(107 nodes) Neurotransmitter release cycle network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	unc13a	Uncharacterized protein. (1552 aa)
	LOC103462423	Amyloid beta (A4) precursor protein-binding, family A, member 2b. (770 aa)
	lin7c	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (201 aa)
	syt1	Synaptotagmin Ia. (422 aa)
	lin7a	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (225 aa)
	ppfia2	PTPRF interacting protein alpha 2. (1185 aa)
	LOC103461945	Solute carrier family 5 member 7a; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (596 aa)
	PPFIA3	PTPRF interacting protein alpha 3. (1119 aa)
	slc1a1	Amino acid transporter. (522 aa)
	LOC103465524	PRA1 family protein. (190 aa)
	ENSPREP00000031687	PRA1 family protein. (54 aa)
	LOC103472178	Regulating synaptic membrane exocytosis 3. (323 aa)
	ENSPREP00000031524	Uncharacterized protein. (156 aa)
	LOC103457187	Glutaminase a. (617 aa)
	LOC103465514	Uncharacterized protein; Belongs to the acid ceramidase family. (357 aa)
	cask	Uncharacterized protein; Belongs to the MAGUK family. (884 aa)
	maob	Amine oxidase. (566 aa)
	LOC103461905	DnaJ (Hsp40) homolog, subfamily C, member 5ab. (196 aa)
	LOC103470222	Amino acid transporter. (536 aa)
	slc1a2	Amino acid transporter. (537 aa)
	dnajc5g	DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a. (177 aa)
	chat	Choline O-acetyltransferase a; Belongs to the carnitine/choline acetyltransferase family. (676 aa)
	ENSPREP00000026258	Solute carrier family 18 member 3a. (511 aa)
	LOC103479452	Unc-13 homolog A. (1870 aa)
	SLC17A7	Solute carrier family 17 member 7. (543 aa)
	LOC103458337	J domain-containing protein. (181 aa)
	LOC103467226	Uncharacterized protein. (479 aa)
	RIMS2	Regulating synaptic membrane exocytosis 2. (1303 aa)
	SYN3	Synapsin III. (548 aa)
	LOC103464825	Glutaminase 2b (liver, mitochondrial). (514 aa)
	LOC103463013	PTPRF interacting protein alpha 1. (1183 aa)
	LOC103472577	Uncharacterized protein. (1105 aa)
	LOC103466444	Amyloid beta (A4) precursor protein-binding, family A, member 2a. (814 aa)
	Cplx2	Complexin 2. (227 aa)
	aldh5a1	Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (513 aa)
	LOC103469087	Solute carrier family 17 member 7a. (584 aa)
	LOC103467156	Amino acid transporter. (332 aa)
	LOC103464010	Amino acid transporter. (578 aa)
	SLC5A7	Solute carrier family 5 member 7; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (590 aa)
	LOC103479781	Amino acid transporter. (562 aa)
	LOC103463525	Amino acid transporter. (579 aa)
	APBA1	Uncharacterized protein. (890 aa)
	LOC103465918	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa)
	LOC103463328	RAB3A, member RAS oncogene family, b. (219 aa)
	LOC103468990	Amino acid transporter. (675 aa)
	LOC103468986	PTPRF interacting protein alpha 3. (1258 aa)
	ENSPREP00000016345	Zgc:92912. (125 aa)
	syn1	Synapsin I. (651 aa)
	LOC103458434	Amino acid transporter. (533 aa)
	ENSPREP00000014713	Aa_trans domain-containing protein. (420 aa)
	LOC103479175	RAB3A, member RAS oncogene family, b. (290 aa)
	rims1	Regulating synaptic membrane exocytosis 1a. (1422 aa)
	LOC103475771	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (722 aa)
	LOC103475843	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family. (950 aa)
	SLC6A13	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (638 aa)
	LOC103474139	Si:ch211-105f12.2. (209 aa)
	slc32a1	Solute carrier family 32 member 1. (526 aa)
	LOC103467585	Synapsin IIa. (467 aa)
	LOC103467587	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (710 aa)
	ENSPREP00000011853	Uncharacterized protein. (755 aa)
	LOC103461623	Amino acid transporter. (110 aa)
	abat	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
	LOC103474103	Amino acid transporter. (386 aa)
	LOC103473595	Uncharacterized protein. (1306 aa)
	praf2	PRA1 family protein. (209 aa)
	slc6a11	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (668 aa)
	slc6a1	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (605 aa)
	LOC103474076	Amyloid beta (A4) precursor protein-binding, family A, member 1b. (1189 aa)
	syn2	Uncharacterized protein. (789 aa)
	gls2	Glutaminase 2a (liver, mitochondrial). (600 aa)
	LOC103466656	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (560 aa)
	CPLX1	Complexin 1. (133 aa)
	LOC103474794	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (583 aa)
	ENSPREP00000008454	C2 domain-containing protein. (216 aa)
