STRINGSTRING
adcy6 adcy6 ENSPREP00000000270 ENSPREP00000000270 Cacna1a Cacna1a adra2a adra2a prkaca prkaca LOC103462833 LOC103462833 LOC103465545 LOC103465545 LOC103464341 LOC103464341 CACNA1D CACNA1D TKT TKT LOC103468620 LOC103468620 LOC103469304 LOC103469304 LOC103456937 LOC103456937 LOC103456785 LOC103456785 LOC103464608 LOC103464608 acaca acaca LOC103472833 LOC103472833 ENSPREP00000002125 ENSPREP00000002125 LOC103459225 LOC103459225 LOC103478552 LOC103478552 LOC103467718 LOC103467718 LOC103472243 LOC103472243 LOC103473462 LOC103473462 LOC103473463 LOC103473463 LOC103473464 LOC103473464 LOC103473465 LOC103473465 adcy5 adcy5 gng10 gng10 kcnb1 kcnb1 ENSPREP00000005233 ENSPREP00000005233 LOC103464538 LOC103464538 fasn fasn prkar2b prkar2b LOC103459268 LOC103459268 LOC103468785 LOC103468785 LOC103476610 LOC103476610 LOC103464516 LOC103464516 cacna2d2 cacna2d2 taldo1 taldo1 ENSPREP00000006813 ENSPREP00000006813 LOC103459286 LOC103459286 LOC103458407 LOC103458407 Itpr3 Itpr3 ENSPREP00000007384 ENSPREP00000007384 LOC103462170 LOC103462170 slc25a20 slc25a20 kcns3 kcns3 prkar1b prkar1b LOC103468179 LOC103468179 LOC103465120 LOC103465120 gcg gcg LOC103465119 LOC103465119 GNG4 GNG4 LOC103476073 LOC103476073 gng12 gng12 cacnb2 cacnb2 LOC103465210 LOC103465210 mlx mlx LOC103479663 LOC103479663 LOC103465228 LOC103465228 LOC103481657 LOC103481657 ENSPREP00000015124 ENSPREP00000015124 acsl3 acsl3 gnb1 gnb1 LOC103458452 LOC103458452 gng7 gng7 LOC103476744 LOC103476744 gng3 gng3 rapgefl1 rapgefl1 LOC103463549 LOC103463549 LOC103463548 LOC103463548 LOC103460216 LOC103460216 gnb3 gnb3 prkar2a prkar2a slc2a2 slc2a2 LOC103468320 LOC103468320 LOC103464733 LOC103464733 LOC103479350 LOC103479350 LOC103463990 LOC103463990 LOC103479890 LOC103479890 ADRA2C ADRA2C adipor1 adipor1 cacna2d1 cacna2d1 LOC103461074 LOC103461074 prkacb prkacb GNG5 GNG5 gnb5 gnb5 GNB4 GNB4 ENSPREP00000022514 ENSPREP00000022514 LOC103465353 LOC103465353 PRKAB2 PRKAB2 snx19 snx19 PLCB1 PLCB1 Plcb1 Plcb1 Kcng2 Kcng2 LOC103479395 LOC103479395 LOC103466076 LOC103466076 gng2 gng2 LOC103462964 LOC103462964 LOC103464081 LOC103464081 itpr2 itpr2 LOC103467440 LOC103467440 prkar1a prkar1a LOC103470235 LOC103470235 LOC103470237 LOC103470237 plcb3 plcb3 kcnj11 kcnj11 abcc8 abcc8 LOC103470977 LOC103470977 marcks marcks mlxip mlxip prkaa2 prkaa2 LOC103465516 LOC103465516 cacna1s cacna1s PLCB2 PLCB2 LOC103467316 LOC103467316 LOC103459297 LOC103459297 LOC103459298 LOC103459298 LOC103467797 LOC103467797 LOC103475780 LOC103475780 acacb acacb LOC103475800 LOC103475800 LOC103462484 LOC103462484
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
adcy6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1172 aa)
ENSPREP00000000270Ca_chan_IQ domain-containing protein. (282 aa)
Cacna1aUncharacterized protein. (426 aa)
adra2aAdrenoceptor alpha 2A. (421 aa)
prkacaUncharacterized protein; Belongs to the protein kinase superfamily. (327 aa)
LOC103462833Guanine nucleotide binding protein (G protein), gamma 13a. (67 aa)
LOC103465545Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
LOC103464341Adrenoceptor alpha 2C. (476 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2236 aa)
TKTTransketolase. (629 aa)
LOC103468620Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a. (2209 aa)
LOC103469304Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
LOC103456937Carrier domain-containing protein. (2076 aa)
LOC103456785Si:dkey-61p9.11. (2009 aa)
LOC103464608Calcium channel, voltage-dependent, alpha 2/delta subunit 2b. (1102 aa)
acacaAcetyl-CoA carboxylase alpha. (2251 aa)
