. (378 aa)
idh3gIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (389 aa)
suclg1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (337 aa)
LOC103459060Dihydrolipoamide S-succinyltransferase. (433 aa)
LOC103466577Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (362 aa)
idh3aIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (371 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.