(37 nodes) Catalytic step 2 spliceosome network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	crnkl1	Crooked neck pre-mRNA splicing factor 1. (749 aa)
	ENSPREP00000023437	Uncharacterized protein. (97 aa)
	LOC103479458	Uncharacterized protein. (851 aa)
	dhx35	DEAH-box helicase 35. (699 aa)
	snw1	SNW domain containing 1. (536 aa)
	ppwd1	Peptidylprolyl isomerase domain and WD repeat containing 1. (632 aa)
	ENSPREP00000029432	Uncharacterized protein. (223 aa)
	wdr25	WD_REPEATS_REGION domain-containing protein. (228 aa)
	cwc15	CWC15 spliceosome associated protein homolog. (238 aa)
	sart3	Spliceosome associated factor 3, U4/U6 recycling protein. (947 aa)
	EFL1	Elongation factor like GTPase 1. (1106 aa)
	dhx38	DEAH (Asp-Glu-Ala-His) box polypeptide 38. (1229 aa)
	wdr83	WD repeat domain containing 83. (426 aa)
	ppie	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (301 aa)
	ppil1	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
	cdc40	Cell division cycle 40 homolog (S. cerevisiae). (581 aa)
	prpf4b	Pre-mRNA processing factor 4Bb. (984 aa)
	srrm1	Serine/arginine repetitive matrix 1. (839 aa)
	mtrex	Mtr4 exosome RNA helicase. (1053 aa)
	rbm22	RNA binding motif protein 22. (426 aa)
	cwc22	CWC22 spliceosome associated protein homolog. (854 aa)
	snrnp40	Small nuclear ribonucleoprotein 40 (U5). (347 aa)
	LOC103460651	Cwf21 domain-containing protein. (965 aa)
	DDX41	DEAD-box helicase 41. (614 aa)
	ppil3	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (158 aa)
	xab2	XPA binding protein 2. (912 aa)
	ddx23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23. (805 aa)
	aqr	Aquarius intron-binding spliceosomal factor. (1325 aa)
	LOC103480306	RRM domain-containing protein. (363 aa)
	ENSPREP00000012190	G patch domain containing 1. (769 aa)
	EFTUD2	Elongation factor Tu GTP binding domain containing 2. (389 aa)
	ENSPREP00000012415	EFG_C domain-containing protein. (178 aa)
	snrnp200	Small nuclear ribonucleoprotein 200 (U5). (2136 aa)
	rbmx	RNA binding motif protein X-linked. (383 aa)
	ess2	Ess-2 splicing factor homolog. (479 aa)
	mthfsd	Methenyltetrahydrofolate synthetase domain containing. (503 aa)
	LOC103479278	Cactin. (851 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX41	ENSPREP00000012190	ENSPREP00000007803	ENSPREP00000012190	DEAD-box helicase 41.	G patch domain containing 1.	0.631
DDX41	ENSPREP00000029432	ENSPREP00000007803	ENSPREP00000029432	DEAD-box helicase 41.	Uncharacterized protein.	0.617
DDX41	cdc40	ENSPREP00000007803	ENSPREP00000003161	DEAD-box helicase 41.	Cell division cycle 40 homolog (S. cerevisiae).	0.680
DDX41	cwc22	ENSPREP00000007803	ENSPREP00000006247	DEAD-box helicase 41.	CWC22 spliceosome associated protein homolog.	0.677
DDX41	ddx23	ENSPREP00000007803	ENSPREP00000010375	DEAD-box helicase 41.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	0.519
DDX41	dhx35	ENSPREP00000007803	ENSPREP00000026925	DEAD-box helicase 41.	DEAH-box helicase 35.	0.671
DDX41	dhx38	ENSPREP00000007803	ENSPREP00000034266	DEAD-box helicase 41.	DEAH (Asp-Glu-Ala-His) box polypeptide 38.	0.730
DDX41	mtrex	ENSPREP00000007803	ENSPREP00000004435	DEAD-box helicase 41.	Mtr4 exosome RNA helicase.	0.666
DDX41	ppie	ENSPREP00000007803	ENSPREP00000002091	DEAD-box helicase 41.	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.	0.547
DDX41	ppil1	ENSPREP00000007803	ENSPREP00000002465	DEAD-box helicase 41.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.692
DDX41	ppil3	ENSPREP00000007803	ENSPREP00000008198	DEAD-box helicase 41.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.676
DDX41	ppwd1	ENSPREP00000007803	ENSPREP00000027276	DEAD-box helicase 41.	Peptidylprolyl isomerase domain and WD repeat containing 1.	0.853
DDX41	srrm1	ENSPREP00000007803	ENSPREP00000003793	DEAD-box helicase 41.	Serine/arginine repetitive matrix 1.	0.676
DDX41	wdr25	ENSPREP00000007803	ENSPREP00000029451	DEAD-box helicase 41.	WD_REPEATS_REGION domain-containing protein.	0.617
EFL1	ENSPREP00000029432	ENSPREP00000032600	ENSPREP00000029432	Elongation factor like GTPase 1.	Uncharacterized protein.	0.579
EFL1	LOC103460651	ENSPREP00000032600	ENSPREP00000007743	Elongation factor like GTPase 1.	Cwf21 domain-containing protein.	0.565
EFL1	aqr	ENSPREP00000032600	ENSPREP00000010608	Elongation factor like GTPase 1.	Aquarius intron-binding spliceosomal factor.	0.699
EFL1	cdc40	ENSPREP00000032600	ENSPREP00000003161	Elongation factor like GTPase 1.	Cell division cycle 40 homolog (S. cerevisiae).	0.579
EFL1	crnkl1	ENSPREP00000032600	ENSPREP00000018631	Elongation factor like GTPase 1.	Crooked neck pre-mRNA splicing factor 1.	0.767
EFL1	cwc15	ENSPREP00000032600	ENSPREP00000032374	Elongation factor like GTPase 1.	CWC15 spliceosome associated protein homolog.	0.730