(23 nodes) Double-stranded RNA-binding domain network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103464540	Interleukin enhancer binding factor 3a. (862 aa)
	dus2	Dihydrouridine synthase 2. (482 aa)
	stau1	Staufen double-stranded RNA binding protein 1. (696 aa)
	prkra	Protein kinase, interferon-inducible double stranded RNA dependent activator. (301 aa)
	adarb2	Adenosine deaminase RNA specific B2 (inactive). (766 aa)
	adad1	Adenosine deaminase domain containing 1 (testis-specific). (536 aa)
	tarbp2	RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] (345 aa)
	LOC103477270	Uncharacterized protein. (689 aa)
	ENSPREP00000011628	Uncharacterized protein. (564 aa)
	strbp	Spermatid perinuclear RNA binding protein. (747 aa)
	dicer1	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. (1860 aa)
	LOC103470702	Uncharacterized protein. (672 aa)
	ilf3	Interleukin enhancer binding factor 3b. (825 aa)
	a1cf	Apobec1 complementation factor. (614 aa)
	drosha	Drosha ribonuclease III. (1312 aa)
	ADARB2	Uncharacterized protein. (680 aa)
	dhx9	DEAH (Asp-Glu-Ala-His) box helicase 9. (1216 aa)
	dgcr8	DGCR8 microprocessor complex subunit. (787 aa)
	LOC103477529	Uncharacterized protein. (749 aa)
	LOC103477214	Uncharacterized protein. (951 aa)
	stau2	Staufen double-stranded RNA binding protein 2. (713 aa)
	adar	Adenosine deaminase RNA specific. (1358 aa)
	LOC103460190	Adenosine deaminase RNA specific B1b. (727 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000011628	adar	ENSPREP00000011628	ENSPREP00000025832	Uncharacterized protein.	Adenosine deaminase RNA specific.	0.547
ENSPREP00000011628	dhx9	ENSPREP00000011628	ENSPREP00000028546	Uncharacterized protein.	DEAH (Asp-Glu-Ala-His) box helicase 9.	0.429
ENSPREP00000011628	dicer1	ENSPREP00000011628	ENSPREP00000017960	Uncharacterized protein.	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	0.413
ENSPREP00000011628	ilf3	ENSPREP00000011628	ENSPREP00000020174	Uncharacterized protein.	Interleukin enhancer binding factor 3b.	0.633
ENSPREP00000011628	prkra	ENSPREP00000011628	ENSPREP00000008305	Uncharacterized protein.	Protein kinase, interferon-inducible double stranded RNA dependent activator.	0.483
ENSPREP00000011628	tarbp2	ENSPREP00000011628	ENSPREP00000011475	Uncharacterized protein.	RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]	0.483
LOC103477270	adar	ENSPREP00000011565	ENSPREP00000025832	Uncharacterized protein.	Adenosine deaminase RNA specific.	0.547
LOC103477270	dhx9	ENSPREP00000011565	ENSPREP00000028546	Uncharacterized protein.	DEAH (Asp-Glu-Ala-His) box helicase 9.	0.429
LOC103477270	dicer1	ENSPREP00000011565	ENSPREP00000017960	Uncharacterized protein.	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	0.413
LOC103477270	ilf3	ENSPREP00000011565	ENSPREP00000020174	Uncharacterized protein.	Interleukin enhancer binding factor 3b.	0.633
LOC103477270	prkra	ENSPREP00000011565	ENSPREP00000008305	Uncharacterized protein.	Protein kinase, interferon-inducible double stranded RNA dependent activator.	0.483
LOC103477270	tarbp2	ENSPREP00000011565	ENSPREP00000011475	Uncharacterized protein.	RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]	0.483
adar	ENSPREP00000011628	ENSPREP00000025832	ENSPREP00000011628	Adenosine deaminase RNA specific.	Uncharacterized protein.	0.547
adar	LOC103477270	ENSPREP00000025832	ENSPREP00000011565	Adenosine deaminase RNA specific.	Uncharacterized protein.	0.547
adar	dhx9	ENSPREP00000025832	ENSPREP00000028546	Adenosine deaminase RNA specific.	DEAH (Asp-Glu-Ala-His) box helicase 9.	0.609
adar	dicer1	ENSPREP00000025832	ENSPREP00000017960	Adenosine deaminase RNA specific.	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	0.685
adar	drosha	ENSPREP00000025832	ENSPREP00000032952	Adenosine deaminase RNA specific.	Drosha ribonuclease III.	0.496
adar	ilf3	ENSPREP00000025832	ENSPREP00000020174	Adenosine deaminase RNA specific.	Interleukin enhancer binding factor 3b.	0.452
dgcr8	dicer1	ENSPREP00000027922	ENSPREP00000017960	DGCR8 microprocessor complex subunit.	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	0.928
dgcr8	drosha	ENSPREP00000027922	ENSPREP00000032952	DGCR8 microprocessor complex subunit.	Drosha ribonuclease III.	0.995