(35 nodes) EGF-like, conserved site network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103473440	Notch receptor 1a. (2478 aa)
	LOC103458084	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1243 aa)
	LOC103462246	Si:ch211-186j3.6; Cadherins are calcium-dependent cell adhesion proteins. (2942 aa)
	svep1	Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1. (3626 aa)
	celsr2	Cadherin, EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (3043 aa)
	ENSPREP00000008634	Uncharacterized protein. (690 aa)
	LOC103468742	Notch receptor 3. (2442 aa)
	notch1	Notch receptor 1b. (2491 aa)
	dll3	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (700 aa)
	jag1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1217 aa)
	slit2	Slit homolog 2 (Drosophila). (1578 aa)
	LOC103463625	Notch receptor 2. (2489 aa)
	MEGF11	Multiple EGF like domains 11. (1026 aa)
	megf11	Multiple EGF-like-domains 11. (1063 aa)
	LOC103464045	Si:dkey-235d18.5. (701 aa)
	LOC103471805	Slit homolog 3 (Drosophila). (1466 aa)
	LOC103463303	Crumbs cell polarity complex component 1. (1334 aa)
	Dlk2	Delta-like 2 homolog (Drosophila). (340 aa)
	crb2	Crumbs cell polarity complex component 2b. (1343 aa)
	LOC103473166	Uncharacterized protein. (1465 aa)
	LOC103473495	Uncharacterized protein. (1073 aa)
	dll4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (735 aa)
	sned1	Sushi, nidogen and EGF-like domains 1. (1261 aa)
	jag2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1190 aa)
	LOC103464115	Fibrillin 2b. (2647 aa)
	dner	Delta/notch-like EGF repeat containing. (772 aa)
	LOC103477590	Si:dkey-22o22.2; Cadherins are calcium-dependent cell adhesion proteins. (2937 aa)
	ltbp2	Uncharacterized protein. (1978 aa)
	LOC103458504	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (694 aa)
	slit1	Slit homolog 1a (Drosophila). (1505 aa)
	LOC103466206	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (2795 aa)
	LOC103470154	Slit homolog 1b (Drosophila). (1531 aa)
	LOC103470192	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (748 aa)
	ENSPREP00000033301	Uncharacterized protein. (756 aa)
	LTBP3	Latent transforming growth factor beta binding protein 3. (1235 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000008634	ENSPREP00000033301	ENSPREP00000008634	ENSPREP00000033301	Uncharacterized protein.	Uncharacterized protein.	0.647
ENSPREP00000033301	ENSPREP00000008634	ENSPREP00000033301	ENSPREP00000008634	Uncharacterized protein.	Uncharacterized protein.	0.647
ENSPREP00000033301	LOC103458084	ENSPREP00000033301	ENSPREP00000003595	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.487
ENSPREP00000033301	LOC103458504	ENSPREP00000033301	ENSPREP00000028811	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.413
ENSPREP00000033301	LOC103470192	ENSPREP00000033301	ENSPREP00000031612	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.413
ENSPREP00000033301	dll3	ENSPREP00000033301	ENSPREP00000009724	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.413
ENSPREP00000033301	dll4	ENSPREP00000033301	ENSPREP00000020386	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.413
ENSPREP00000033301	jag1	ENSPREP00000033301	ENSPREP00000010508	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.487
ENSPREP00000033301	jag2	ENSPREP00000033301	ENSPREP00000023176	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.487
LOC103458084	ENSPREP00000033301	ENSPREP00000003595	ENSPREP00000033301	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.487
LOC103458084	LOC103463625	ENSPREP00000003595	ENSPREP00000013783	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 2.	0.946
LOC103458084	LOC103468742	ENSPREP00000003595	ENSPREP00000008958	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 3.	0.947
LOC103458084	LOC103473440	ENSPREP00000003595	ENSPREP00000002570	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 1a.	0.976
LOC103458084	jag1	ENSPREP00000003595	ENSPREP00000010508	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.902
LOC103458084	notch1	ENSPREP00000003595	ENSPREP00000009635	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 1b.	0.976
LOC103458504	ENSPREP00000033301	ENSPREP00000028811	ENSPREP00000033301	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.413
LOC103458504	LOC103463625	ENSPREP00000028811	ENSPREP00000013783	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 2.	0.827
LOC103458504	LOC103468742	ENSPREP00000028811	ENSPREP00000008958	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 3.	0.786
LOC103458504	LOC103473440	ENSPREP00000028811	ENSPREP00000002570	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 1a.	0.896
LOC103458504	notch1	ENSPREP00000028811	ENSPREP00000009635	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 1b.	0.896