STRINGSTRING
cdk7 cdk7 polr2c polr2c LOC103459886 LOC103459886 eaf2 eaf2 aff1 aff1 taf13 taf13 nelfa nelfa polr2i polr2i ccnh ccnh gtf2h5 gtf2h5 mllt3 mllt3 cinp cinp Taf12 Taf12 aff4 aff4 taf11 taf11 ccnq ccnq cdc73 cdc73 NCBP1 NCBP1 POLR2E POLR2E supt5h supt5h polr2h polr2h IWS1 IWS1 Cdk9 Cdk9 gtf2b gtf2b ENSPREP00000011339 ENSPREP00000011339 TAF4 TAF4 taf3 taf3 supt4h1 supt4h1 eloa eloa ENSPREP00000012074 ENSPREP00000012074 LOC103478445 LOC103478445 ENSPREP00000012814 ENSPREP00000012814 mllt1 mllt1 gtf2a2 gtf2a2 supt16h supt16h ell ell supt6h supt6h tbp tbp LOC103468942 LOC103468942 paf1 paf1 gtf2e2 gtf2e2 taf2 taf2 tbpl1 tbpl1 polr2b polr2b taf7l taf7l tceanc2 tceanc2 LOC103470674 LOC103470674 Tceanc Tceanc wdr61 wdr61 polr2a polr2a nelfcd nelfcd nelfb nelfb Clg8h11orf88 Clg8h11orf88 gtf2h1 gtf2h1 ENSPREP00000019960 ENSPREP00000019960 eloc eloc LOC103461004 LOC103461004 gtf2e1 gtf2e1 polr2j polr2j mnat1 mnat1 LOC103481886 LOC103481886 tcea1 tcea1 ccnt2 ccnt2 LOC103465090 LOC103465090 Ctdp1 Ctdp1 polr2g polr2g polr2f polr2f LOC103466384 LOC103466384 taf10 taf10 ccnk ccnk ssrp1 ssrp1 gtf2a1 gtf2a1 leo1 leo1 rtf1 rtf1 eaf1 eaf1 ercc2 ercc2 LOC103467918 LOC103467918 ccnt1 ccnt1 gtf2h4 gtf2h4 LOC103478624 LOC103478624 gtf2h3 gtf2h3 gtf2f2 gtf2f2 ercc3 ercc3 ncbp2 ncbp2 polr2d polr2d taf5l taf5l LOC103475759 LOC103475759 ENSPREP00000032704 ENSPREP00000032704 taf6 taf6 slc39a13 slc39a13 polr2l polr2l ELOB ELOB ENSPREP00000034063 ENSPREP00000034063 ctr9 ctr9 taf5 taf5 ENSPREP00000001027 ENSPREP00000001027 nelfe nelfe ENSPREP00000003308 ENSPREP00000003308 tbpl2 tbpl2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (387 aa)
polr2cPolymerase (RNA) II (DNA directed) polypeptide C. (273 aa)
LOC103459886TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (253 aa)
eaf2ELL associated factor 2. (255 aa)
aff1Uncharacterized protein. (1096 aa)
taf13TATA-box binding protein associated factor 13. (188 aa)
nelfaNegative elongation factor complex member A. (547 aa)
polr2iDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
ccnhCyclin H; Belongs to the cyclin family. (319 aa)
gtf2h5General transcription factor IIH, polypeptide 5. (71 aa)
mllt3MLLT3 super elongation complex subunit. (507 aa)
cinpCyclin-dependent kinase 2 interacting protein. (209 aa)
Taf12TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (159 aa)
aff4AF4/FMR2 family, member 4. (1106 aa)
taf11TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (196 aa)
ccnqCyclin Q; Belongs to the cyclin family. (252 aa)
cdc73Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). (576 aa)
NCBP1Nuclear cap binding protein subunit 1. (797 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
supt5hTranscription elongation factor SPT5. (1059 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
IWS1Interacts with SUPT6H, CTD assembly factor 1. (766 aa)
Cdk9Cyclin-dependent kinase 9 (CDC2-related kinase). (552 aa)
gtf2bGeneral transcription factor IIB. (318 aa)
ENSPREP00000011339TAF4 domain-containing protein. (249 aa)
TAF4TATA-box binding protein associated factor 4. (878 aa)
taf3TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto. (896 aa)
supt4h1SPT4 homolog, DSIF elongation factor subunit. (174 aa)
eloaElongin A. (681 aa)
ENSPREP00000012074CYCLIN domain-containing protein; Belongs to the cyclin family. (177 aa)
LOC103478445Transcription elongation factor A (SII), 3. (562 aa)
ENSPREP00000012814Uncharacterized protein. (74 aa)
mllt1MLLT1 super elongation complex subunit a. (586 aa)
gtf2a2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
supt16hSPT16 homolog, facilitates chromatin remodeling subunit. (1077 aa)
ellElongation factor RNA polymerase II. (611 aa)
supt6hTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1825 aa)
