62 items (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	xpa	Xeroderma pigmentosum, complementation group A. (275 aa)
	ppie	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (301 aa)
	prpf19	Pre-mRNA processing factor 19. (458 aa)
	cdk7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (387 aa)
	polr2c	Polymerase (RNA) II (DNA directed) polypeptide C. (273 aa)
	polr2i	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
	ccnh	Cyclin H; Belongs to the cyclin family. (319 aa)
	gtf2h5	General transcription factor IIH, polypeptide 5. (71 aa)
	ddb1	Damage-specific DNA binding protein 1. (1102 aa)
	xab2	XPA binding protein 2. (912 aa)
	gps1	G protein pathway suppressor 1. (486 aa)
	POLR2E	RNA polymerase II subunit E. (210 aa)
	ubb	Uncharacterized protein. (179 aa)
	ENSPREP00000009964	Ubiquitin-like domain-containing protein. (95 aa)
	aqr	Aquarius intron-binding spliceosomal factor. (1325 aa)
	polr2h	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	LOC103478445	Transcription elongation factor A (SII), 3. (562 aa)
	cops2	COP9 signalosome subunit 2. (448 aa)
	ENSPREP00000012814	Uncharacterized protein. (74 aa)
	nrde2	NRDE-2, necessary for RNA interference, domain containing. (1204 aa)
	ZNF830	Zinc finger protein 830. (333 aa)
	LOC103476136	Si:ch73-1a9.3. (82 aa)
	polr2b	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	tceanc2	Uncharacterized protein. (206 aa)
	cul4b	Cullin 4B; Belongs to the cullin family. (872 aa)
	LOC103470674	General transcription factor IIH subunit. (420 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	Tceanc	Uncharacterized protein. (355 aa)
	cops7a	COP9 constitutive photomorphogenic homolog subunit 7A. (268 aa)
	polr2a	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1966 aa)
	gtf2h1	General transcription factor IIH, polypeptide 1. (550 aa)
	COPS6	COP9 signalosome subunit 6. (316 aa)
	ENSPREP00000020872	Uncharacterized protein. (76 aa)
	LOC103473189	Uncharacterized protein. (154 aa)
	LOC103460347	ISY1 splicing factor homolog. (235 aa)
	polr2j	Polymerase (RNA) II (DNA directed) polypeptide J. (117 aa)
	mnat1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
	tcea1	Transcription elongation factor A (SII), 1. (320 aa)
	polr2g	Polymerase (RNA) II (DNA directed) polypeptide G-like. (172 aa)
	ENSPREP00000024682	KxDL motif containing 1. (197 aa)
	polr2f	Polymerase (RNA) II (DNA directed) polypeptide F. (98 aa)
	ercc8	Excision repair cross-complementation group 8. (401 aa)
	rbx1	Ring-box 1, E3 ubiquitin protein ligase. (108 aa)
	LOC103468460	E1A binding protein p300 b. (2737 aa)
	cops4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis). (406 aa)
	ercc2	Excision repair cross-complementation group 2. (655 aa)
	LOC103467918	Transcription elongation factor A (SII), 2. (369 aa)
	usp7	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1186 aa)
	gtf2h4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (434 aa)
	ppp1r42	Protein phosphatase 1, regulatory subunit 42. (291 aa)
	cops5	COP9 signalosome subunit 5. (338 aa)
	gtf2h3	General transcription factor IIH, polypeptide 3. (277 aa)
	LOC103482005	E1A binding protein p300 a. (2743 aa)
	ercc3	Excision repair cross-complementation group 3. (783 aa)
	ercc6	Excision repair cross-complementation group 6. (1402 aa)
	cul4a	Cullin 4A; Belongs to the cullin family. (591 aa)
	cops3	COP9 signalosome subunit 3. (423 aa)
	polr2d	Polymerase (RNA) II (DNA directed) polypeptide D. (104 aa)
	hmgn5	High mobility group nucleosome binding domain 6. (81 aa)
	LOC103470988	UV-stimulated scaffold protein A. (688 aa)
	polr2l	Polymerase (RNA) II (DNA directed) polypeptide L. (67 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COPS6	ENSPREP00000009964	ENSPREP00000020740	ENSPREP00000009964	COP9 signalosome subunit 6.	Ubiquitin-like domain-containing protein.	0.683
COPS6	ENSPREP00000012814	ENSPREP00000020740	ENSPREP00000012814	COP9 signalosome subunit 6.	Uncharacterized protein.	0.666
COPS6	ENSPREP00000020872	ENSPREP00000020740	ENSPREP00000020872	COP9 signalosome subunit 6.	Uncharacterized protein.	0.997
COPS6	LOC103470674	ENSPREP00000020740	ENSPREP00000017962	COP9 signalosome subunit 6.	General transcription factor IIH subunit.	0.663
COPS6	LOC103473189	ENSPREP00000020740	ENSPREP00000021152	COP9 signalosome subunit 6.	Uncharacterized protein.	0.749
COPS6	POLR2E	ENSPREP00000020740	ENSPREP00000009571	COP9 signalosome subunit 6.	RNA polymerase II subunit E.	0.723
COPS6	ccnh	ENSPREP00000020740	ENSPREP00000006353	COP9 signalosome subunit 6.	Cyclin H; Belongs to the cyclin family.	0.694
COPS6	cops2	ENSPREP00000020740	ENSPREP00000012728	COP9 signalosome subunit 6.	COP9 signalosome subunit 2.	0.999
COPS6	cops3	ENSPREP00000020740	ENSPREP00000032020	COP9 signalosome subunit 6.	COP9 signalosome subunit 3.	0.999
COPS6	cops4	ENSPREP00000020740	ENSPREP00000026999	COP9 signalosome subunit 6.	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis).	0.999
COPS6	cops5	ENSPREP00000020740	ENSPREP00000029721	COP9 signalosome subunit 6.	COP9 signalosome subunit 5.	0.998
COPS6	cops7a	ENSPREP00000020740	ENSPREP00000018791	COP9 signalosome subunit 6.	COP9 constitutive photomorphogenic homolog subunit 7A.	0.996
COPS6	cul4a	ENSPREP00000020740	ENSPREP00000031714	COP9 signalosome subunit 6.	Cullin 4A; Belongs to the cullin family.	0.898
COPS6	cul4b	ENSPREP00000020740	ENSPREP00000017778	COP9 signalosome subunit 6.	Cullin 4B; Belongs to the cullin family.	0.898
COPS6	ddb1	ENSPREP00000020740	ENSPREP00000006475	COP9 signalosome subunit 6.	Damage-specific DNA binding protein 1.	0.902
COPS6	ercc2	ENSPREP00000020740	ENSPREP00000028527	COP9 signalosome subunit 6.	Excision repair cross-complementation group 2.	0.671
COPS6	ercc3	ENSPREP00000020740	ENSPREP00000030919	COP9 signalosome subunit 6.	Excision repair cross-complementation group 3.	0.673
COPS6	ercc6	ENSPREP00000020740	ENSPREP00000031633	COP9 signalosome subunit 6.	Excision repair cross-complementation group 6.	0.672
COPS6	ercc8	ENSPREP00000020740	ENSPREP00000026087	COP9 signalosome subunit 6.	Excision repair cross-complementation group 8.	0.768
COPS6	gps1	ENSPREP00000020740	ENSPREP00000008916	COP9 signalosome subunit 6.	G protein pathway suppressor 1.	0.999