(38 nodes) Nuclear Pore Complex (NPC) Disassembly network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	nup210	Nucleoporin 210. (1869 aa)
	tpr	Translocated promoter region b, nuclear basket protein. (2383 aa)
	ccnb3	Cyclin B3; Belongs to the cyclin family. (475 aa)
	seh1l	SEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family. (357 aa)
	ndc1	NDC1 transmembrane nucleoporin. (669 aa)
	nek7	NIMA-related kinase 7; Belongs to the protein kinase superfamily. (330 aa)
	LOC103461037	RAN binding protein 2. (2831 aa)
	nup155	Nucleoporin 155. (1373 aa)
	ENSPREP00000021545	Uncharacterized protein. (255 aa)
	LOC103479306	Translocated promoter region a, nuclear basket protein. (1861 aa)
	sec13	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (370 aa)
	nup43	Nucleoporin 43. (344 aa)
	nup58	Nucleoporin 58. (601 aa)
	nup88	Nucleoporin 88. (720 aa)
	nup214	Nup214_FG domain-containing protein. (1849 aa)
	rae1	Ribonucleic acid export 1. (369 aa)
	LOC103476380	POM121 transmembrane nucleoporin. (1114 aa)
	wdr41	WD repeat domain 41. (449 aa)
	ccnb1	Cyclin B1; Belongs to the cyclin family. (401 aa)
	Nup205	Uncharacterized protein. (371 aa)
	ENSPREP00000030871	Uncharacterized protein. (312 aa)
	nup35	Nucleoporin 35. (282 aa)
	nup42	Nucleoporin 42. (474 aa)
	nup133	Nucleoporin 133. (1135 aa)
	ENSPREP00000032333	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (241 aa)
	nup93	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (822 aa)
	nup188	Nucleoporin 188. (1752 aa)
	nup85	Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (654 aa)
	nup98	Nucleoporin 98. (1820 aa)
	NUP54	Nucleoporin 54. (621 aa)
	nup160	Nucleoporin 160. (1398 aa)
	NUP62	Nucleoporin 62. (553 aa)
	LOC103474790	Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (355 aa)
	aaas	Achalasia, adrenocortical insufficiency, alacrimia. (518 aa)
	nup50	Nucleoporin 50. (447 aa)
	cdk1	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (308 aa)
	nup37	Nucleoporin 37. (347 aa)
	nup153	Nucleoporin 153. (1518 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000021545	ENSPREP00000030871	ENSPREP00000021545	ENSPREP00000030871	Uncharacterized protein.	Uncharacterized protein.	0.737
ENSPREP00000021545	ENSPREP00000032333	ENSPREP00000021545	ENSPREP00000032333	Uncharacterized protein.	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	0.883
ENSPREP00000021545	LOC103461037	ENSPREP00000021545	ENSPREP00000019992	Uncharacterized protein.	RAN binding protein 2.	0.970
ENSPREP00000021545	LOC103479306	ENSPREP00000021545	ENSPREP00000021669	Uncharacterized protein.	Translocated promoter region a, nuclear basket protein.	0.941
ENSPREP00000021545	NUP54	ENSPREP00000021545	ENSPREP00000004836	Uncharacterized protein.	Nucleoporin 54.	0.762
ENSPREP00000021545	NUP62	ENSPREP00000021545	ENSPREP00000007080	Uncharacterized protein.	Nucleoporin 62.	0.704
ENSPREP00000021545	Nup205	ENSPREP00000021545	ENSPREP00000030838	Uncharacterized protein.	Uncharacterized protein.	0.786
ENSPREP00000021545	aaas	ENSPREP00000021545	ENSPREP00000009197	Uncharacterized protein.	Achalasia, adrenocortical insufficiency, alacrimia.	0.750
ENSPREP00000021545	ndc1	ENSPREP00000021545	ENSPREP00000016988	Uncharacterized protein.	NDC1 transmembrane nucleoporin.	0.603
ENSPREP00000021545	nup133	ENSPREP00000021545	ENSPREP00000032294	Uncharacterized protein.	Nucleoporin 133.	0.815
ENSPREP00000021545	nup153	ENSPREP00000021545	ENSPREP00000010926	Uncharacterized protein.	Nucleoporin 153.	0.886
ENSPREP00000021545	nup155	ENSPREP00000021545	ENSPREP00000020739	Uncharacterized protein.	Nucleoporin 155.	0.803
ENSPREP00000021545	nup160	ENSPREP00000021545	ENSPREP00000005366	Uncharacterized protein.	Nucleoporin 160.	0.663
ENSPREP00000021545	nup188	ENSPREP00000021545	ENSPREP00000001758	Uncharacterized protein.	Nucleoporin 188.	0.677
ENSPREP00000021545	nup210	ENSPREP00000021545	ENSPREP00000012590	Uncharacterized protein.	Nucleoporin 210.	0.652
ENSPREP00000021545	nup214	ENSPREP00000021545	ENSPREP00000024544	Uncharacterized protein.	Nup214_FG domain-containing protein.	0.802
ENSPREP00000021545	nup35	ENSPREP00000021545	ENSPREP00000031014	Uncharacterized protein.	Nucleoporin 35.	0.686
ENSPREP00000021545	nup37	ENSPREP00000021545	ENSPREP00000010359	Uncharacterized protein.	Nucleoporin 37.	0.639
ENSPREP00000021545	nup42	ENSPREP00000021545	ENSPREP00000031678	Uncharacterized protein.	Nucleoporin 42.	0.650
ENSPREP00000021545	nup43	ENSPREP00000021545	ENSPREP00000023665	Uncharacterized protein.	Nucleoporin 43.	0.649