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LOC103478934 LOC103478934 fes fes lck lck rin1 rin1 RIN2 RIN2 LOC103466881 LOC103466881 VAV1 VAV1 LOC103462114 LOC103462114 ENSPREP00000000516 ENSPREP00000000516 plcg2 plcg2 LOC103478918 LOC103478918 SH2B2 SH2B2 pik3r3 pik3r3 ENSPREP00000004672 ENSPREP00000004672 LOC103482184 LOC103482184 tns4 tns4 chn2 chn2 tns2 tns2 bcar3 bcar3 stat1 stat1 LOC103467308 LOC103467308 LOC103465566 LOC103465566 cbl cbl vav2 vav2 socs7 socs7 nck1 nck1 LOC103470919 LOC103470919 LOC103467856 LOC103467856 ENSPREP00000030836 ENSPREP00000030836 LOC103458010 LOC103458010 LOC103476509 LOC103476509 itk itk jak1 jak1 SHE SHE pik3r1 pik3r1 inppl1 inppl1 LOC103459817 LOC103459817 blk blk ENSPREP00000027386 ENSPREP00000027386 plcg1 plcg1 abl2 abl2 LOC103472075 LOC103472075 matk matk LOC103470780 LOC103470780 SHC3 SHC3 shc1 shc1 LOC103471376 LOC103471376 LOC103478156 LOC103478156 LOC103473352 LOC103473352 LOC103465382 LOC103465382 ENSPREP00000024937 ENSPREP00000024937 ptpn11 ptpn11 inpp5d inpp5d LOC103469145 LOC103469145 ENSPREP00000023825 ENSPREP00000023825 LOC103466413 LOC103466413 LOC103479892 LOC103479892 LOC103476312 LOC103476312 grb2 grb2 LOC103477907 LOC103477907 sh2b3 sh2b3 abl1 abl1 socs6 socs6 sh2d5 sh2d5 LOC103479277 LOC103479277 grap2 grap2 LOC103463527 LOC103463527 btk btk sh2d3c sh2d3c SOCS7 SOCS7 LOC103463556 LOC103463556 LOC103463319 LOC103463319 sh2b1 sh2b1 LOC103478361 LOC103478361 shc2 shc2 socs3 socs3 sla sla LOC103478998 LOC103478998 rasa1 rasa1 dapp1 dapp1 LOC103456982 LOC103456982 LOC103467098 LOC103467098 ptpn6 ptpn6 LOC103479751 LOC103479751 SRC SRC Socs5 Socs5 LOC103458447 LOC103458447 ENSPREP00000015653 ENSPREP00000015653 VAV3 VAV3 LOC103469404 LOC103469404 stat3 stat3 supt6h supt6h pik3r2 pik3r2 LOC103471620 LOC103471620 LOC103460130 LOC103460130 TNS3-2 TNS3-2 crk crk SH2D7 SH2D7 nck2 nck2 LOC103463411 LOC103463411 jak2 jak2 LOC103460833 LOC103460833 LOC103473631 LOC103473631 LOC103481609 LOC103481609 LOC103468233 LOC103468233 jak3 jak3 LOC103469946 LOC103469946 CSK CSK ENSPREP00000011332 ENSPREP00000011332 YES1 YES1 tyk2 tyk2 LOC103458742 LOC103458742 crkl crkl ENSPREP00000009358 ENSPREP00000009358 ENSPREP00000009325 ENSPREP00000009325 ENSPREP00000009289 ENSPREP00000009289 ENSPREP00000008903 ENSPREP00000008903 ENSPREP00000008814 ENSPREP00000008814 TNS3 TNS3 LOC103461355 LOC103461355 LOC103465140 LOC103465140 hck hck fgr fgr Cish Cish SHF SHF syk syk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103478934SH2 domain-containing protein. (171 aa)
fesTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (824 aa)
lckTyrosine-protein kinase. (500 aa)
rin1Si:ch211-168d1.3. (789 aa)
RIN2Ras and Rab interactor 2. (993 aa)
LOC103466881Tensin 2a. (1689 aa)
VAV1Vav guanine nucleotide exchange factor 1. (811 aa)
LOC103462114SH2 domain containing 3A. (804 aa)
ENSPREP00000000516SOCS box domain-containing protein. (221 aa)
plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1260 aa)
LOC103478918Tyrosine-protein kinase. (509 aa)
SH2B2SH2B adaptor protein 2. (689 aa)
pik3r3Uncharacterized protein. (474 aa)
ENSPREP00000004672SH2 domain-containing protein. (141 aa)
LOC103482184Signal transducer and activator of transcription. (784 aa)
tns4SH2 domain-containing protein. (572 aa)
chn2Chimerin 2. (467 aa)
tns2Tensin 2b. (1542 aa)
bcar3BCAR3 adaptor protein, NSP family member. (743 aa)
stat1Signal transducer and activator of transcription. (714 aa)
LOC103467308Signal transducer and activator of transcription. (665 aa)
LOC103465566Si:ch211-25d12.7. (270 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (848 aa)
vav2Vav 2 guanine nucleotide exchange factor. (793 aa)
socs7Suppressor of cytokine signaling 7. (806 aa)
nck1Cytoplasmic protein. (394 aa)
LOC103470919SH2 domain containing 1A duplicate b. (157 aa)
LOC103467856Tyrosine-protein kinase. (542 aa)
ENSPREP00000030836Tensin 1b. (688 aa)
LOC103458010Tyrosine-protein kinase. (537 aa)
LOC103476509Ras and Rab interactor 2. (944 aa)
itkTyrosine-protein kinase. (617 aa)
jak1Tyrosine-protein kinase. (1174 aa)
SHESrc homology 2 domain containing E. (477 aa)
pik3r1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (727 aa)
inppl1Inositol polyphosphate phosphatase-like 1a. (1248 aa)
LOC103459817Suppressor of cytokine signaling 2. (196 aa)
blkTyrosine-protein kinase. (460 aa)
ENSPREP00000027386Suppressor of cytokine signaling 4. (395 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1271 aa)
abl2Tyrosine-protein kinase. (1187 aa)
