STRINGSTRING
LOC103478167 LOC103478167 wasl wasl LOC103477991 LOC103477991 LOC108165628 LOC108165628 LOC103477993 LOC103477993 LOC103479751 LOC103479751 LOC103458433 LOC103458433 SRC SRC cltcl1 cltcl1 epha4 epha4 ACTR3C ACTR3C ENSPREP00000015841 ENSPREP00000015841 LOC103457340 LOC103457340 ENSPREP00000015409 ENSPREP00000015409 ENSPREP00000015400 ENSPREP00000015400 VAV3 VAV3 epha2 epha2 ephb6 ephb6 ENSPREP00000013905 ENSPREP00000013905 LOC103468246 LOC103468246 cltc cltc LOC103460840 LOC103460840 ENSPREP00000013033 ENSPREP00000013033 LOC103458271 LOC103458271 Cfl1 Cfl1 ENSPREP00000012617 ENSPREP00000012617 ENSPREP00000012596 ENSPREP00000012596 LOC103479804 LOC103479804 YES1 YES1 EFNA2 EFNA2 ephb3 ephb3 arpc3 arpc3 LOC103458742 LOC103458742 rock1 rock1 Dstn Dstn LOC103468143 LOC103468143 mmp2 mmp2 LOC103479062 LOC103479062 LOC103474014 LOC103474014 LOC103468132 LOC103468132 LOC103471122 LOC103471122 ENSPREP00000008107 ENSPREP00000008107 ENSPREP00000008026 ENSPREP00000008026 ENSPREP00000008014 ENSPREP00000008014 epha5 epha5 rock2 rock2 ENSPREP00000007450 ENSPREP00000007450 psen2 psen2 LOC103474020 LOC103474020 LOC103466916 LOC103466916 rasa1 rasa1 LOC103464524 LOC103464524 CDC42 CDC42 LOC103474743 LOC103474743 Cfl2 Cfl2 ENSPREP00000005261 ENSPREP00000005261 ENSPREP00000005246 ENSPREP00000005246 psenen psenen LOC103475930 LOC103475930 was was LOC103460558 LOC103460558 fmn2 fmn2 LOC103468061 LOC103468061 epha7 epha7 LOC103472837 LOC103472837 NCSTN NCSTN actr2 actr2 clta clta VAV1 VAV1 LOC103462148 LOC103462148 LOC103462249 LOC103462249 LOC103462254 LOC103462254 LOC103467158 LOC103467158 EPHA6 EPHA6 LOC103458404 LOC103458404 LOC103479267 LOC103479267 epha3 epha3 LOC103468798 LOC103468798 TIAM1 TIAM1 LOC103479263 LOC103479263 LOC103479201 LOC103479201 arpc2 arpc2 fndc3b fndc3b LOC103462758 LOC103462758 LOC103465240 LOC103465240 LOC103474994 LOC103474994 LOC103465991 LOC103465991 ap2m1 ap2m1 ephb2 ephb2 LOC103467157 LOC103467157 ENSPREP00000021359 ENSPREP00000021359 fndc3a fndc3a LOC103480564 LOC103480564 LOC103479892 LOC103479892 dnm1 dnm1 Kalrn Kalrn ENSPREP00000023726 ENSPREP00000023726 EFNA5 EFNA5 ACTR3 ACTR3 ENSPREP00000024187 ENSPREP00000024187 grin2b grin2b ARPC4 ARPC4 LOC103470792 LOC103470792 LOC103470791 LOC103470791 ENSPREP00000025259 ENSPREP00000025259 ephb1 ephb1 ENSPREP00000025471 ENSPREP00000025471 Ephb1 Ephb1 LOC103478166 LOC103478166 pak1 pak1 LOC103476383 LOC103476383 LOC103465423 LOC103465423 actb actb aph1a aph1a efnb2 efnb2 epha8 epha8 hras hras LOC103472698 LOC103472698 LOC103472699 LOC103472699 FMN1 FMN1 LOC103458010 LOC103458010 pak2 pak2 LOC103467856 LOC103467856 efnb1 efnb1 LOC103463084 LOC103463084 LOC103473962 LOC103473962 ENSPREP00000032273 ENSPREP00000032273 LOC103461943 LOC103461943 vav2 vav2 MMP9 MMP9 ap2s1 ap2s1 PAK3 PAK3 ephb4 ephb4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103478167Ephrin-A1b; Belongs to the ephrin family. (232 aa)
waslWASP like actin nucleation promoting factor b. (425 aa)
LOC103477991Uncharacterized protein. (191 aa)
LOC108165628Rho guanine nucleotide exchange factor (GEF) 7b. (621 aa)
LOC103477993Uncharacterized protein. (134 aa)
LOC103479751Vav 3 guanine nucleotide exchange factor b. (801 aa)
LOC103458433Non-specific serine/threonine protein kinase. (507 aa)
SRCTyrosine-protein kinase. (569 aa)
cltcl1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1696 aa)
epha4Eph receptor A4, like. (979 aa)
ACTR3CActin related protein 3C; Belongs to the actin family. (418 aa)