	UNC13C	Unc-13 homolog C. (2664 aa)
	Unc13b	Uncharacterized protein. (3189 aa)
	lin7b	L27 domain-containing protein. (226 aa)
	LOC103458696	Amino acid transporter. (490 aa)
	LOC103479193	Amino acid transporter. (554 aa)
	arl6ip5	PRA1 family protein. (190 aa)
	ENSPREP00000006420	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (168 aa)
	ENSPREP00000006413	Uncharacterized protein. (187 aa)
	gad1	Glutamate decarboxylase 1a. (558 aa)
	ENSPREP00000005821	C2 domain-containing protein. (318 aa)
	ENSPREP00000005740	PDZ domain-containing protein. (394 aa)
	ppfia4	PTPRF interacting protein alpha 4. (1135 aa)
	LOC103462732	Amino acid transporter. (559 aa)
	LOC103463214	Amino acid transporter. (626 aa)
	LOC103464574	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (637 aa)
	LOC103464575	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (623 aa)
	LOC103469794	Uncharacterized protein. (1517 aa)
	LOC103467735	DnaJ (Hsp40) homolog, subfamily C, member 5aa. (199 aa)
	LOC103463779	Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (560 aa)
	LOC103478943	Glutamate decarboxylase 1b. (583 aa)
	rimbp2	RIMS binding protein 2. (1514 aa)
	LOC103464597	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (608 aa)
	ENSPREP00000002501	Vesicle-associated membrane protein 2. (122 aa)
	LOC103464598	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (627 aa)
	LOC103468036	Aa_trans domain-containing protein. (512 aa)
	dnajc5b	DnaJ heat shock protein family (Hsp40) member C5 beta. (197 aa)
	ENSPREP00000001718	Uncharacterized protein. (156 aa)
	LOC103461842	EF-hand_14 domain-containing protein. (563 aa)
	LOC103481437	Solute carrier family 18 member A3. (518 aa)
	LOC103481435	Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family. (633 aa)
	LOC103472839	Vesicle-associated membrane protein 1. (150 aa)
	gad2	Glutamate decarboxylase 2. (585 aa)
	ENSPREP00000000351	Complexin 2, like. (134 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APBA1	LOC103472178	ENSPREP00000018336	ENSPREP00000031671	Uncharacterized protein.	Regulating synaptic membrane exocytosis 3.	0.499
APBA1	LOC103472577	ENSPREP00000018336	ENSPREP00000023069	Uncharacterized protein.	Uncharacterized protein.	0.695
APBA1	LOC103475843	ENSPREP00000018336	ENSPREP00000013706	Uncharacterized protein.	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	0.953
APBA1	RIMS2	ENSPREP00000018336	ENSPREP00000023895	Uncharacterized protein.	Regulating synaptic membrane exocytosis 2.	0.695
APBA1	cask	ENSPREP00000018336	ENSPREP00000030734	Uncharacterized protein.	Uncharacterized protein; Belongs to the MAGUK family.	0.953
APBA1	lin7a	ENSPREP00000018336	ENSPREP00000033127	Uncharacterized protein.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.581
APBA1	lin7b	ENSPREP00000018336	ENSPREP00000007929	Uncharacterized protein.	L27 domain-containing protein.	0.581
APBA1	lin7c	ENSPREP00000018336	ENSPREP00000033453	Uncharacterized protein.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.581
APBA1	rims1	ENSPREP00000018336	ENSPREP00000014499	Uncharacterized protein.	Regulating synaptic membrane exocytosis 1a.	0.428
Cplx2	ENSPREP00000002501	ENSPREP00000022098	ENSPREP00000002501	Complexin 2.	Vesicle-associated membrane protein 2.	0.435
Cplx2	ENSPREP00000005740	ENSPREP00000022098	ENSPREP00000005740	Complexin 2.	PDZ domain-containing protein.	0.473
Cplx2	ENSPREP00000005821	ENSPREP00000022098	ENSPREP00000005821	Complexin 2.	C2 domain-containing protein.	0.473
Cplx2	ENSPREP00000008454	ENSPREP00000022098	ENSPREP00000008454	Complexin 2.	C2 domain-containing protein.	0.507
Cplx2	ENSPREP00000014713	ENSPREP00000022098	ENSPREP00000014713	Complexin 2.	Aa_trans domain-containing protein.	0.458
Cplx2	ENSPREP00000016345	ENSPREP00000022098	ENSPREP00000016345	Complexin 2.	Zgc:92912.	0.435
Cplx2	LOC103458337	ENSPREP00000022098	ENSPREP00000025278	Complexin 2.	J domain-containing protein.	0.442
Cplx2	LOC103461905	ENSPREP00000022098	ENSPREP00000029776	Complexin 2.	DnaJ (Hsp40) homolog, subfamily C, member 5ab.	0.442
Cplx2	LOC103463328	ENSPREP00000022098	ENSPREP00000016866	Complexin 2.	RAB3A, member RAS oncogene family, b.	0.474
Cplx2	LOC103467585	ENSPREP00000022098	ENSPREP00000012015	Complexin 2.	Synapsin IIa.	0.461
Cplx2	LOC103467735	ENSPREP00000022098	ENSPREP00000003061	Complexin 2.	DnaJ (Hsp40) homolog, subfamily C, member 5aa.	0.442