(40 nodes) SUMOylation of transcription factors network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sp5	Sp5 transcription factor a. (375 aa)
	sumo2	Small ubiquitin-related modifier. (95 aa)
	zmiz1	Zinc finger MIZ-type containing 1. (1068 aa)
	foxd1	Forkhead box D1. (321 aa)
	sp4	Sp4 transcription factor. (765 aa)
	tfeb	Transcription factor EB. (522 aa)
	LOC103461250	BHLH domain-containing protein. (330 aa)
	MITF	Melanocyte inducing transcription factor b. (484 aa)
	SP3	Sp3a transcription factor. (699 aa)
	LOC103458727	Sp3b transcription factor. (680 aa)
	LOC103458735	Small ubiquitin-related modifier. (94 aa)
	LOC103462108	Protein inhibitor of activated STAT, 1a. (658 aa)
	pias4	Protein inhibitor of activated STAT, 4a. (509 aa)
	LOC103461674	Ubiquitin-like domain-containing protein. (161 aa)
	hic1	Hypermethylated in cancer 1. (752 aa)
	hic2	Hypermethylated in cancer 2. (586 aa)
	LOC103466533	Protein inhibitor of activated STAT, 1b. (647 aa)
	LOC103460179	Uncharacterized protein. (545 aa)
	LOC103463565	Forkhead box D2. (368 aa)
	ENSPREP00000017501	Rad60-SLD domain-containing protein. (78 aa)
	ENSPREP00000017515	Uncharacterized protein. (289 aa)
	ENSPREP00000018460	MITF_TFEB_C_3_N domain-containing protein. (119 aa)
	mta1	Metastasis associated 1. (584 aa)
	kctd2	Potassium channel tetramerization domain containing 2. (268 aa)
	LOC103468383	Zgc:162612. (320 aa)
	sumo1	Small ubiquitin like modifier 1. (205 aa)
	zmiz2	Zinc finger MIZ-type containing 2. (886 aa)
	LOC103467207	Zgc:194189. (263 aa)
	LOC103476831	SP-RING-type domain-containing protein. (905 aa)
	tfap2c	Transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma). (310 aa)
	LOC103467943	Small ubiquitin-related modifier. (96 aa)
	tp53bp1	Tumor protein p53 binding protein, 1. (1579 aa)
	LOC103470162	Forkhead box D5. (466 aa)
	ube2i	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	ENSPREP00000026439	Zinc finger, MIZ-type containing 2. (346 aa)
	LOC103468487	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	foxd3	Forkhead box D3. (363 aa)
	tfe3	Transcription factor binding to IGHM enhancer 3b. (490 aa)
	LOC103465526	Melanocyte inducing transcription factor a. (404 aa)
	LOC103467349	Sp5 transcription factor-like. (366 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000017501	ENSPREP00000026439	ENSPREP00000017501	ENSPREP00000026439	Rad60-SLD domain-containing protein.	Zinc finger, MIZ-type containing 2.	0.589
ENSPREP00000017501	LOC103460179	ENSPREP00000017501	ENSPREP00000016190	Rad60-SLD domain-containing protein.	Uncharacterized protein.	0.589
ENSPREP00000017501	LOC103462108	ENSPREP00000017501	ENSPREP00000011832	Rad60-SLD domain-containing protein.	Protein inhibitor of activated STAT, 1a.	0.589
ENSPREP00000017501	LOC103466533	ENSPREP00000017501	ENSPREP00000015982	Rad60-SLD domain-containing protein.	Protein inhibitor of activated STAT, 1b.	0.589
ENSPREP00000017501	LOC103468487	ENSPREP00000017501	ENSPREP00000027513	Rad60-SLD domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.732
ENSPREP00000017501	LOC103476831	ENSPREP00000017501	ENSPREP00000023653	Rad60-SLD domain-containing protein.	SP-RING-type domain-containing protein.	0.589
ENSPREP00000017501	kctd2	ENSPREP00000017501	ENSPREP00000019964	Rad60-SLD domain-containing protein.	Potassium channel tetramerization domain containing 2.	0.732
ENSPREP00000017501	pias4	ENSPREP00000017501	ENSPREP00000012849	Rad60-SLD domain-containing protein.	Protein inhibitor of activated STAT, 4a.	0.589
ENSPREP00000017501	tp53bp1	ENSPREP00000017501	ENSPREP00000025854	Rad60-SLD domain-containing protein.	Tumor protein p53 binding protein, 1.	0.614
ENSPREP00000017501	ube2i	ENSPREP00000017501	ENSPREP00000026310	Rad60-SLD domain-containing protein.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.732
ENSPREP00000017501	zmiz1	ENSPREP00000017501	ENSPREP00000003454	Rad60-SLD domain-containing protein.	Zinc finger MIZ-type containing 1.	0.589
ENSPREP00000017501	zmiz2	ENSPREP00000017501	ENSPREP00000022550	Rad60-SLD domain-containing protein.	Zinc finger MIZ-type containing 2.	0.589
ENSPREP00000017515	ENSPREP00000026439	ENSPREP00000017515	ENSPREP00000026439	Uncharacterized protein.	Zinc finger, MIZ-type containing 2.	0.589
ENSPREP00000017515	LOC103460179	ENSPREP00000017515	ENSPREP00000016190	Uncharacterized protein.	Uncharacterized protein.	0.589
ENSPREP00000017515	LOC103462108	ENSPREP00000017515	ENSPREP00000011832	Uncharacterized protein.	Protein inhibitor of activated STAT, 1a.	0.589
ENSPREP00000017515	LOC103466533	ENSPREP00000017515	ENSPREP00000015982	Uncharacterized protein.	Protein inhibitor of activated STAT, 1b.	0.589
ENSPREP00000017515	LOC103468487	ENSPREP00000017515	ENSPREP00000027513	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.761
ENSPREP00000017515	LOC103476831	ENSPREP00000017515	ENSPREP00000023653	Uncharacterized protein.	SP-RING-type domain-containing protein.	0.599
ENSPREP00000017515	kctd2	ENSPREP00000017515	ENSPREP00000019964	Uncharacterized protein.	Potassium channel tetramerization domain containing 2.	0.732
ENSPREP00000017515	pias4	ENSPREP00000017515	ENSPREP00000012849	Uncharacterized protein.	Protein inhibitor of activated STAT, 4a.	0.589