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hagh hagh HAGHL HAGHL LOC103460042 LOC103460042 fam114a1 fam114a1 LOC103466626 LOC103466626 idh3a idh3a LOC103465809 LOC103465809 LOC103462087 LOC103462087 LOC103466577 LOC103466577 LOC103459060 LOC103459060 suclg1 suclg1 ppard ppard cs cs Rxra Rxra idh3g idh3g LOC103481996 LOC103481996 ENSPREP00000029837 ENSPREP00000029837 LOC103475424 LOC103475424 LOC103475425 LOC103475425 idh3b idh3b DLST DLST LOC103466147 LOC103466147 LOC103472118 LOC103472118 pdhx pdhx LOC103472117 LOC103472117 LACTB2 LACTB2 pdp1 pdp1 suclg2 suclg2 me2 me2 l2hgdh l2hgdh ENSPREP00000026406 ENSPREP00000026406 dlat dlat ACO2 ACO2 sdhd sdhd me1 me1 ogdh ogdh ENSPREP00000022378 ENSPREP00000022378 LOC103466019 LOC103466019 mpc2 mpc2 gstz1 gstz1 pdha1 pdha1 ENSPREP00000016750 ENSPREP00000016750 ldhb ldhb fh fh LOC103481842 LOC103481842 sdha sdha pdk3 pdk3 LOC103460857 LOC103460857 LOC103479501 LOC103479501 adhfe1 adhfe1 LOC103478929 LOC103478929 Mpc1 Mpc1 LOC103473658 LOC103473658 ENSPREP00000014189 ENSPREP00000014189 SDHB SDHB LOC103480192 LOC103480192 d2hgdh d2hgdh dld dld vdac1 vdac1 GLO1 GLO1 pdpr pdpr pdk1 pdk1 LOC103462181 LOC103462181 LOC103465156 LOC103465156 fahd1 fahd1 mblac2 mblac2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
haghHydroxyacylglutathione hydrolase. (309 aa)
HAGHLHydroxyacylglutathione hydrolase like. (290 aa)
LOC103460042Protein-serine/threonine kinase. (410 aa)
fam114a1Family with sequence similarity 114 member A1. (555 aa)
LOC103466626Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
idh3aIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (371 aa)
LOC103465809L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (355 aa)
LOC103462087Nicotinamide nucleotide transhydrogenase 2. (1014 aa)
LOC103466577Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (362 aa)
LOC103459060Dihydrolipoamide S-succinyltransferase. (433 aa)
suclg1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (337 aa)
ppardPeroxisome proliferator-activated receptor delta b. (401 aa)
csCitrate synthase; Belongs to the citrate synthase family. (469 aa)
RxraRetinoid X receptor, alpha a. (410 aa)
idh3gIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (389 aa)
LOC103481996Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (783 aa)
ENSPREP00000029837Uncharacterized protein. (88 aa)
LOC103475424Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
LOC103475425Uncharacterized protein. (609 aa)
idh3bIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (386 aa)
DLSTDihydrolipoamide S-succinyltransferase. (436 aa)
LOC103466147L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
LOC103472118Glutathione S-transferase rho; Belongs to the GST superfamily. (215 aa)
pdhxDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (493 aa)
LOC103472117Uncharacterized protein; Belongs to the GST superfamily. (226 aa)
LACTB2Lactamase beta 2. (318 aa)
pdp1Pyruvate dehyrogenase phosphatase catalytic subunit 1. (580 aa)
suclg2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (428 aa)
me2Malic enzyme. (582 aa)
l2hgdhL-2-hydroxyglutarate dehydrogenase. (447 aa)
ENSPREP00000026406Oxoglutarate dehydrogenase. (353 aa)
dlatAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (643 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (772 aa)
sdhdSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (166 aa)
me1Malic enzyme. (588 aa)
ogdhOxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). (1019 aa)
ENSPREP00000022378Si:ch211-15p9.2. (508 aa)
LOC103466019Putative pyruvate dehydrogenase phosphatase isoenzyme 2. (527 aa)
mpc2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (123 aa)
gstz1Glutathione S-transferase zeta 1; Belongs to the GST superfamily. (273 aa)
pdha1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (400 aa)
ENSPREP00000016750Succinate-CoA ligase, ADP-forming, beta subunit. (378 aa)
ldhbL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
fhFumarate hydratase. (499 aa)
LOC103481842Protein-serine/threonine kinase. (385 aa)
sdhaSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (663 aa)
pdk3Protein-serine/threonine kinase. (404 aa)
LOC103460857PNKD metallo-beta-lactamase domain containing. (360 aa)
LOC103479501Succinate dehydrogenase complex, subunit C, integral membrane protein. (153 aa)
adhfe1Alcohol dehydrogenase iron containing 1. (526 aa)
LOC103478929Si:ch73-71c20.5. (138 aa)
Mpc1Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (93 aa)
LOC103473658Nicotinamide nucleotide transhydrogenase. (1096 aa)
ENSPREP00000014189Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (202 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (339 aa)
LOC103480192Malic enzyme. (454 aa)
d2hgdhD-2-hydroxyglutarate dehydrogenase. (513 aa)
dldDihydrolipoyl dehydrogenase. (508 aa)
vdac1Voltage-dependent anion channel 1. (258 aa)
GLO1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (201 aa)
pdprPyruvate dehydrogenase phosphatase regulatory subunit. (892 aa)
pdk1Protein-serine/threonine kinase. (460 aa)
LOC103462181Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (455 aa)
LOC103465156Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (290 aa)
fahd1Fumarylacetoacetate hydrolase domain containing 1. (218 aa)
mblac2Metallo-beta-lactamase domain containing 2. (276 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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