35 items (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ercc2	Excision repair cross-complementation group 2. (655 aa)
	polr2l	Polymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
	polr2d	Polymerase (RNA) II (DNA directed) polypeptide D. (104 aa)
	ncbp2	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (194 aa)
	ercc3	Excision repair cross-complementation group 3. (783 aa)
	gtf2f2	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (312 aa)
	gtf2h3	General transcription factor IIH, polypeptide 3. (277 aa)
	LOC103478624	Si:dkey-12j5.1. (361 aa)
	gtf2h4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (434 aa)
	nelfe	Negative elongation factor complex member E. (325 aa)
	polr2f	Polymerase (RNA) II (DNA directed) polypeptide F. (98 aa)
	polr2g	Polymerase (RNA) II (DNA directed) polypeptide G-like. (172 aa)
	Ctdp1	FCP1 homology domain-containing protein. (271 aa)
	mnat1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
	polr2j	Polymerase (RNA) II (DNA directed) polypeptide J. (117 aa)
	LOC103461004	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (267 aa)
	gtf2h1	General transcription factor IIH, polypeptide 1. (550 aa)
	nelfb	Negative elongation factor complex member B. (587 aa)
	nelfcd	Negative elongation factor complex member C/D. (578 aa)
	polr2a	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1966 aa)
	LOC103470674	General transcription factor IIH subunit. (420 aa)
	polr2b	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
	ENSPREP00000012814	Uncharacterized protein. (74 aa)
	supt4h1	SPT4 homolog, DSIF elongation factor subunit. (174 aa)
	polr2h	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	supt5h	Transcription elongation factor SPT5. (1059 aa)
	POLR2E	RNA polymerase II subunit E. (210 aa)
	NCBP1	Nuclear cap binding protein subunit 1. (797 aa)
	gtf2h5	General transcription factor IIH, polypeptide 5. (71 aa)
	ccnh	Cyclin H; Belongs to the cyclin family. (319 aa)
	polr2i	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
	nelfa	Negative elongation factor complex member A. (547 aa)
	polr2c	Polymerase (RNA) II (DNA directed) polypeptide C. (273 aa)
	cdk7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (387 aa)
	ENSPREP00000001027	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (467 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ctdp1	ENSPREP00000001027	ENSPREP00000024377	ENSPREP00000001027	FCP1 homology domain-containing protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.996
Ctdp1	ENSPREP00000012814	ENSPREP00000024377	ENSPREP00000012814	FCP1 homology domain-containing protein.	Uncharacterized protein.	0.806
Ctdp1	LOC103461004	ENSPREP00000024377	ENSPREP00000020577	FCP1 homology domain-containing protein.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.909
Ctdp1	NCBP1	ENSPREP00000024377	ENSPREP00000008871	FCP1 homology domain-containing protein.	Nuclear cap binding protein subunit 1.	0.695
Ctdp1	POLR2E	ENSPREP00000024377	ENSPREP00000009571	FCP1 homology domain-containing protein.	RNA polymerase II subunit E.	0.876
Ctdp1	ccnh	ENSPREP00000024377	ENSPREP00000006353	FCP1 homology domain-containing protein.	Cyclin H; Belongs to the cyclin family.	0.732
Ctdp1	cdk7	ENSPREP00000024377	ENSPREP00000003727	FCP1 homology domain-containing protein.	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily.	0.759
Ctdp1	gtf2f2	ENSPREP00000024377	ENSPREP00000030834	FCP1 homology domain-containing protein.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.909
Ctdp1	gtf2h4	ENSPREP00000024377	ENSPREP00000029112	FCP1 homology domain-containing protein.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.665
Ctdp1	gtf2h5	ENSPREP00000024377	ENSPREP00000006463	FCP1 homology domain-containing protein.	General transcription factor IIH, polypeptide 5.	0.630
Ctdp1	mnat1	ENSPREP00000024377	ENSPREP00000022935	FCP1 homology domain-containing protein.	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.	0.740
Ctdp1	ncbp2	ENSPREP00000024377	ENSPREP00000031952	FCP1 homology domain-containing protein.	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	0.732
Ctdp1	nelfe	ENSPREP00000024377	ENSPREP00000003241	FCP1 homology domain-containing protein.	Negative elongation factor complex member E.	0.696
Ctdp1	polr2a	ENSPREP00000024377	ENSPREP00000019508	FCP1 homology domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.986
Ctdp1	polr2b	ENSPREP00000024377	ENSPREP00000016486	FCP1 homology domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.965
Ctdp1	polr2c	ENSPREP00000024377	ENSPREP00000004397	FCP1 homology domain-containing protein.	Polymerase (RNA) II (DNA directed) polypeptide C.	0.980
Ctdp1	polr2d	ENSPREP00000024377	ENSPREP00000032271	FCP1 homology domain-containing protein.	Polymerase (RNA) II (DNA directed) polypeptide D.	0.944
Ctdp1	polr2f	ENSPREP00000024377	ENSPREP00000024818	FCP1 homology domain-containing protein.	Polymerase (RNA) II (DNA directed) polypeptide F.	0.881
Ctdp1	polr2g	ENSPREP00000024377	ENSPREP00000024621	FCP1 homology domain-containing protein.	Polymerase (RNA) II (DNA directed) polypeptide G-like.	0.981
Ctdp1	polr2h	ENSPREP00000024377	ENSPREP00000010630	FCP1 homology domain-containing protein.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.798