ENSPREP00000015841FH2 domain-containing protein. (221 aa)
LOC103457340Formin 1. (1137 aa)
ENSPREP00000015409TyrKc domain-containing protein. (316 aa)
ENSPREP00000015400Eph LBD domain-containing protein. (324 aa)
VAV3Vav guanine nucleotide exchange factor 3. (864 aa)
epha2Eph receptor A2 b. (992 aa)
ephb6Receptor protein-tyrosine kinase. (988 aa)
ENSPREP00000013905Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (186 aa)
LOC103468246Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (150 aa)
cltcClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1700 aa)
LOC103460840Uncharacterized protein; Belongs to the actin family. (387 aa)
ENSPREP00000013033Uncharacterized protein. (170 aa)
LOC103458271Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (388 aa)
Cfl1Cofilin 1; Belongs to the actin-binding proteins ADF family. (180 aa)
ENSPREP00000012617EphA2_TM domain-containing protein. (188 aa)
ENSPREP00000012596Eph LBD domain-containing protein. (221 aa)
LOC103479804Rho guanine nucleotide exchange factor (GEF) 7a. (757 aa)
YES1Tyrosine-protein kinase. (454 aa)
EFNA2Ephrin RBD domain-containing protein; Belongs to the ephrin family. (169 aa)
ephb3Receptor protein-tyrosine kinase. (1013 aa)
arpc3Actin related protein 2/3 complex, subunit 3. (203 aa)
LOC103458742Tyrosine-protein kinase. (537 aa)
rock1Rho-associated, coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1263 aa)
DstnADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (171 aa)
LOC103468143AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (938 aa)
mmp2Matrix metallopeptidase 2. (657 aa)
LOC103479062Eph receptor B3a. (959 aa)
LOC103474014Ephrin-A5a; Belongs to the ephrin family. (229 aa)
LOC103468132Zgc:86896. (356 aa)
LOC103471122Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (200 aa)
ENSPREP00000008107Intersectin 1 (SH3 domain protein). (1107 aa)
ENSPREP00000008026Uncharacterized protein. (143 aa)
ENSPREP00000008014Uncharacterized protein; Belongs to the actin family. (180 aa)
epha5Uncharacterized protein. (1013 aa)
rock2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1401 aa)
ENSPREP00000007450Uncharacterized protein. (511 aa)
psen2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (430 aa)
LOC103474020Uncharacterized protein; Belongs to the actin family. (382 aa)
LOC103466916Syndecan binding protein (syntenin) 2. (341 aa)
rasa1RAS p21 protein activator (GTPase activating protein) 1a. (1049 aa)
LOC103464524Eph receptor A2 a. (975 aa)
CDC42Cell division cycle 42. (191 aa)
LOC103474743Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1685 aa)
Cfl2Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family. (187 aa)
ENSPREP00000005261Si:ch211-1o7.3. (382 aa)
ENSPREP00000005246Protein kinase domain-containing protein. (250 aa)
psenenUncharacterized protein. (66 aa)
LOC103475930Zgc:101810; Belongs to the actin family. (394 aa)
wasWASP actin nucleation promoting factor a. (529 aa)
LOC103460558Uncharacterized protein. (980 aa)
fmn2FH2 domain-containing protein. (1320 aa)
LOC103468061Eph receptor B2a. (963 aa)
epha7Eph receptor A7. (1078 aa)
LOC103472837Uncharacterized protein. (196 aa)
NCSTNNicastrin. (699 aa)
actr2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
cltaClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (220 aa)
VAV1Vav guanine nucleotide exchange factor 1. (811 aa)
LOC103462148Uncharacterized protein. (375 aa)
LOC103462249Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (365 aa)
