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| | ccna1 | Cyclin A1; Belongs to the cyclin family. (402 aa) |
| | ENSPREP00000000287 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa) |
| | LOC103472958 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | KPNA2 | Importin subunit alpha; Belongs to the importin alpha family. (525 aa) |
| | LOC103467755 | Importin subunit alpha; Belongs to the importin alpha family. (512 aa) |
| | slx4 | SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1463 aa) |
| | Sirt7 | Uncharacterized protein. (134 aa) |
| | poll | Polymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (599 aa) |
| | ENSPREP00000001588 | Ubiquitin-conjugating enzyme E2 variant 1. (146 aa) |
| | parp1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa) |
| | rad51 | RAD51 recombinase. (219 aa) |
| | parp2 | Poly [ADP-ribose] polymerase. (647 aa) |
| | sumo2 | Small ubiquitin-related modifier. (95 aa) |
| | ENSPREP00000003697 | Uncharacterized protein. (168 aa) |
| | dntt | DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (497 aa) |
| | cdca7l | Cell division cycle associated 7b. (397 aa) |
| | polk | Polymerase (DNA directed) kappa. (880 aa) |
| | Xrcc4 | Uncharacterized protein. (159 aa) |
| | LOC103480107 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (263 aa) |
| | tdp1 | Tyrosyl-DNA phosphodiesterase 1. (622 aa) |
| | rfc2 | Replication factor C (activator 1) 2. (357 aa) |
| | babam2 | BRISC and BRCA1 A complex member 2. (386 aa) |
| | ENSPREP00000006911 | Uncharacterized protein. (216 aa) |
| | rfc5 | Replication factor C (activator 1) 5. (335 aa) |
| | ENSPREP00000007029 | Uncharacterized protein. (115 aa) |
| | ENSPREP00000007137 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa) |
| | pole2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa) |
| | cdca7 | Cell division cycle associated 7a. (403 aa) |
| | slf1 | SMC5-SMC6 complex localization factor 1. (880 aa) |
| | rpa2 | Replication protein A2. (256 aa) |
| | ENSPREP00000007704 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (98 aa) |
| | topbp1 | DNA topoisomerase II binding protein 1. (1453 aa) |
| | ENSPREP00000007848 | Histone H2B; Belongs to the histone H2B family. (119 aa) |
| | ENSPREP00000007980 | Reverse transcriptase domain-containing protein. (282 aa) |
| | ENSPREP00000008127 | Reverse transcriptase domain-containing protein. (1242 aa) |
| | ENSPREP00000008303 | Reverse transcriptase domain-containing protein. (353 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1355 aa) |
| | ENSPREP00000008908 | Histone H2B; Belongs to the histone H2B family. (134 aa) |
| | LOC103458261 | Nuclear receptor binding SET domain protein 2. (472 aa) |
| | ENSPREP00000009062 | Si:ch211-113a14.22; Belongs to the histone H2B family. (119 aa) |
| | LOC103458735 | Small ubiquitin-related modifier. (94 aa) |
| | ENSPREP00000009448 | Histone H2B; Belongs to the histone H2B family. (110 aa) |
| | ENSPREP00000009489 | Zgc:163040. (93 aa) |
| | polq | Polymerase (DNA directed), theta. (2656 aa) |
| | ENSPREP00000009572 | Reverse transcriptase domain-containing protein. (554 aa) |
| | ubb | Uncharacterized protein. (179 aa) |
| | ENSPREP00000009934 | Uncharacterized protein; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (65 aa) |
| | ENSPREP00000009961 | annotation not available (65 aa) |
| | ENSPREP00000009964 | Ubiquitin-like domain-containing protein. (95 aa) |
| | ccna2 | Cyclin A2; Belongs to the cyclin family. (434 aa) |
| | lig4 | DNA ligase. (908 aa) |
| | ppp4c | Serine/threonine-protein phosphatase. (330 aa) |
| | rfc1 | Replication factor C subunit 1. (1090 aa) |
| | LOC103479103 | Zgc:110269. (322 aa) |
| | ENSPREP00000011248 | Histone H2B; Belongs to the histone H2B family. (120 aa) |
| | blm | BLM RecQ like helicase. (1399 aa) |
| | tdp2 | Tyrosyl-DNA phosphodiesterase 2b. (359 aa) |
| | RCBTB1 | RCC1 and BTB domain containing protein 1. (531 aa) |
| | LOC103463436 | Lysine (K)-specific demethylase 4B. (1212 aa) |
