(17 nodes) Presynaptic active zone cytoplasmic component network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPREP00000008454	C2 domain-containing protein. (216 aa)
	UNC13C	Unc-13 homolog C. (2664 aa)
	Unc13b	Uncharacterized protein. (3189 aa)
	LOC103459282	ELKS/RAB6-interacting/CAST family member 1. (1157 aa)
	ENSPREP00000005821	C2 domain-containing protein. (318 aa)
	ENSPREP00000005740	PDZ domain-containing protein. (394 aa)
	LOC103469794	Uncharacterized protein. (1517 aa)
	rims4	Regulating synaptic membrane exocytosis 4. (271 aa)
	LOC103472178	Regulating synaptic membrane exocytosis 3. (323 aa)
	ERC2	Uncharacterized protein. (669 aa)
	LOC103479452	Unc-13 homolog A. (1870 aa)
	RIMS2	Regulating synaptic membrane exocytosis 2. (1303 aa)
	erc1	ELKS/RAB6-interacting/CAST family member 1a. (1115 aa)
	LOC103472577	Uncharacterized protein. (1105 aa)
	rims1	Regulating synaptic membrane exocytosis 1a. (1422 aa)
	unc13a	Uncharacterized protein. (1552 aa)
	erc2	ELKS/RAB6-interacting/CAST family member 2. (1137 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000005740	ENSPREP00000005821	ENSPREP00000005740	ENSPREP00000005821	PDZ domain-containing protein.	C2 domain-containing protein.	0.895
ENSPREP00000005740	ENSPREP00000008454	ENSPREP00000005740	ENSPREP00000008454	PDZ domain-containing protein.	C2 domain-containing protein.	0.605
ENSPREP00000005740	ERC2	ENSPREP00000005740	ENSPREP00000028126	PDZ domain-containing protein.	Uncharacterized protein.	0.409
ENSPREP00000005740	LOC103459282	ENSPREP00000005740	ENSPREP00000006679	PDZ domain-containing protein.	ELKS/RAB6-interacting/CAST family member 1.	0.409
ENSPREP00000005740	LOC103469794	ENSPREP00000005740	ENSPREP00000003533	PDZ domain-containing protein.	Uncharacterized protein.	0.605
ENSPREP00000005740	LOC103472178	ENSPREP00000005740	ENSPREP00000031671	PDZ domain-containing protein.	Regulating synaptic membrane exocytosis 3.	0.764
ENSPREP00000005740	LOC103479452	ENSPREP00000005740	ENSPREP00000026194	PDZ domain-containing protein.	Unc-13 homolog A.	0.605
ENSPREP00000005740	UNC13C	ENSPREP00000005740	ENSPREP00000008426	PDZ domain-containing protein.	Unc-13 homolog C.	0.605
ENSPREP00000005740	Unc13b	ENSPREP00000005740	ENSPREP00000008315	PDZ domain-containing protein.	Uncharacterized protein.	0.605
ENSPREP00000005740	erc1	ENSPREP00000005740	ENSPREP00000023527	PDZ domain-containing protein.	ELKS/RAB6-interacting/CAST family member 1a.	0.409
ENSPREP00000005740	erc2	ENSPREP00000005740	ENSPREP00000012454	PDZ domain-containing protein.	ELKS/RAB6-interacting/CAST family member 2.	0.409
ENSPREP00000005740	rims4	ENSPREP00000005740	ENSPREP00000033147	PDZ domain-containing protein.	Regulating synaptic membrane exocytosis 4.	0.742
ENSPREP00000005740	unc13a	ENSPREP00000005740	ENSPREP00000012463	PDZ domain-containing protein.	Uncharacterized protein.	0.605
ENSPREP00000005821	ENSPREP00000005740	ENSPREP00000005821	ENSPREP00000005740	C2 domain-containing protein.	PDZ domain-containing protein.	0.895
ENSPREP00000005821	ENSPREP00000008454	ENSPREP00000005821	ENSPREP00000008454	C2 domain-containing protein.	C2 domain-containing protein.	0.605
ENSPREP00000005821	ERC2	ENSPREP00000005821	ENSPREP00000028126	C2 domain-containing protein.	Uncharacterized protein.	0.409
ENSPREP00000005821	LOC103459282	ENSPREP00000005821	ENSPREP00000006679	C2 domain-containing protein.	ELKS/RAB6-interacting/CAST family member 1.	0.409
ENSPREP00000005821	LOC103469794	ENSPREP00000005821	ENSPREP00000003533	C2 domain-containing protein.	Uncharacterized protein.	0.605
ENSPREP00000005821	LOC103479452	ENSPREP00000005821	ENSPREP00000026194	C2 domain-containing protein.	Unc-13 homolog A.	0.605
ENSPREP00000005821	UNC13C	ENSPREP00000005821	ENSPREP00000008426	C2 domain-containing protein.	Unc-13 homolog C.	0.605