(37 nodes) Inflammasomes network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	panx1	Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (384 aa)
	sugt1	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone. (323 aa)
	ENSPREP00000003758	Pyrin domain-containing protein. (110 aa)
	ENSPREP00000003810	Uncharacterized protein. (206 aa)
	LOC103477730	Uncharacterized protein. (193 aa)
	pstpip2	Proline-serine-threonine phosphatase interacting protein 2. (338 aa)
	ENSPREP00000004899	Uncharacterized protein. (565 aa)
	ENSPREP00000005851	Arrestin_C domain-containing protein. (305 aa)
	LOC103470435	Arrestin_C domain-containing protein. (374 aa)
	arrdc1	Arrestin domain containing 1b. (436 aa)
	LOC103466606	Proline-serine-threonine phosphatase interacting protein 1a. (410 aa)
	arrdc3	Arrestin domain containing 3a. (412 aa)
	LOC108166548	Arrestin_C domain-containing protein. (477 aa)
	LOC103470654	Arrestin_C domain-containing protein. (382 aa)
	ENSPREP00000006378	Thioredoxin domain-containing protein. (133 aa)
	LOC103466909	BH4_2 domain-containing protein. (231 aa)
	LOC103475976	Thioredoxin; Belongs to the thioredoxin family. (103 aa)
	LOC103475974	Thioredoxin; Belongs to the thioredoxin family. (132 aa)
	bcl2	BCL2 apoptosis regulator b. (230 aa)
	LOC103470436	Arrestin_C domain-containing protein. (321 aa)
	LOC103470653	Arrestin_C domain-containing protein. (313 aa)
	LOC108166556	Arrestin_C domain-containing protein. (291 aa)
	hsp90ab1	Heat shock protein 90, alpha (cytosolic), class B member 1. (723 aa)
	LOC103461755	NME/NM23 family member 8; Belongs to the NDK family. (491 aa)
	p2rx7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (580 aa)
	LOC103469597	Arrestin domain containing 1a. (457 aa)
	LOC103473176	Arrestin domain containing 3b. (418 aa)
	LOC103477461	Arrestin_C domain-containing protein. (507 aa)
	LOC103475074	Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (436 aa)
	txnip	Thioredoxin interacting protein. (408 aa)
	ENSPREP00000030231	Uncharacterized protein. (800 aa)
	ENSPREP00000030263	Uncharacterized protein. (812 aa)
	ENSPREP00000030269	Uncharacterized protein. (785 aa)
	ENSPREP00000014094	NDK domain-containing protein. (133 aa)
	arrdc2	Arrestin domain containing 2. (409 aa)
	ENSPREP00000016502	Arrestin_N domain-containing protein. (126 aa)
	BCL2L1	BCL2 like 1. (217 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL2L1	ENSPREP00000030231	ENSPREP00000032815	ENSPREP00000030231	BCL2 like 1.	Uncharacterized protein.	0.620
BCL2L1	ENSPREP00000030263	ENSPREP00000032815	ENSPREP00000030263	BCL2 like 1.	Uncharacterized protein.	0.620
BCL2L1	ENSPREP00000030269	ENSPREP00000032815	ENSPREP00000030269	BCL2 like 1.	Uncharacterized protein.	0.620
BCL2L1	LOC103466909	ENSPREP00000032815	ENSPREP00000006369	BCL2 like 1.	BH4_2 domain-containing protein.	0.903
BCL2L1	bcl2	ENSPREP00000032815	ENSPREP00000006116	BCL2 like 1.	BCL2 apoptosis regulator b.	0.957
ENSPREP00000003810	ENSPREP00000030231	ENSPREP00000003810	ENSPREP00000030231	Uncharacterized protein.	Uncharacterized protein.	0.413
ENSPREP00000003810	ENSPREP00000030263	ENSPREP00000003810	ENSPREP00000030263	Uncharacterized protein.	Uncharacterized protein.	0.413
ENSPREP00000003810	ENSPREP00000030269	ENSPREP00000003810	ENSPREP00000030269	Uncharacterized protein.	Uncharacterized protein.	0.413
ENSPREP00000003810	LOC103466606	ENSPREP00000003810	ENSPREP00000011927	Uncharacterized protein.	Proline-serine-threonine phosphatase interacting protein 1a.	0.511
ENSPREP00000003810	LOC103477730	ENSPREP00000003810	ENSPREP00000003858	Uncharacterized protein.	Uncharacterized protein.	0.571
ENSPREP00000003810	pstpip2	ENSPREP00000003810	ENSPREP00000004251	Uncharacterized protein.	Proline-serine-threonine phosphatase interacting protein 2.	0.412
ENSPREP00000005851	ENSPREP00000006378	ENSPREP00000005851	ENSPREP00000006378	Arrestin_C domain-containing protein.	Thioredoxin domain-containing protein.	0.447
ENSPREP00000005851	ENSPREP00000014094	ENSPREP00000005851	ENSPREP00000014094	Arrestin_C domain-containing protein.	NDK domain-containing protein.	0.471
ENSPREP00000005851	LOC103461755	ENSPREP00000005851	ENSPREP00000014080	Arrestin_C domain-containing protein.	NME/NM23 family member 8; Belongs to the NDK family.	0.447
ENSPREP00000005851	LOC103475974	ENSPREP00000005851	ENSPREP00000006218	Arrestin_C domain-containing protein.	Thioredoxin; Belongs to the thioredoxin family.	0.447
ENSPREP00000005851	LOC103475976	ENSPREP00000005851	ENSPREP00000006289	Arrestin_C domain-containing protein.	Thioredoxin; Belongs to the thioredoxin family.	0.447
ENSPREP00000006378	ENSPREP00000005851	ENSPREP00000006378	ENSPREP00000005851	Thioredoxin domain-containing protein.	Arrestin_C domain-containing protein.	0.447
ENSPREP00000006378	ENSPREP00000016502	ENSPREP00000006378	ENSPREP00000016502	Thioredoxin domain-containing protein.	Arrestin_N domain-containing protein.	0.598
ENSPREP00000006378	LOC103469597	ENSPREP00000006378	ENSPREP00000019620	Thioredoxin domain-containing protein.	Arrestin domain containing 1a.	0.598
ENSPREP00000006378	LOC103470435	ENSPREP00000006378	ENSPREP00000005880	Thioredoxin domain-containing protein.	Arrestin_C domain-containing protein.	0.447