(40 nodes) Ubiquitin-associated domain network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mark2	Non-specific serine/threonine protein kinase. (777 aa)
	LOC103469285	Trinucleotide repeat containing adaptor 6C1. (1769 aa)
	lats2	Large tumor suppressor kinase 2. (1157 aa)
	UBAP1L	Ubiquitin associated protein 1 like. (409 aa)
	LOC103471315	Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (204 aa)
	vps13d	Vacuolar protein sorting 13 homolog D. (3861 aa)
	tnk2	Tyrosine kinase, non-receptor, 2b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1200 aa)
	LOC103464527	DNA-damage inducible protein 2. (859 aa)
	mark3	Non-specific serine/threonine protein kinase. (814 aa)
	ubl7	Ubiquitin-like 7b (bone marrow stromal cell-derived). (392 aa)
	ubqln4	Ubiquilin 4. (583 aa)
	ubac1	UBA domain containing 1. (420 aa)
	sik3	SIK family kinase 3. (1358 aa)
	dhx57	DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57. (1421 aa)
	nub1	Negative regulator of ubiquitin-like proteins 1. (587 aa)
	snrk	SNF related kinase a. (760 aa)
	ubac2	UBA domain containing 2. (353 aa)
	LOC103476195	Non-specific serine/threonine protein kinase. (747 aa)
	sqstm1	Sequestosome 1. (500 aa)
	usp5	Ubiquitin carboxyl-terminal hydrolase. (848 aa)
	ubash3b	Ubiquitin associated and SH3 domain containing Bb. (614 aa)
	LOC103476312	Uncharacterized protein. (857 aa)
	usp13	Ubiquitinyl hydrolase 1. (867 aa)
	ubxn1	UBX domain protein 1. (296 aa)
	LOC103468018	Trinucleotide repeat containing adaptor 6C2. (1547 aa)
	RAD23B	RAD23 homolog B, nucleotide excision repair protein. (421 aa)
	herc2	HECT and RLD domain containing E3 ubiquitin protein ligase 2. (4520 aa)
	LOC103472082	Uncharacterized protein. (785 aa)
	MARK1	Non-specific serine/threonine protein kinase. (706 aa)
	mark4	Non-specific serine/threonine protein kinase. (748 aa)
	ubap2l	Ubiquitin associated protein 2-like. (1184 aa)
	LOC103470245	Ubiquitin associated protein 2b. (1166 aa)
	ubap1	Ubiquitin associated protein 1. (455 aa)
	ubap2	Ubiquitin associated protein 2a. (1258 aa)
	tdrd3	Tudor domain containing 3. (786 aa)
	huwe1	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4580 aa)
	cbl	Cbl proto-oncogene, E3 ubiquitin protein ligase. (848 aa)
	sik2	Salt-inducible kinase 2b. (930 aa)
	rnf31	Ring finger protein 31. (1109 aa)
	LOC103459795	Salt-inducible kinase 1. (802 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103464527	RAD23B	ENSPREP00000006068	ENSPREP00000024975	DNA-damage inducible protein 2.	RAD23 homolog B, nucleotide excision repair protein.	0.711
LOC103464527	ubl7	ENSPREP00000006068	ENSPREP00000008628	DNA-damage inducible protein 2.	Ubiquitin-like 7b (bone marrow stromal cell-derived).	0.486
LOC103464527	ubqln4	ENSPREP00000006068	ENSPREP00000008822	DNA-damage inducible protein 2.	Ubiquilin 4.	0.613
LOC103471315	RAD23B	ENSPREP00000003043	ENSPREP00000024975	Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family.	RAD23 homolog B, nucleotide excision repair protein.	0.427
LOC103471315	ubqln4	ENSPREP00000003043	ENSPREP00000008822	Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquilin 4.	0.412
LOC103476312	ubl7	ENSPREP00000022529	ENSPREP00000008628	Uncharacterized protein.	Ubiquitin-like 7b (bone marrow stromal cell-derived).	0.469
LOC103476312	ubqln4	ENSPREP00000022529	ENSPREP00000008822	Uncharacterized protein.	Ubiquilin 4.	0.569
RAD23B	LOC103464527	ENSPREP00000024975	ENSPREP00000006068	RAD23 homolog B, nucleotide excision repair protein.	DNA-damage inducible protein 2.	0.711
RAD23B	LOC103471315	ENSPREP00000024975	ENSPREP00000003043	RAD23 homolog B, nucleotide excision repair protein.	Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family.	0.427
RAD23B	nub1	ENSPREP00000024975	ENSPREP00000014525	RAD23 homolog B, nucleotide excision repair protein.	Negative regulator of ubiquitin-like proteins 1.	0.603
RAD23B	rnf31	ENSPREP00000024975	ENSPREP00000033338	RAD23 homolog B, nucleotide excision repair protein.	Ring finger protein 31.	0.410
RAD23B	sqstm1	ENSPREP00000024975	ENSPREP00000016733	RAD23 homolog B, nucleotide excision repair protein.	Sequestosome 1.	0.531
RAD23B	ubl7	ENSPREP00000024975	ENSPREP00000008628	RAD23 homolog B, nucleotide excision repair protein.	Ubiquitin-like 7b (bone marrow stromal cell-derived).	0.656
RAD23B	ubqln4	ENSPREP00000024975	ENSPREP00000008822	RAD23 homolog B, nucleotide excision repair protein.	Ubiquilin 4.	0.877
RAD23B	ubxn1	ENSPREP00000024975	ENSPREP00000023482	RAD23 homolog B, nucleotide excision repair protein.	UBX domain protein 1.	0.743
RAD23B	usp13	ENSPREP00000024975	ENSPREP00000022602	RAD23 homolog B, nucleotide excision repair protein.	Ubiquitinyl hydrolase 1.	0.687
RAD23B	usp5	ENSPREP00000024975	ENSPREP00000018558	RAD23 homolog B, nucleotide excision repair protein.	Ubiquitin carboxyl-terminal hydrolase.	0.687
cbl	ubl7	ENSPREP00000032775	ENSPREP00000008628	Cbl proto-oncogene, E3 ubiquitin protein ligase.	Ubiquitin-like 7b (bone marrow stromal cell-derived).	0.469
cbl	ubqln4	ENSPREP00000032775	ENSPREP00000008822	Cbl proto-oncogene, E3 ubiquitin protein ligase.	Ubiquilin 4.	0.569
huwe1	ubl7	ENSPREP00000032331	ENSPREP00000008628	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	Ubiquitin-like 7b (bone marrow stromal cell-derived).	0.439