LOC103472833Guanine nucleotide binding protein (G protein), beta polypeptide 3b. (342 aa)
ENSPREP00000002125ZP domain-containing protein. (372 aa)
LOC103459225Calcium channel, voltage-dependent, alpha 2/delta subunit 1a. (983 aa)
LOC103478552Uncharacterized protein. (505 aa)
LOC103467718Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2073 aa)
LOC103472243Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
LOC103473462Uncharacterized protein. (297 aa)
LOC103473463G protein subunit alpha 14. (352 aa)
LOC103473464Guanine nucleotide binding protein (G protein), alpha 14. (351 aa)
LOC103473465G protein subunit alpha q. (359 aa)
adcy5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1213 aa)
gng10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
kcnb1Potassium voltage-gated channel, Shab-related subfamily, member 1; Belongs to the potassium channel family. (836 aa)
ENSPREP00000005233Rap guanine nucleotide exchange factor (GEF) 5a. (540 aa)
LOC103464538Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b. (355 aa)
fasnCoiled-coil domain containing 57. (2516 aa)
prkar2bProtein kinase cAMP-dependent type II regulatory subunit beta. (384 aa)
LOC103459268Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1730 aa)
LOC103468785Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (351 aa)
LOC1034766101-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1127 aa)
LOC103464516Guanine nucleotide binding protein (G protein), beta polypeptide 1b. (340 aa)
cacna2d2Calcium channel, voltage-dependent, alpha 2/delta subunit 2a. (1112 aa)
taldo1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (339 aa)
ENSPREP00000006813Potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3a; Belongs to the potassium channel family. (484 aa)
LOC103459286Adiponectin receptor 2. (343 aa)
LOC103458407Rap guanine nucleotide exchange factor (GEF) 4. (917 aa)
Itpr3MIR domain-containing protein. (185 aa)
ENSPREP00000007384Ion_trans domain-containing protein. (477 aa)
LOC103462170Guanine nucleotide binding protein (G protein), beta 5b. (345 aa)
slc25a20Protein kinase, cAMP-dependent, regulatory, type II, alpha, B. (400 aa)
kcns3Potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3b; Belongs to the potassium channel family. (498 aa)
prkar1bProtein kinase, cAMP-dependent, regulatory, type I, beta. (511 aa)
LOC103468179Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC103465120Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2102 aa)
gcgGlucagon b. (115 aa)
LOC103465119Transketolase a. (652 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC103476073BHLH domain-containing protein. (850 aa)
gng12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (96 aa)
cacnb2Calcium channel, voltage-dependent, beta 2a. (668 aa)
LOC103465210Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (798 aa)
mlxMAX dimerization protein MLX. (267 aa)
LOC103479663Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. (351 aa)
LOC103465228Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a. (355 aa)
LOC103481657Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
ENSPREP00000015124THAP-type domain-containing protein. (104 aa)
acsl3Uncharacterized protein. (719 aa)
gnb1Guanine nucleotide binding protein (G protein), beta polypeptide 1a. (340 aa)
LOC103458452Guanine nucleotide binding protein (G protein), alpha 11b (Gq class). (354 aa)
gng7Guanine nucleotide binding protein (G protein), gamma 7. (78 aa)
LOC103476744THAP-type domain-containing protein. (197 aa)
gng3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
rapgefl1Rap guanine nucleotide exchange factor (GEF)-like 1. (381 aa)
