(11 nodes) YAP1- and WWTR1 (TAZ)-stimulated gene expression network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tead3	TEA domain family member 3 b. (323 aa)
	kat2b	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (798 aa)
	LOC103466248	TEA domain family member 1a. (428 aa)
	LOC103470367	Uncharacterized protein. (539 aa)
	TEAD1	TEA domain family member 1b. (389 aa)
	LOC103467419	TEA domain transcription factor 3. (405 aa)
	nkx2-5	NK2 homeobox 5. (316 aa)
	TEAD4	TEA domain transcription factor 4. (423 aa)
	tbx4	T-box transcription factor 4. (549 aa)
	yap1	Yes-associated protein 1. (433 aa)
	LOC103473796	T-box transcription factor 5a. (524 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103466248	yap1	ENSPREP00000002228	ENSPREP00000022087	TEA domain family member 1a.	Yes-associated protein 1.	0.907
LOC103467419	yap1	ENSPREP00000029322	ENSPREP00000022087	TEA domain transcription factor 3.	Yes-associated protein 1.	0.907
LOC103470367	nkx2-5	ENSPREP00000001976	ENSPREP00000028859	Uncharacterized protein.	NK2 homeobox 5.	0.813
LOC103470367	yap1	ENSPREP00000001976	ENSPREP00000022087	Uncharacterized protein.	Yes-associated protein 1.	0.709
LOC103473796	nkx2-5	ENSPREP00000021410	ENSPREP00000028859	T-box transcription factor 5a.	NK2 homeobox 5.	0.862
LOC103473796	yap1	ENSPREP00000021410	ENSPREP00000022087	T-box transcription factor 5a.	Yes-associated protein 1.	0.731
TEAD1	yap1	ENSPREP00000034158	ENSPREP00000022087	TEA domain family member 1b.	Yes-associated protein 1.	0.907
TEAD4	yap1	ENSPREP00000028498	ENSPREP00000022087	TEA domain transcription factor 4.	Yes-associated protein 1.	0.907
kat2b	yap1	ENSPREP00000009570	ENSPREP00000022087	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	Yes-associated protein 1.	0.650
nkx2-5	LOC103470367	ENSPREP00000028859	ENSPREP00000001976	NK2 homeobox 5.	Uncharacterized protein.	0.813
nkx2-5	LOC103473796	ENSPREP00000028859	ENSPREP00000021410	NK2 homeobox 5.	T-box transcription factor 5a.	0.862
nkx2-5	tbx4	ENSPREP00000028859	ENSPREP00000022695	NK2 homeobox 5.	T-box transcription factor 4.	0.757
tbx4	nkx2-5	ENSPREP00000022695	ENSPREP00000028859	T-box transcription factor 4.	NK2 homeobox 5.	0.757
tbx4	yap1	ENSPREP00000022695	ENSPREP00000022087	T-box transcription factor 4.	Yes-associated protein 1.	0.709
tead3	yap1	ENSPREP00000017994	ENSPREP00000022087	TEA domain family member 3 b.	Yes-associated protein 1.	0.907
yap1	LOC103466248	ENSPREP00000022087	ENSPREP00000002228	Yes-associated protein 1.	TEA domain family member 1a.	0.907
yap1	LOC103467419	ENSPREP00000022087	ENSPREP00000029322	Yes-associated protein 1.	TEA domain transcription factor 3.	0.907
yap1	LOC103470367	ENSPREP00000022087	ENSPREP00000001976	Yes-associated protein 1.	Uncharacterized protein.	0.709
yap1	LOC103473796	ENSPREP00000022087	ENSPREP00000021410	Yes-associated protein 1.	T-box transcription factor 5a.	0.731
yap1	TEAD1	ENSPREP00000022087	ENSPREP00000034158	Yes-associated protein 1.	TEA domain family member 1b.	0.907