| | LOC103479695 | Histone H2B; Belongs to the histone H2B family. (116 aa) |
| | rmi2 | RecQ mediated genome instability 2. (146 aa) |
| | tipin | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (254 aa) |
| | rnf8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (490 aa) |
| | apbb1 | Amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65). (797 aa) |
| | exd2 | Exonuclease 3'-5' domain containing 2. (644 aa) |
| | ube2v2 | Ubiquitin-conjugating enzyme E2 variant 2. (149 aa) |
| | SPIDR | Scaffold protein involved in DNA repair. (934 aa) |
| | ENSPREP00000012739 | Histone H2B; Belongs to the histone H2B family. (120 aa) |
| | pias4 | Protein inhibitor of activated STAT, 4a. (509 aa) |
| | ENSPREP00000012897 | Histone H2B; Belongs to the histone H2B family. (140 aa) |
| | ENSPREP00000013045 | Histone H2B; Belongs to the histone H2B family. (157 aa) |
| | ENSPREP00000013055 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (149 aa) |
| | LOC103461674 | Ubiquitin-like domain-containing protein. (161 aa) |
| | pole3 | Polymerase (DNA directed), epsilon 3 (p17 subunit). (173 aa) |
| | tmem182 | Transmembrane protein 182a. (246 aa) |
| | prkdc | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (3907 aa) |
| | dna2 | Uncharacterized protein. (1328 aa) |
| | parp3 | Poly [ADP-ribose] polymerase. (522 aa) |
| | xrcc5 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (731 aa) |
| | ENSPREP00000014560 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (483 aa) |
| | pold2 | Polymerase (DNA directed), delta 2, regulatory subunit. (471 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (674 aa) |
| | cnppd1 | Cyclin Pas1/PHO80 domain containing 1. (430 aa) |
| | Ankrd12 | ANK_REP_REGION domain-containing protein. (423 aa) |
| | LOC103474198 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (537 aa) |
| | hus1 | Checkpoint protein; Belongs to the HUS1 family. (245 aa) |
| | ENSPREP00000015300 | Reverse transcriptase domain-containing protein. (415 aa) |
| | rbbp8 | Uncharacterized protein. (647 aa) |
| | xrcc2 | X-ray repair cross complementing 2. (292 aa) |
| | rfc3 | Replication factor C (activator 1) 3. (356 aa) |
| | rad17 | RAD17 checkpoint clamp loader component. (705 aa) |
| | eya4 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (613 aa) |
| | LOC103475329 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (531 aa) |
| | uba52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa) |
| | atr | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2589 aa) |
| | paxip1 | PAX interacting (with transcription-activation domain) protein 1. (1084 aa) |
| | ube2n | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa) |
| | xrcc3 | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (302 aa) |
| | pcna | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa) |
| | recql4 | RecQ helicase-like 4. (1237 aa) |
| | brca2 | BRCA2 DNA repair associated. (3038 aa) |
| | rps27a | Ribosomal protein S27a. (156 aa) |
| | abraxas1 | Abraxas 1, BRCA1 A complex subunit. (349 aa) |
| | babam1 | BRISC and BRCA1 A complex member 1. (355 aa) |
| | ENSPREP00000018722 | Reverse transcriptase domain-containing protein. (253 aa) |
| | rfc4 | Replication factor C (activator 1) 4. (357 aa) |
| | pole4 | Polymerase (DNA-directed), epsilon 4, accessory subunit. (145 aa) |
| | rpa3 | Replication protein A3. (122 aa) |
| | rad51c | RAD51 paralog C. (377 aa) |
| | mdc1 | Uncharacterized protein. (2088 aa) |
| | tp53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (342 aa) |
| | LOC103473172 | X-ray repair complementing defective repair in Chinese hamster cells 4. (340 aa) |
| | pold1 | DNA polymerase. (1102 aa) |
| | rad51d | RAD51 paralog D. (350 aa) |
| | lig3 | DNA ligase. (997 aa) |
| | cdk2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | LOC103473189 | Uncharacterized protein. (154 aa) |
| | abl1 | Tyrosine-protein kinase. (1124 aa) |
| | LOC103475008 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (553 aa) |
| | timeless | Timeless circadian clock. (1173 aa) |
