(36 nodes) Four-helical cytokine-like, core network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Clcf1	Cardiotrophin-like cytokine factor 1. (182 aa)
	prl	Prolactin 2. (284 aa)
	LOC103481991	Uncharacterized protein. (199 aa)
	LOC103472861	Uncharacterized protein. (243 aa)
	LOC108166887	Uncharacterized protein. (207 aa)
	LOC103474759	Somatolactin alpha. (231 aa)
	LOC103464868	Interleukin 19 like. (200 aa)
	il10	Interleukin 10. (229 aa)
	ENSPREP00000005271	Uncharacterized protein. (210 aa)
	Kitlg	Kit ligand a. (201 aa)
	LOC103474728	Interleukin-12 subunit alpha; Belongs to the IL-6 superfamily. (187 aa)
	ENSPREP00000002941	Uncharacterized protein. (156 aa)
	LOC103479630	Zmp:0000001127. (204 aa)
	ENSPREP00000001160	Uncharacterized protein. (196 aa)
	ENSPREP00000007537	Uncharacterized protein. (201 aa)
	ENSPREP00000007555	Uncharacterized protein. (216 aa)
	ifng1	Uncharacterized protein. (202 aa)
	ENSPREP00000007766	Uncharacterized protein. (171 aa)
	ENSPREP00000007795	Uncharacterized protein. (199 aa)
	ENSPREP00000009704	Uncharacterized protein. (133 aa)
	ENSPREP00000009963	Interleukin; Belongs to the IL-15/IL-21 family. (96 aa)
	ENSPREP00000012567	Ciliary neurotrophic factor. (184 aa)
	LOC103478037	Interleukin 11a. (200 aa)
	ENSPREP00000016463	Uncharacterized protein. (111 aa)
	LOC108167267	Uncharacterized protein. (184 aa)
	ENSPREP00000017275	Uncharacterized protein. (199 aa)
	LOC103459420	Uncharacterized protein. (253 aa)
	LOC103468295	Prolactin. (248 aa)
	ENSPREP00000017840	Uncharacterized protein. (175 aa)
	ENSPREP00000018105	Uncharacterized protein. (204 aa)
	LOC103469032	Chorionic somatomammotropin hormone 1. (204 aa)
	LOC103473748	IL-6 subfamily cytokine M17. (223 aa)
	epo	Erythropoietin; Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Belongs to the EPO/TPO family. (186 aa)
	LOC103467541	Colony stimulating factor 1b (macrophage). (266 aa)
	ENSPREP00000024600	Uncharacterized protein. (191 aa)
	ENSPREP00000024622	Uncharacterized protein. (189 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000007795	il10	ENSPREP00000007795	ENSPREP00000005577	Uncharacterized protein.	Interleukin 10.	0.470
ENSPREP00000009963	il10	ENSPREP00000009963	ENSPREP00000005577	Interleukin; Belongs to the IL-15/IL-21 family.	Interleukin 10.	0.660
ENSPREP00000016463	LOC108167267	ENSPREP00000016463	ENSPREP00000016520	Uncharacterized protein.	Uncharacterized protein.	0.492
ENSPREP00000017840	il10	ENSPREP00000017840	ENSPREP00000005577	Uncharacterized protein.	Interleukin 10.	0.523
ENSPREP00000018105	LOC108167267	ENSPREP00000018105	ENSPREP00000016520	Uncharacterized protein.	Uncharacterized protein.	0.577
Kitlg	LOC103459420	ENSPREP00000004205	ENSPREP00000017449	Kit ligand a.	Uncharacterized protein.	0.901
Kitlg	LOC103478037	ENSPREP00000004205	ENSPREP00000013504	Kit ligand a.	Interleukin 11a.	0.438
LOC103459420	Kitlg	ENSPREP00000017449	ENSPREP00000004205	Uncharacterized protein.	Kit ligand a.	0.901
LOC103464868	il10	ENSPREP00000005585	ENSPREP00000005577	Interleukin 19 like.	Interleukin 10.	0.555
LOC103467541	il10	ENSPREP00000023788	ENSPREP00000005577	Colony stimulating factor 1b (macrophage).	Interleukin 10.	0.551
LOC103468295	LOC103469032	ENSPREP00000017818	ENSPREP00000018522	Prolactin.	Chorionic somatomammotropin hormone 1.	0.879
LOC103468295	LOC103474759	ENSPREP00000017818	ENSPREP00000006870	Prolactin.	Somatolactin alpha.	0.740
LOC103468295	LOC103478037	ENSPREP00000017818	ENSPREP00000013504	Prolactin.	Interleukin 11a.	0.496
LOC103468295	prl	ENSPREP00000017818	ENSPREP00000026254	Prolactin.	Prolactin 2.	0.903
LOC103469032	LOC103468295	ENSPREP00000018522	ENSPREP00000017818	Chorionic somatomammotropin hormone 1.	Prolactin.	0.879
LOC103469032	prl	ENSPREP00000018522	ENSPREP00000026254	Chorionic somatomammotropin hormone 1.	Prolactin 2.	0.772
LOC103474759	LOC103468295	ENSPREP00000006870	ENSPREP00000017818	Somatolactin alpha.	Prolactin.	0.740
LOC103474759	prl	ENSPREP00000006870	ENSPREP00000026254	Somatolactin alpha.	Prolactin 2.	0.725
LOC103478037	Kitlg	ENSPREP00000013504	ENSPREP00000004205	Interleukin 11a.	Kit ligand a.	0.438
LOC103478037	LOC103468295	ENSPREP00000013504	ENSPREP00000017818	Interleukin 11a.	Prolactin.	0.496