(66 nodes) FERM superfamily, second domain network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	frmd6	FERM domain containing 6. (607 aa)
	ptpn13	Protein tyrosine phosphatase non-receptor type 13. (2569 aa)
	myo7a	Myosin VIIAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2143 aa)
	ptpn3	Protein tyrosine phosphatase non-receptor type 3. (1009 aa)
	epb41l4b	Erythrocyte membrane protein band 4.1 like 4B. (772 aa)
	krit1	KRIT1 ankyrin repeat containing. (739 aa)
	LOC103480677	FERM domain-containing protein. (656 aa)
	epb41l2	Erythrocyte membrane protein band 4.1 like 2. (887 aa)
	plekhh1	Pleckstrin homology domain containing, family H (with MyTH4 domain) member 1. (1425 aa)
	farp2	FERM, RhoGEF and pleckstrin domain protein 2. (1082 aa)
	frmd4a	FERM domain containing 4A. (1097 aa)
	LOC103476307	Myosin VIIAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2194 aa)
	fermt3	Fermitin family member 3b. (645 aa)
	epb41l5	Erythrocyte membrane protein band 4.1 like 5. (762 aa)
	ptpn4	Protein tyrosine phosphatase non-receptor type 4a. (1035 aa)
	fermt1	Fermitin family member 1. (666 aa)
	myo7b	Si:ch73-194h10.2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2175 aa)
	PTPN14	Protein tyrosine phosphatase non-receptor type 14. (1258 aa)
	noc3l	NOC3-like DNA replication regulator. (1039 aa)
	LOC103478268	FERM domain-containing protein. (572 aa)
	LOC103459129	Toll-like receptor 7. (1256 aa)
	LOC103463747	Uncharacterized protein. (2063 aa)
	LOC103471308	FERM and PDZ domain containing 1b. (1706 aa)
	LOC103478950	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1782 aa)
	ENSPREP00000003966	FERM domain-containing protein. (181 aa)
	frmd4b	FERM domain containing 4Bb. (986 aa)
	frmd8	FERM domain containing 8. (402 aa)
	LOC103458733	Myosin X, like 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2070 aa)
	tyk2	Tyrosine-protein kinase. (1153 aa)
	fermt2	Fermitin family member 2. (712 aa)
	LOC103461720	Uncharacterized protein. (1040 aa)
	frmpd3	FERM and PDZ domain containing 3. (1728 aa)
	ptpn21	Protein tyrosine phosphatase non-receptor type 21. (1315 aa)
	LOC103466619	FERM domain containing 5. (573 aa)
	EZR	Ezrin b. (582 aa)
	LOC103458206	Ezrin a. (593 aa)
	jak2	Tyrosine-protein kinase. (1190 aa)
	FRMPD4	FERM and PDZ domain containing 4. (1979 aa)
	ENSPREP00000013494	FERM domain-containing protein. (184 aa)
	LOC103461672	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2095 aa)
	plekhh3	Pleckstrin homology, MyTH4 and FERM domain containing H3. (677 aa)
	nf2	Neurofibromin 2b (merlin). (615 aa)
	ptk2	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family. (878 aa)
	LOC103469946	Tyrosine-protein kinase. (1122 aa)
	mylip	Myosin regulatory light chain interacting protein a. (481 aa)
	tln2	Talin 2b. (2552 aa)
	LOC103460834	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived). (1016 aa)
	LOC103467236	Si:dkey-178k16.1. (1227 aa)
	epb41l1	FERM domain-containing protein. (1325 aa)
	frmd1	FERM domain-containing protein. (531 aa)
	LOC103465525	FERM domain containing 4Ba. (1071 aa)
	frmpd2	FERM and PDZ domain containing 2. (1149 aa)
	LOC103470912	Moesin b. (582 aa)
	msn	Moesin a. (597 aa)
	myo10	Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2040 aa)
	jak1	Tyrosine-protein kinase. (1174 aa)
	ENSPREP00000029577	Erythrocyte membrane protein band 4.1a. (554 aa)
	LOC103457606	Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (994 aa)
	EPB41L3	Erythrocyte membrane protein band 4.1-like 3a. (751 aa)
	epb41l3	Erythrocyte membrane protein band 4.1-like 3b. (847 aa)
	plekhh2	Pleckstrin homology domain containing, family H (with MyTH4 domain) member 2. (1417 aa)
	RDX	Radixin. (581 aa)
	LOC103475221	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (942 aa)
	LOC103472469	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1080 aa)
	ENSPREP00000017779	FERM domain-containing protein. (283 aa)
	frmd3	FERM domain containing 3. (658 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000003966	epb41l4b	ENSPREP00000003966	ENSPREP00000026986	FERM domain-containing protein.	Erythrocyte membrane protein band 4.1 like 4B.	0.407
ENSPREP00000003966	epb41l5	ENSPREP00000003966	ENSPREP00000023604	FERM domain-containing protein.	Erythrocyte membrane protein band 4.1 like 5.	0.421
ENSPREP00000017779	LOC103457606	ENSPREP00000017779	ENSPREP00000028576	FERM domain-containing protein.	Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.504
ENSPREP00000017779	LOC103472469	ENSPREP00000017779	ENSPREP00000017329	FERM domain-containing protein.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.559
ENSPREP00000017779	LOC103475221	ENSPREP00000017779	ENSPREP00000017059	FERM domain-containing protein.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.504
ENSPREP00000017779	ptk2	ENSPREP00000017779	ENSPREP00000014357	FERM domain-containing protein.	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.559
ENSPREP00000029577	epb41l4b	ENSPREP00000029577	ENSPREP00000026986	Erythrocyte membrane protein band 4.1a.	Erythrocyte membrane protein band 4.1 like 4B.	0.407
ENSPREP00000029577	epb41l5	ENSPREP00000029577	ENSPREP00000023604	Erythrocyte membrane protein band 4.1a.	Erythrocyte membrane protein band 4.1 like 5.	0.415
EPB41L3	epb41l4b	ENSPREP00000015047	ENSPREP00000026986	Erythrocyte membrane protein band 4.1-like 3a.	Erythrocyte membrane protein band 4.1 like 4B.	0.407
EPB41L3	epb41l5	ENSPREP00000015047	ENSPREP00000023604	Erythrocyte membrane protein band 4.1-like 3a.	Erythrocyte membrane protein band 4.1 like 5.	0.407
EZR	msn	ENSPREP00000011767	ENSPREP00000030741	Ezrin b.	Moesin a.	0.486
LOC103457606	ENSPREP00000017779	ENSPREP00000028576	ENSPREP00000017779	Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family.	FERM domain-containing protein.	0.504
LOC103457606	LOC103469946	ENSPREP00000028576	ENSPREP00000012332	Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.499
LOC103457606	jak1	ENSPREP00000028576	ENSPREP00000030183	Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.499
LOC103457606	jak2	ENSPREP00000028576	ENSPREP00000013328	Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.499
LOC103457606	tln2	ENSPREP00000028576	ENSPREP00000012606	Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Talin 2b.	0.504
LOC103457606	tyk2	ENSPREP00000028576	ENSPREP00000010019	Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.499
LOC103467236	epb41l4b	ENSPREP00000024537	ENSPREP00000026986	Si:dkey-178k16.1.	Erythrocyte membrane protein band 4.1 like 4B.	0.407
LOC103467236	epb41l5	ENSPREP00000024537	ENSPREP00000023604	Si:dkey-178k16.1.	Erythrocyte membrane protein band 4.1 like 5.	0.407
LOC103469946	LOC103457606	ENSPREP00000012332	ENSPREP00000028576	Tyrosine-protein kinase.	Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.499