(10 nodes) JAB1/MPN/MOV34 metalloenzyme domain network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	stambpl1	STAM binding protein-like 1. (410 aa)
	Brcc3	BRCA1/BRCA2-containing complex, subunit 3. (251 aa)
	eif3f	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (273 aa)
	cops5	COP9 signalosome subunit 5. (338 aa)
	psmd14	Proteasome 26S subunit, non-ATPase 14. (310 aa)
	mysm1	Myb-like, SWIRM and MPN domains 1. (847 aa)
	prpf8	Pre-mRNA processing factor 8. (2358 aa)
	psmd7	Proteasome 26S subunit, non-ATPase 7. (330 aa)
	COPS6	COP9 signalosome subunit 6. (316 aa)
	mpnd	MPN domain containing. (474 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Brcc3	psmd7	ENSPREP00000029026	ENSPREP00000023246	BRCA1/BRCA2-containing complex, subunit 3.	Proteasome 26S subunit, non-ATPase 7.	0.968
COPS6	cops5	ENSPREP00000020740	ENSPREP00000029721	COP9 signalosome subunit 6.	COP9 signalosome subunit 5.	0.998
COPS6	eif3f	ENSPREP00000020740	ENSPREP00000029536	COP9 signalosome subunit 6.	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.526
COPS6	mysm1	ENSPREP00000020740	ENSPREP00000031373	COP9 signalosome subunit 6.	Myb-like, SWIRM and MPN domains 1.	0.564
COPS6	psmd14	ENSPREP00000020740	ENSPREP00000029743	COP9 signalosome subunit 6.	Proteasome 26S subunit, non-ATPase 14.	0.528
COPS6	psmd7	ENSPREP00000020740	ENSPREP00000023246	COP9 signalosome subunit 6.	Proteasome 26S subunit, non-ATPase 7.	0.473
cops5	COPS6	ENSPREP00000029721	ENSPREP00000020740	COP9 signalosome subunit 5.	COP9 signalosome subunit 6.	0.998
cops5	eif3f	ENSPREP00000029721	ENSPREP00000029536	COP9 signalosome subunit 5.	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.694
cops5	mpnd	ENSPREP00000029721	ENSPREP00000014470	COP9 signalosome subunit 5.	MPN domain containing.	0.436
cops5	mysm1	ENSPREP00000029721	ENSPREP00000031373	COP9 signalosome subunit 5.	Myb-like, SWIRM and MPN domains 1.	0.539
cops5	prpf8	ENSPREP00000029721	ENSPREP00000032359	COP9 signalosome subunit 5.	Pre-mRNA processing factor 8.	0.455
cops5	psmd14	ENSPREP00000029721	ENSPREP00000029743	COP9 signalosome subunit 5.	Proteasome 26S subunit, non-ATPase 14.	0.690
cops5	psmd7	ENSPREP00000029721	ENSPREP00000023246	COP9 signalosome subunit 5.	Proteasome 26S subunit, non-ATPase 7.	0.876
eif3f	COPS6	ENSPREP00000029536	ENSPREP00000020740	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	COP9 signalosome subunit 6.	0.526
eif3f	cops5	ENSPREP00000029536	ENSPREP00000029721	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	COP9 signalosome subunit 5.	0.694
eif3f	mpnd	ENSPREP00000029536	ENSPREP00000014470	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	MPN domain containing.	0.490
eif3f	mysm1	ENSPREP00000029536	ENSPREP00000031373	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Myb-like, SWIRM and MPN domains 1.	0.565
eif3f	prpf8	ENSPREP00000029536	ENSPREP00000032359	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Pre-mRNA processing factor 8.	0.424
eif3f	psmd14	ENSPREP00000029536	ENSPREP00000029743	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Proteasome 26S subunit, non-ATPase 14.	0.605
mpnd	cops5	ENSPREP00000014470	ENSPREP00000029721	MPN domain containing.	COP9 signalosome subunit 5.	0.436