(19 nodes) Caspase-like domain superfamily network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103474681	Uncharacterized protein; Belongs to the peptidase C14A family. (386 aa)
	CASP3	Caspase 3; Belongs to the peptidase C14A family. (292 aa)
	ENSPREP00000002255	Uncharacterized protein; Belongs to the peptidase C14A family. (387 aa)
	ENSPREP00000002308	Uncharacterized protein; Belongs to the peptidase C14A family. (388 aa)
	casp2	Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (464 aa)
	cflar	Uncharacterized protein; Belongs to the peptidase C14A family. (433 aa)
	LOC103469935	MALT paracaspase 1. (828 aa)
	LOC103466618	MALT paracaspase 3. (573 aa)
	LOC103459939	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (507 aa)
	ENSPREP00000003888	Uncharacterized protein; Belongs to the peptidase C14A family. (334 aa)
	casp6	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (312 aa)
	LOC108167062	Uncharacterized protein; Belongs to the peptidase C14A family. (224 aa)
	LOC103478932	Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (389 aa)
	LOC103478931	Uncharacterized protein; Belongs to the peptidase C14A family. (444 aa)
	LOC103461041	Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (282 aa)
	casp7	Caspase 7, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (320 aa)
	casp9	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (427 aa)
	LOC103473137	Uncharacterized protein; Belongs to the peptidase C14A family. (250 aa)
	ENSPREP00000018398	MALT paracaspase 2. (715 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP3	LOC103459939	ENSPREP00000001533	ENSPREP00000008346	Caspase 3; Belongs to the peptidase C14A family.	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.965
CASP3	LOC103461041	ENSPREP00000001533	ENSPREP00000000103	Caspase 3; Belongs to the peptidase C14A family.	Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	0.902
CASP3	LOC103478931	ENSPREP00000001533	ENSPREP00000002444	Caspase 3; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.968
CASP3	LOC103478932	ENSPREP00000001533	ENSPREP00000002524	Caspase 3; Belongs to the peptidase C14A family.	Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.953
CASP3	LOC108167062	ENSPREP00000001533	ENSPREP00000002554	Caspase 3; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.957
CASP3	casp2	ENSPREP00000001533	ENSPREP00000015138	Caspase 3; Belongs to the peptidase C14A family.	Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.468
CASP3	casp6	ENSPREP00000001533	ENSPREP00000003415	Caspase 3; Belongs to the peptidase C14A family.	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	0.402
CASP3	casp9	ENSPREP00000001533	ENSPREP00000019950	Caspase 3; Belongs to the peptidase C14A family.	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.970
ENSPREP00000018398	LOC103459939	ENSPREP00000018398	ENSPREP00000008346	MALT paracaspase 2.	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.629
ENSPREP00000018398	LOC103478931	ENSPREP00000018398	ENSPREP00000002444	MALT paracaspase 2.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.629
ENSPREP00000018398	LOC103478932	ENSPREP00000018398	ENSPREP00000002524	MALT paracaspase 2.	Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.534
ENSPREP00000018398	LOC108167062	ENSPREP00000018398	ENSPREP00000002554	MALT paracaspase 2.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.534
LOC103459939	CASP3	ENSPREP00000008346	ENSPREP00000001533	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	Caspase 3; Belongs to the peptidase C14A family.	0.965
LOC103459939	ENSPREP00000018398	ENSPREP00000008346	ENSPREP00000018398	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	MALT paracaspase 2.	0.629
LOC103459939	LOC103461041	ENSPREP00000008346	ENSPREP00000000103	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	0.964
LOC103459939	LOC103466618	ENSPREP00000008346	ENSPREP00000011487	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	MALT paracaspase 3.	0.961
LOC103459939	LOC103469935	ENSPREP00000008346	ENSPREP00000011835	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	MALT paracaspase 1.	0.961
LOC103459939	LOC103473137	ENSPREP00000008346	ENSPREP00000018681	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.964
LOC103459939	LOC103474681	ENSPREP00000008346	ENSPREP00000002342	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.931
LOC103459939	casp2	ENSPREP00000008346	ENSPREP00000015138	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.552