LOC103462254Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (380 aa)
LOC103467158Uncharacterized protein. (664 aa)
EPHA6EPH receptor A6. (1000 aa)
LOC103458404Ephrin-A2a; Belongs to the ephrin family. (208 aa)
LOC103479267Uncharacterized protein. (1084 aa)
epha3Eph receptor A3. (899 aa)
LOC103468798Glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b. (1596 aa)
TIAM1T cell lymphoma invasion and metastasis 1a. (1672 aa)
LOC103479263Eph receptor A4b. (949 aa)
LOC103479201Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (150 aa)
arpc2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (188 aa)
fndc3bFibronectin type III domain containing 3Ba. (1175 aa)
LOC103462758Uncharacterized protein. (583 aa)
LOC103465240Actin related protein 2/3 complex, subunit 4. (231 aa)
LOC103474994T cell lymphoma invasion and metastasis 1b. (1596 aa)
LOC103465991WASP like actin nucleation promoting factor a. (525 aa)
ap2m1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (358 aa)
ephb2Eph receptor B2b. (1059 aa)
LOC103467157Matrix metallopeptidase 9. (670 aa)
ENSPREP00000021359Matrix metallopeptidase 9. (634 aa)
fndc3aFibronectin type III domain containing 3A. (1236 aa)
LOC103480564Ephrin-B3a; Belongs to the ephrin family. (338 aa)
LOC103479892Tyrosine-protein kinase. (473 aa)
dnm1Dynamin 1a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
KalrnKalirin RhoGEF kinase a. (1623 aa)
ENSPREP00000023726Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (399 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (224 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (418 aa)
ENSPREP00000024187CARD domain-containing protein. (95 aa)
grin2bUncharacterized protein. (1706 aa)
ARPC4Actin related protein 2/3 complex subunit 4. (195 aa)
LOC103470792Uncharacterized protein. (400 aa)
LOC103470791Uncharacterized protein. (372 aa)
ENSPREP00000025259Uncharacterized protein; Belongs to the actin family. (240 aa)
ephb1EPH receptor B1. (701 aa)
ENSPREP00000025471Si:dkey-246i14.3; Belongs to the ephrin family. (167 aa)
Ephb1Eph LBD domain-containing protein. (332 aa)
LOC103478166Ephrin-A3b; Belongs to the ephrin family. (221 aa)
pak1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (496 aa)
LOC103476383AP complex subunit beta. (953 aa)
LOC103465423Cell division cycle 42. (191 aa)
actbUncharacterized protein. (375 aa)
aph1aAPH1B gamma secretase subunit. (258 aa)
efnb2Ephrin-B2a; Belongs to the ephrin family. (313 aa)
epha8Uncharacterized protein. (1031 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
LOC103472698Ephrin-A1a; Belongs to the ephrin family. (221 aa)
LOC103472699Ephrin-A3a; Belongs to the ephrin family. (224 aa)
FMN1Formin 1. (1260 aa)
LOC103458010Tyrosine-protein kinase. (537 aa)
pak2Non-specific serine/threonine protein kinase. (525 aa)
LOC103467856Tyrosine-protein kinase. (542 aa)
efnb1Ephrin-B1; Belongs to the ephrin family. (376 aa)
LOC103463084Uncharacterized protein. (985 aa)
LOC103473962Glutamate receptor, ionotropic, N-methyl D-aspartate 1a. (964 aa)
ENSPREP00000032273Ephrin RBD domain-containing protein; Belongs to the ephrin family. (317 aa)
LOC103461943Eph receptor A6. (1058 aa)
vav2Vav 2 guanine nucleotide exchange factor. (793 aa)
MMP9Matrix metallopeptidase 9. (689 aa)
ap2s1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (141 aa)
PAK3Non-specific serine/threonine protein kinase. (575 aa)
ephb4Eph receptor B4a. (990 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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