LOC103463549Guanine nucleotide binding protein (G protein), alpha 11a (Gq class). (359 aa)
LOC103463548Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4. (368 aa)
LOC103460216Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1776 aa)
gnb3Guanine nucleotide binding protein (G protein), beta polypeptide 3a. (296 aa)
prkar2aProtein kinase, cAMP-dependent, regulatory, type II, alpha A. (388 aa)
slc2a2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (503 aa)
LOC103468320Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
LOC103464733Solute carrier family 2 member 1b; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (493 aa)
LOC103479350Zgc:171558. (952 aa)
LOC103463990Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC103479890Calcium channel, voltage-dependent, beta 2b. (604 aa)
ADRA2CAdrenoceptor alpha 2C. (425 aa)
adipor1Adiponectin receptor 1a. (380 aa)
cacna2d1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1069 aa)
LOC103461074Uncharacterized protein; Belongs to the CD36 family. (95 aa)
prkacbUncharacterized protein; Belongs to the protein kinase superfamily. (380 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
gnb5Guanine nucleotide binding protein (G protein), beta 5a. (380 aa)
GNB4G protein subunit beta 4. (340 aa)
ENSPREP00000022514ZP domain-containing protein. (320 aa)
LOC103465353Inositol 1,4,5-trisphosphate receptor, type 1a. (2685 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (267 aa)
snx19Sorting nexin 19b. (977 aa)
PLCB1Phosphoinositide phospholipase C. (1031 aa)
Plcb1Uncharacterized protein. (33 aa)
Kcng2Potassium voltage-gated channel, subfamily G, member 2; Belongs to the potassium channel family. (526 aa)
LOC103479395Acyl-CoA synthetase long chain family member 3b. (709 aa)
LOC103466076Uncharacterized protein. (354 aa)
gng2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
LOC103462964THAP-type domain-containing protein. (198 aa)
LOC103464081Calcium channel, voltage-dependent, R type, alpha 1E subunit a. (2524 aa)
itpr2Inositol 1,4,5-trisphosphate receptor, type 2. (2699 aa)
LOC103467440Transketolase b. (626 aa)
prkar1aProtein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b. (380 aa)
LOC103470235Uncharacterized protein. (359 aa)
LOC103470237Guanine nucleotide binding protein (G protein), alpha 14a. (354 aa)
plcb31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1208 aa)
kcnj11Potassium inwardly-rectifying channel, subfamily J, member 11. (372 aa)
abcc8ATP-binding cassette, sub-family C (CFTR/MRP), member 8. (1599 aa)
LOC103470977Acyl-CoA synthetase long chain family member 4a. (567 aa)
marcksMyristoylated alanine-rich protein kinase C substrate a. (261 aa)
mlxipMLX interacting protein. (805 aa)
prkaa2Non-specific serine/threonine protein kinase. (557 aa)
LOC103465516Inositol 1,4,5-trisphosphate receptor, type 1b. (2726 aa)
cacna1sVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1788 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1272 aa)
LOC103467316Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1179 aa)
LOC103459297Uncharacterized protein. (285 aa)
LOC103459298CD36 molecule (thrombospondin receptor); Belongs to the CD36 family. (409 aa)
LOC103467797Rap guanine nucleotide exchange factor (GEF) 3. (878 aa)
LOC103475780WD_REPEATS_REGION domain-containing protein. (223 aa)
acacbAcetyl-CoA carboxylase beta. (2054 aa)
LOC103475800Sorting nexin 19a. (998 aa)
LOC103462484ZP domain-containing protein. (415 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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