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ENSPREP00000018529 ENSPREP00000018529 cpsf4 cpsf4 lsm11 lsm11 clp1 clp1 cstf2 cstf2 pabpn1 pabpn1 cstf1 cstf1 papolg papolg lsm10 lsm10 cpsf2 cpsf2 sympk sympk NCBP1 NCBP1 CPSF3 CPSF3 cpsf6 cpsf6 Pcf11 Pcf11 ENSPREP00000001871 ENSPREP00000001871 nudt21 nudt21 WDR33 WDR33 CPSF7 CPSF7 PABPN1L PABPN1L ncbp2 ncbp2 cpsf1 cpsf1 LOC103457156 LOC103457156 cstf3 cstf3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPREP00000018529FIP1 like 1b (S. cerevisiae). (435 aa)
cpsf4Cleavage and polyadenylation specific factor 4. (262 aa)
lsm11LSM11, U7 small nuclear RNA associated. (339 aa)
clp1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (441 aa)
cstf2Cleavage stimulation factor, 3' pre-RNA, subunit 2. (556 aa)
pabpn1Poly(A) binding protein, nuclear 1. (286 aa)
cstf1Cleavage stimulation factor, 3' pre-RNA, subunit 1. (431 aa)
papolgPoly(A) polymerase gamma. (847 aa)
lsm10LSM10, U7 small nuclear RNA associated. (131 aa)
cpsf2Cleavage and polyadenylation specificity factor subunit 2. (787 aa)
sympkSymplekin. (1220 aa)
NCBP1Nuclear cap binding protein subunit 1. (797 aa)
CPSF3Cleavage and polyadenylation specific factor 3. (653 aa)
cpsf6Cleavage and polyadenylation specific factor 6. (586 aa)
Pcf11CID domain-containing protein. (87 aa)
ENSPREP00000001871SLBP_RNA_bind domain-containing protein. (251 aa)
nudt21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (229 aa)
WDR33WD repeat domain 33. (893 aa)
CPSF7Cleavage and polyadenylation specific factor 7. (451 aa)
PABPN1LPoly(A) binding protein nuclear 1 like, cytoplasmic. (231 aa)
ncbp2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (194 aa)
cpsf1Cleavage and polyadenylation specific factor 1. (1471 aa)
LOC103457156Cleavage and polyadenylation specific factor 3. (627 aa)
cstf3Cleavage stimulation factor, 3' pre-RNA, subunit 3. (716 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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