(35 nodes) PDZ domain 6 network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103481932	Si:ch211-176g6.2. (1247 aa)
	pdzd8	PDZ domain containing 8. (1204 aa)
	LOC103481054	Uncharacterized protein. (2065 aa)
	LOC103467517	Glutamate receptor interacting protein 2a. (1064 aa)
	LOC103466075	Membrane associated guanylate kinase, WW and PDZ domain containing 2b. (1538 aa)
	htra2	Si:dkey-33c12.12. (445 aa)
	ENSPREP00000023199	Glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, b. (733 aa)
	LOC103472577	Uncharacterized protein. (1105 aa)
	LOC103468230	Uncharacterized protein. (1621 aa)
	LOC103466031	SH3 and multiple ankyrin repeat domains 3a. (1984 aa)
	mast1	Microtubule associated serine/threonine kinase 1b. (1670 aa)
	pdzrn4	PDZ domain containing ring finger 4. (819 aa)
	shank1	SH3 and multiple ankyrin repeat domains 1. (834 aa)
	rims1	Regulating synaptic membrane exocytosis 1a. (1422 aa)
	frmpd2	FERM and PDZ domain containing 2. (1149 aa)
	arhgap21	Rho GTPase activating protein 21a. (1717 aa)
	LOC103464302	Glutamate receptor interacting protein 2b. (1180 aa)
	LOC103465557	Si:dkeyp-97e7.9. (414 aa)
	magi2	Membrane associated guanylate kinase, WW and PDZ domain containing 2a. (1287 aa)
	nthl1	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (452 aa)
	htra3	HtrA serine peptidase 3a. (476 aa)
	LOC103482112	Uncharacterized protein. (1421 aa)
	intu	Inturned planar cell polarity protein. (962 aa)
	LOC103479584	Rho GTPase activating protein 21b. (1781 aa)
	LOC103466916	Syndecan binding protein (syntenin) 2. (341 aa)
	grip1	Glutamate receptor interacting protein 1. (1133 aa)
	ENSPREP00000008137	PDZ domain-containing protein. (288 aa)
	rapgef2	Rap guanine nucleotide exchange factor (GEF) 2. (1615 aa)
	mast3	Microtubule associated serine/threonine kinase 3b. (1467 aa)
	LOC103469344	Rho GTPase activating protein 23a. (1802 aa)
	LOC103476093	PDZ domain containing 3b. (491 aa)
	LOC103479170	Microtubule associated serine/threonine kinase 3a. (1318 aa)
	psmd9	Proteasome 26S subunit, non-ATPase 9. (210 aa)
	MAST4	Microtubule associated serine/threonine kinase family member 4. (1751 aa)
	SYNPO2-2	Synaptopodin 2. (1507 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103464302	LOC103467517	ENSPREP00000033269	ENSPREP00000025375	Glutamate receptor interacting protein 2b.	Glutamate receptor interacting protein 2a.	0.586
LOC103464302	grip1	ENSPREP00000033269	ENSPREP00000008016	Glutamate receptor interacting protein 2b.	Glutamate receptor interacting protein 1.	0.584
LOC103467517	LOC103464302	ENSPREP00000025375	ENSPREP00000033269	Glutamate receptor interacting protein 2a.	Glutamate receptor interacting protein 2b.	0.586
LOC103467517	rapgef2	ENSPREP00000025375	ENSPREP00000011362	Glutamate receptor interacting protein 2a.	Rap guanine nucleotide exchange factor (GEF) 2.	0.465
grip1	LOC103464302	ENSPREP00000008016	ENSPREP00000033269	Glutamate receptor interacting protein 1.	Glutamate receptor interacting protein 2b.	0.584
grip1	rapgef2	ENSPREP00000008016	ENSPREP00000011362	Glutamate receptor interacting protein 1.	Rap guanine nucleotide exchange factor (GEF) 2.	0.465
intu	psmd9	ENSPREP00000004730	ENSPREP00000030720	Inturned planar cell polarity protein.	Proteasome 26S subunit, non-ATPase 9.	0.507
psmd9	intu	ENSPREP00000030720	ENSPREP00000004730	Proteasome 26S subunit, non-ATPase 9.	Inturned planar cell polarity protein.	0.507
rapgef2	LOC103467517	ENSPREP00000011362	ENSPREP00000025375	Rap guanine nucleotide exchange factor (GEF) 2.	Glutamate receptor interacting protein 2a.	0.465
rapgef2	grip1	ENSPREP00000011362	ENSPREP00000008016	Rap guanine nucleotide exchange factor (GEF) 2.	Glutamate receptor interacting protein 1.	0.465