STRINGSTRING
nelfe nelfe ENSPREP00000001027 ENSPREP00000001027 polr2i polr2i nelfa nelfa aff1 aff1 eaf2 eaf2 polr2c polr2c cdk7 cdk7 ctr9 ctr9 ELOB ELOB polr2l polr2l slc39a13 slc39a13 ENSPREP00000032704 ENSPREP00000032704 polr2d polr2d ncbp2 ncbp2 ercc3 ercc3 gtf2f2 gtf2f2 gtf2h3 gtf2h3 LOC103478624 LOC103478624 gtf2h4 gtf2h4 ccnt1 ccnt1 LOC103467918 LOC103467918 ercc2 ercc2 eaf1 eaf1 rtf1 rtf1 leo1 leo1 ssrp1 ssrp1 ccnk ccnk polr2f polr2f polr2g polr2g Ctdp1 Ctdp1 ccnt2 ccnt2 tcea1 tcea1 mnat1 mnat1 polr2j polr2j ENSPREP00000003308 ENSPREP00000003308 LOC103461004 LOC103461004 eloc eloc gtf2h1 gtf2h1 nelfb nelfb nelfcd nelfcd polr2a polr2a wdr61 wdr61 Tceanc Tceanc LOC103470674 LOC103470674 tceanc2 tceanc2 polr2b polr2b paf1 paf1 LOC103468942 LOC103468942 supt6h supt6h ell ell supt16h supt16h mllt1 mllt1 ENSPREP00000012814 ENSPREP00000012814 LOC103478445 LOC103478445 ENSPREP00000012074 ENSPREP00000012074 eloa eloa supt4h1 supt4h1 Cdk9 Cdk9 IWS1 IWS1 polr2h polr2h supt5h supt5h POLR2E POLR2E NCBP1 NCBP1 cdc73 cdc73 ccnq ccnq aff4 aff4 cinp cinp mllt3 mllt3 gtf2h5 gtf2h5 ccnh ccnh
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
nelfeNegative elongation factor complex member E. (325 aa)
ENSPREP00000001027Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (467 aa)
polr2iDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
nelfaNegative elongation factor complex member A. (547 aa)
aff1Uncharacterized protein. (1096 aa)
eaf2ELL associated factor 2. (255 aa)
polr2cPolymerase (RNA) II (DNA directed) polypeptide C. (273 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (387 aa)
ctr9CTR9 homolog, Paf1/RNA polymerase II complex component. (1154 aa)
ELOBElongin B. (119 aa)
polr2lPolymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
slc39a13Solute carrier family 39 member 13. (381 aa)
ENSPREP00000032704TFIIS N-terminal domain-containing protein. (269 aa)
polr2dPolymerase (RNA) II (DNA directed) polypeptide D. (104 aa)
ncbp2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (194 aa)
ercc3Excision repair cross-complementation group 3. (783 aa)
gtf2f2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (312 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (277 aa)
LOC103478624Si:dkey-12j5.1. (361 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (434 aa)
ccnt1Cyclin T1; Belongs to the cyclin family. (189 aa)
LOC103467918Transcription elongation factor A (SII), 2. (369 aa)
ercc2Excision repair cross-complementation group 2. (655 aa)
eaf1EAF domain-containing protein. (282 aa)
rtf1RTF1 homolog, Paf1/RNA polymerase II complex component. (663 aa)
leo1LEO1 homolog, Paf1/RNA polymerase II complex component. (631 aa)
ssrp1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (730 aa)
ccnkCyclin K; Belongs to the cyclin family. (541 aa)
polr2fPolymerase (RNA) II (DNA directed) polypeptide F. (98 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (172 aa)
Ctdp1FCP1 homology domain-containing protein. (271 aa)
ccnt2Cyclin T2; Belongs to the cyclin family. (687 aa)
tcea1Transcription elongation factor A (SII), 1. (320 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
polr2jPolymerase (RNA) II (DNA directed) polypeptide J. (117 aa)
ENSPREP00000003308Uncharacterized protein. (202 aa)
LOC103461004General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (267 aa)
elocElongin C paralog a; Belongs to the SKP1 family. (112 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (550 aa)
nelfbNegative elongation factor complex member B. (587 aa)
nelfcdNegative elongation factor complex member C/D. (578 aa)
polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1966 aa)
wdr61WD repeat domain 61. (305 aa)
TceancUncharacterized protein. (355 aa)
LOC103470674General transcription factor IIH subunit. (420 aa)
tceanc2Uncharacterized protein. (206 aa)
polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
paf1PAF1 homolog, Paf1/RNA polymerase II complex component. (531 aa)
LOC103468942Elongin B. (117 aa)
supt6hTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1825 aa)
ellElongation factor RNA polymerase II. (611 aa)
supt16hSPT16 homolog, facilitates chromatin remodeling subunit. (1077 aa)
mllt1MLLT1 super elongation complex subunit a. (586 aa)
ENSPREP00000012814Uncharacterized protein. (74 aa)
LOC103478445Transcription elongation factor A (SII), 3. (562 aa)
ENSPREP00000012074CYCLIN domain-containing protein; Belongs to the cyclin family. (177 aa)
eloaElongin A. (681 aa)
supt4h1SPT4 homolog, DSIF elongation factor subunit. (174 aa)
Cdk9Cyclin-dependent kinase 9 (CDC2-related kinase). (552 aa)
IWS1Interacts with SUPT6H, CTD assembly factor 1. (766 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
supt5hTranscription elongation factor SPT5. (1059 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
NCBP1Nuclear cap binding protein subunit 1. (797 aa)
cdc73Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). (576 aa)
ccnqCyclin Q; Belongs to the cyclin family. (252 aa)
aff4AF4/FMR2 family, member 4. (1106 aa)
cinpCyclin-dependent kinase 2 interacting protein. (209 aa)
mllt3MLLT3 super elongation complex subunit. (507 aa)
gtf2h5General transcription factor IIH, polypeptide 5. (71 aa)
ccnhCyclin H; Belongs to the cyclin family. (319 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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