LOC103472075Growth factor receptor-bound protein 10a. (590 aa)
matkTyrosine-protein kinase. (467 aa)
LOC103470780Uncharacterized protein. (705 aa)
SHC3SHC adaptor protein 3. (664 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (600 aa)
LOC103471376Uncharacterized protein. (383 aa)
LOC103478156Src homology 2 domain containing E. (427 aa)
LOC103473352Tensin 1. (1228 aa)
LOC103465382Signal transducer and activator of transcription. (801 aa)
ENSPREP00000024937SH2 domain-containing protein. (152 aa)
ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
inpp5dInositol polyphosphate-5-phosphatase D. (1102 aa)
LOC103469145GRB2 related adaptor protein a. (214 aa)
ENSPREP00000023825SH2 domain-containing protein. (93 aa)
LOC103466413Tyrosine-protein kinase. (449 aa)
LOC103479892Tyrosine-protein kinase. (473 aa)
LOC103476312Uncharacterized protein. (857 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
LOC103477907Cbl proto-oncogene C, E3 ubiquitin protein ligase. (550 aa)
sh2b3SH2B adaptor protein 3. (710 aa)
abl1Tyrosine-protein kinase. (1124 aa)
socs6Suppressor of cytokine signaling 6a. (459 aa)
sh2d5SH2 domain containing 5. (336 aa)
LOC103479277Signal transducing adaptor family member 2a. (360 aa)
grap2GRB2 related adaptor protein 2a. (428 aa)
LOC103463527Hematopoietic SH2 domain containing. (378 aa)
btkTyrosine-protein kinase. (637 aa)
sh2d3cSH2 domain containing 3Cb. (685 aa)
SOCS7Suppressor of cytokine signaling 7. (621 aa)
LOC103463556Src homology 2 domain containing transforming protein D, b. (422 aa)
LOC103463319Uncharacterized protein. (406 aa)
sh2b1SH2B adaptor protein 1. (861 aa)
LOC103478361Growth factor receptor-bound protein 10b. (572 aa)
shc2SHC (Src homology 2 domain containing) transforming protein 2. (715 aa)
socs3Suppressor of cytokine signaling 3. (208 aa)
slaSrc like adaptor 1a. (278 aa)
LOC103478998Uncharacterized protein. (512 aa)
rasa1RAS p21 protein activator (GTPase activating protein) 1a. (1049 aa)
dapp1Dual adaptor of phosphotyrosine and 3-phosphoinositides. (296 aa)
LOC103456982SH2 domain-containing protein. (202 aa)
LOC103467098Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
ptpn6Protein tyrosine phosphatase non-receptor type 6. (573 aa)
LOC103479751Vav 3 guanine nucleotide exchange factor b. (801 aa)
SRCTyrosine-protein kinase. (569 aa)
Socs5Suppressor of cytokine signaling 5b. (554 aa)
LOC103458447Src homology 2 domain containing transforming protein D, a. (415 aa)
ENSPREP00000015653SOCS domain-containing protein. (418 aa)
VAV3Vav guanine nucleotide exchange factor 3. (864 aa)
LOC103469404Signal transducer and activator of transcription. (787 aa)
stat3Signal transducer and activator of transcription. (825 aa)
supt6hTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1825 aa)
pik3r2Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (701 aa)
LOC103471620Inositol polyphosphate phosphatase-like 1b. (1151 aa)
LOC103460130Si:ch211-112g6.4. (367 aa)
TNS3-2Tensin 3. (1069 aa)
crkCRK proto-oncogene, adaptor protein. (315 aa)
SH2D7SH2 domain containing 7. (444 aa)
nck2Cytoplasmic protein. (393 aa)
LOC1034634111-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1309 aa)
jak2Tyrosine-protein kinase. (1190 aa)
LOC103460833Chimerin 1. (458 aa)
LOC103473631SH2 domain containing 3Ca. (708 aa)
LOC103481609Growth factor receptor bound protein 7. (525 aa)
LOC103468233Tyrosine-protein kinase. (606 aa)
jak3Tyrosine-protein kinase. (975 aa)
LOC103469946Tyrosine-protein kinase. (1122 aa)
CSKTyrosine-protein kinase. (451 aa)
ENSPREP00000011332SH2 domain-containing protein. (161 aa)
YES1Tyrosine-protein kinase. (454 aa)
tyk2Tyrosine-protein kinase. (1153 aa)
LOC103458742Tyrosine-protein kinase. (537 aa)
crklV-crk avian sarcoma virus CT10 oncogene homolog-like. (310 aa)
ENSPREP00000009358Uncharacterized protein. (158 aa)
ENSPREP00000009325GRB2 related adaptor protein b. (229 aa)
ENSPREP00000009289Signal transducing adaptor family member 2b. (337 aa)
ENSPREP00000008903SH2 domain-containing protein. (223 aa)
ENSPREP00000008814SH2 domain-containing protein. (230 aa)
TNS3Tensin 3. (1164 aa)
LOC103461355Suppressor of cytokine signaling 3a. (165 aa)
LOC103465140Cytokine inducible SH2-containing protein b. (213 aa)
hckTyrosine-protein kinase. (500 aa)
fgrTyrosine-protein kinase. (534 aa)
CishUncharacterized protein. (233 aa)
SHFSrc homology 2 domain containing F. (471 aa)
sykTyrosine-protein kinase. (614 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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