tbpTATA box binding protein. (301 aa)
LOC103468942Elongin B. (117 aa)
paf1PAF1 homolog, Paf1/RNA polymerase II complex component. (531 aa)
gtf2e2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (287 aa)
taf2TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (1119 aa)
tbpl1TBP-like 1. (187 aa)
polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
taf7lTAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (383 aa)
tceanc2Uncharacterized protein. (206 aa)
LOC103470674General transcription factor IIH subunit. (420 aa)
TceancUncharacterized protein. (355 aa)
wdr61WD repeat domain 61. (305 aa)
polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1966 aa)
nelfcdNegative elongation factor complex member C/D. (578 aa)
nelfbNegative elongation factor complex member B. (587 aa)
Clg8h11orf88Uncharacterized protein. (152 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (550 aa)
ENSPREP00000019960WD_REPEATS_REGION domain-containing protein. (326 aa)
elocElongin C paralog a; Belongs to the SKP1 family. (112 aa)
LOC103461004General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (267 aa)
gtf2e1General transcription factor IIE, polypeptide 1, alpha. (462 aa)
polr2jPolymerase (RNA) II (DNA directed) polypeptide J. (117 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
LOC103481886Uncharacterized protein. (302 aa)
tcea1Transcription elongation factor A (SII), 1. (320 aa)
ccnt2Cyclin T2; Belongs to the cyclin family. (687 aa)
LOC103465090TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor. (852 aa)
Ctdp1FCP1 homology domain-containing protein. (271 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (172 aa)
polr2fPolymerase (RNA) II (DNA directed) polypeptide F. (98 aa)
LOC103466384TAFH domain-containing protein. (863 aa)
taf10TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (186 aa)
ccnkCyclin K; Belongs to the cyclin family. (541 aa)
ssrp1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (730 aa)
gtf2a1General transcription factor IIA, 1. (393 aa)
leo1LEO1 homolog, Paf1/RNA polymerase II complex component. (631 aa)
rtf1RTF1 homolog, Paf1/RNA polymerase II complex component. (663 aa)
eaf1EAF domain-containing protein. (282 aa)
ercc2Excision repair cross-complementation group 2. (655 aa)
LOC103467918Transcription elongation factor A (SII), 2. (369 aa)
ccnt1Cyclin T1; Belongs to the cyclin family. (189 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (434 aa)
LOC103478624Si:dkey-12j5.1. (361 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (277 aa)
gtf2f2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (312 aa)
ercc3Excision repair cross-complementation group 3. (783 aa)
ncbp2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (194 aa)
polr2dPolymerase (RNA) II (DNA directed) polypeptide D. (104 aa)
taf5lTAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor. (599 aa)
LOC103475759Transcription initiation factor TFIID subunit. (1985 aa)
ENSPREP00000032704TFIIS N-terminal domain-containing protein. (269 aa)
taf6TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (637 aa)
slc39a13Solute carrier family 39 member 13. (381 aa)
polr2lPolymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
ELOBElongin B. (119 aa)
ENSPREP00000034063General transcription factor IIA, 1-like. (327 aa)
ctr9CTR9 homolog, Paf1/RNA polymerase II complex component. (1154 aa)
taf5TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (745 aa)
ENSPREP00000001027Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (467 aa)
nelfeNegative elongation factor complex member E. (325 aa)
ENSPREP00000003308Uncharacterized protein. (202 aa)
tbpl2Uncharacterized protein. (307 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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