(11 nodes) Thiolase-like network (Poecilia reticulata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	acaa2	Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
	acaa1	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (419 aa)
	scp2	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (572 aa)
	acat2	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (363 aa)
	acat1	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (420 aa)
	LOC103473119	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (577 aa)
	oxsm	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (465 aa)
	hadhb	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (327 aa)
	LOC103456937	Carrier domain-containing protein. (2076 aa)
	LOC103456785	Si:dkey-61p9.11. (2009 aa)
	fasn	Coiled-coil domain containing 57. (2516 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103456785	LOC103473119	ENSPREP00000001717	ENSPREP00000017837	Si:dkey-61p9.11.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.525
LOC103456785	oxsm	ENSPREP00000001717	ENSPREP00000019728	Si:dkey-61p9.11.	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.478
LOC103456937	LOC103473119	ENSPREP00000001701	ENSPREP00000017837	Carrier domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.525
LOC103456937	oxsm	ENSPREP00000001701	ENSPREP00000019728	Carrier domain-containing protein.	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.478
LOC103473119	LOC103456785	ENSPREP00000017837	ENSPREP00000001717	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Si:dkey-61p9.11.	0.525
LOC103473119	LOC103456937	ENSPREP00000017837	ENSPREP00000001701	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Carrier domain-containing protein.	0.525
LOC103473119	acaa1	ENSPREP00000017837	ENSPREP00000006361	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.991
LOC103473119	acaa2	ENSPREP00000017837	ENSPREP00000016912	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.992
LOC103473119	acat1	ENSPREP00000017837	ENSPREP00000015486	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.993
LOC103473119	acat2	ENSPREP00000017837	ENSPREP00000008323	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.996
LOC103473119	fasn	ENSPREP00000017837	ENSPREP00000005709	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Coiled-coil domain containing 57.	0.525
LOC103473119	hadhb	ENSPREP00000017837	ENSPREP00000023429	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family.	0.941
LOC103473119	oxsm	ENSPREP00000017837	ENSPREP00000019728	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.714
LOC103473119	scp2	ENSPREP00000017837	ENSPREP00000006966	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.417
acaa1	LOC103473119	ENSPREP00000006361	ENSPREP00000017837	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.991
acaa1	acaa2	ENSPREP00000006361	ENSPREP00000016912	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.920
acaa1	acat1	ENSPREP00000006361	ENSPREP00000015486	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.925
acaa1	acat2	ENSPREP00000006361	ENSPREP00000008323	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.921
acaa1	scp2	ENSPREP00000006361	ENSPREP00000006966	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.971
acaa2	LOC103473119	ENSPREP00000016912	ENSPREP00000017837	Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.992