| | atrip | Uncharacterized protein. (763 aa) |
| | nhej1 | Nonhomologous end-joining factor 1. (315 aa) |
| | sumo1 | Small ubiquitin like modifier 1. (205 aa) |
| | polh | Polymerase (DNA directed), eta. (716 aa) |
| | LOC103468400 | Importin subunit alpha; Belongs to the importin alpha family. (520 aa) |
| | polm | DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (502 aa) |
| | meiob | Methionine sulfoxide reductase B1b. (464 aa) |
| | mus81 | MUS81 structure-specific endonuclease subunit. (616 aa) |
| | xrcc1 | X-ray repair complementing defective repair in Chinese hamster cells 1. (619 aa) |
| | ENSPREP00000023621 | Uncharacterized protein. (277 aa) |
| | rad9b | RAD9 checkpoint clamp component B. (442 aa) |
| | rad52 | RAD52 homolog, DNA repair protein. (343 aa) |
| | LOC103464861 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (493 aa) |
| | chek2 | Checkpoint kinase 2. (510 aa) |
| | LOC103473596 | Transmembrane protein 182b. (260 aa) |
| | nbn | Nibrin. (843 aa) |
| | atm | Non-specific serine/threonine protein kinase. (3091 aa) |
| | LOC103467943 | Small ubiquitin-related modifier. (96 aa) |
| | ENSPREP00000024682 | KxDL motif containing 1. (197 aa) |
| | LOC103482091 | Essential meiotic structure-specific endonuclease 1. (232 aa) |
| | chek1 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (478 aa) |
| | rad1 | RAD1 homolog (S. pombe). (279 aa) |
| | tp53bp1 | Tumor protein p53 binding protein, 1. (1579 aa) |
| | rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (387 aa) |
| | LOC103479463 | Sirtuin 6. (339 aa) |
| | uimc1 | Uncharacterized protein. (985 aa) |
| | fen1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (396 aa) |
| | ube2i | Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) |
| | LOC103466094 | Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (209 aa) |
| | eya1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa) |
| | top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1019 aa) |
| | ppp5c | Serine/threonine-protein phosphatase. (472 aa) |
| | exo1 | Exonuclease 1. (757 aa) |
| | baz1b | Bromodomain adjacent to zinc finger domain, 1B. (1647 aa) |
| | LOC103468487 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) |
| | EME2 | ERCC4 domain-containing protein. (370 aa) |
| | rif1 | Replication timing regulatory factor 1. (2323 aa) |
| | LOC103467542 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | ENSPREP00000027944 | Reverse transcriptase domain-containing protein. (1281 aa) |
| | rmi1 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (671 aa) |
| | pold3 | Polymerase (DNA-directed), delta 3, accessory subunit. (438 aa) |
| | Brcc3 | BRCA1/BRCA2-containing complex, subunit 3. (251 aa) |
| | ENSPREP00000029980 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (95 aa) |
| | ENSPREP00000030043 | Histone H2B; Belongs to the histone H2B family. (161 aa) |
| | ENSPREP00000030473 | Uncharacterized protein. (225 aa) |
| | xrcc6 | X-ray repair complementing defective repair in Chinese hamster cells 6. (655 aa) |
| | tdrd3 | Tudor domain containing 3. (786 aa) |
| | ENSPREP00000031399 | Ring finger protein 168. (425 aa) |
| | dclre1c | DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae). (576 aa) |
| | LOC103470930 | Uncharacterized protein. (250 aa) |
| | rhno1 | Si:ch73-352p4.5. (221 aa) |
| | brca1 | Uncharacterized protein. (1344 aa) |
| | ppp4r2 | Protein phosphatase 4, regulatory subunit 2b. (415 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1114 aa) |
| | ENSPREP00000033302 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (361 aa) |
| | ankrd11 | Ankyrin repeat domain 11. (2822 aa) |
| | pold4 | Uncharacterized protein. (89 aa) |
| | mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (611 aa) |
| | ENSPREP00000033770 | RAD51_interact domain-containing protein. (289 aa) |
| | LOC103474640 | Histone H2A; Belongs to the histone H2A family. (138 aa) |
| | kat5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (560 aa) |
| | smarca5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1037 aa) |
