(28 nodes) Spectrin repeat network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sptbn4	Spectrin, beta, non-erythrocytic 4b. (1946 aa)
	actn1	Actinin, alpha 1. (912 aa)
	Trio	Trio Rho guanine nucleotide exchange factor a. (1516 aa)
	Kalrn	Kalirin RhoGEF kinase a. (1623 aa)
	ENSPREP00000023360	KASH domain-containing protein. (473 aa)
	ENSPREP00000023260	KASH domain-containing protein. (810 aa)
	dmd	Dystrophin. (1180 aa)
	ENSPREP00000021492	Uncharacterized protein. (350 aa)
	LOC103476834	Uncharacterized protein. (745 aa)
	LOC103458402	Spectrin beta chain; Belongs to the spectrin family. (2088 aa)
	syne3	Spectrin repeat containing, nuclear envelope family member 3. (874 aa)
	ENSPREP00000018112	Uncharacterized protein. (369 aa)
	ENSPREP00000018081	PH_9 domain-containing protein. (637 aa)
	LOC103476183	PH domain-containing protein. (1567 aa)
	drp2	Dystrophin related protein 2. (877 aa)
	LOC103476717	Actinin, alpha 2b. (894 aa)
	LOC103478369	Uncharacterized protein. (3064 aa)
	actn3	Actinin alpha 3b. (897 aa)
	utrn	Uncharacterized protein. (972 aa)
	ENSPREP00000005618	Uncharacterized protein. (1359 aa)
	ENSPREP00000005674	Uncharacterized protein. (502 aa)
	ENSPREP00000006087	KASH domain-containing protein. (885 aa)
	LOC103471729	Spectrin beta chain; Belongs to the spectrin family. (2335 aa)
	ENSPREP00000010180	EF-hand domain-containing protein. (611 aa)
	sptan1	Spectrin alpha, non-erythrocytic 1. (2568 aa)
	LOC103475822	Spectrin beta chain; Belongs to the spectrin family. (2375 aa)
	DST	Dystonin. (5116 aa)
	ACTN4	Actinin alpha 4. (898 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN4	ENSPREP00000018081	ENSPREP00000030255	ENSPREP00000018081	Actinin alpha 4.	PH_9 domain-containing protein.	0.895
ACTN4	ENSPREP00000018112	ENSPREP00000030255	ENSPREP00000018112	Actinin alpha 4.	Uncharacterized protein.	0.841
ACTN4	actn1	ENSPREP00000030255	ENSPREP00000027161	Actinin alpha 4.	Actinin, alpha 1.	0.900
DST	ENSPREP00000005674	ENSPREP00000033017	ENSPREP00000005674	Dystonin.	Uncharacterized protein.	0.411
DST	sptan1	ENSPREP00000033017	ENSPREP00000010216	Dystonin.	Spectrin alpha, non-erythrocytic 1.	0.491
ENSPREP00000005618	ENSPREP00000005674	ENSPREP00000005618	ENSPREP00000005674	Uncharacterized protein.	Uncharacterized protein.	0.899
ENSPREP00000005618	drp2	ENSPREP00000005618	ENSPREP00000016814	Uncharacterized protein.	Dystrophin related protein 2.	0.796
ENSPREP00000005618	utrn	ENSPREP00000005618	ENSPREP00000005306	Uncharacterized protein.	Uncharacterized protein.	0.892
ENSPREP00000005674	DST	ENSPREP00000005674	ENSPREP00000033017	Uncharacterized protein.	Dystonin.	0.411
ENSPREP00000005674	ENSPREP00000005618	ENSPREP00000005674	ENSPREP00000005618	Uncharacterized protein.	Uncharacterized protein.	0.899
ENSPREP00000005674	ENSPREP00000010180	ENSPREP00000005674	ENSPREP00000010180	Uncharacterized protein.	EF-hand domain-containing protein.	0.733
ENSPREP00000005674	ENSPREP00000018081	ENSPREP00000005674	ENSPREP00000018081	Uncharacterized protein.	PH_9 domain-containing protein.	0.741
ENSPREP00000005674	ENSPREP00000018112	ENSPREP00000005674	ENSPREP00000018112	Uncharacterized protein.	Uncharacterized protein.	0.665
ENSPREP00000005674	dmd	ENSPREP00000005674	ENSPREP00000021787	Uncharacterized protein.	Dystrophin.	0.899
ENSPREP00000005674	drp2	ENSPREP00000005674	ENSPREP00000016814	Uncharacterized protein.	Dystrophin related protein 2.	0.882
ENSPREP00000005674	utrn	ENSPREP00000005674	ENSPREP00000005306	Uncharacterized protein.	Uncharacterized protein.	0.900
ENSPREP00000010180	ENSPREP00000005674	ENSPREP00000010180	ENSPREP00000005674	EF-hand domain-containing protein.	Uncharacterized protein.	0.733
ENSPREP00000010180	LOC103476717	ENSPREP00000010180	ENSPREP00000014912	EF-hand domain-containing protein.	Actinin, alpha 2b.	0.515
ENSPREP00000010180	LOC103476834	ENSPREP00000010180	ENSPREP00000021270	EF-hand domain-containing protein.	Uncharacterized protein.	0.473
ENSPREP00000010180	sptan1	ENSPREP00000010180	ENSPREP00000010216	EF-hand domain-containing protein.	Spectrin alpha, non-erythrocytic 1.	0.491