31 items (Poecilia reticulata) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

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Your Input:
	ENSPREP00000001027	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (467 aa)
	cdk7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (387 aa)
	polr2c	Polymerase (RNA) II (DNA directed) polypeptide C. (273 aa)
	polr2i	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
	ccnh	Cyclin H; Belongs to the cyclin family. (319 aa)
	gtf2h5	General transcription factor IIH, polypeptide 5. (71 aa)
	POLR2E	RNA polymerase II subunit E. (210 aa)
	supt5h	Transcription elongation factor SPT5. (1059 aa)
	polr2h	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	ENSPREP00000012814	Uncharacterized protein. (74 aa)
	rngtt	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (604 aa)
	polr2b	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
	LOC103470674	General transcription factor IIH subunit. (420 aa)
	LOC103473138	Dual specificity phosphatase 11 (RNA/RNP complex 1-interacting). (386 aa)
	rnmt	mRNA cap guanine-N7 methyltransferase. (386 aa)
	polr2a	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1966 aa)
	gtf2h1	General transcription factor IIH, polypeptide 1. (550 aa)
	LOC103461004	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (267 aa)
	polr2j	Polymerase (RNA) II (DNA directed) polypeptide J. (117 aa)
	mnat1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
	ENSPREP00000023914	TYR_PHOSPHATASE_2 domain-containing protein. (174 aa)
	polr2g	Polymerase (RNA) II (DNA directed) polypeptide G-like. (172 aa)
	polr2f	Polymerase (RNA) II (DNA directed) polypeptide F. (98 aa)
	ercc2	Excision repair cross-complementation group 2. (655 aa)
	gtf2h4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (434 aa)
	gtf2h3	General transcription factor IIH, polypeptide 3. (277 aa)
	gtf2f2	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (312 aa)
	ercc3	Excision repair cross-complementation group 3. (783 aa)
	polr2d	Polymerase (RNA) II (DNA directed) polypeptide D. (104 aa)
	polr2l	Polymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
	spag7	Sperm-associated antigen 7 homolog. (236 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000001027	ENSPREP00000012814	ENSPREP00000001027	ENSPREP00000012814	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Uncharacterized protein.	0.966
ENSPREP00000001027	ENSPREP00000023914	ENSPREP00000001027	ENSPREP00000023914	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	TYR_PHOSPHATASE_2 domain-containing protein.	0.609
ENSPREP00000001027	LOC103461004	ENSPREP00000001027	ENSPREP00000020577	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.978
ENSPREP00000001027	LOC103470674	ENSPREP00000001027	ENSPREP00000017962	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	General transcription factor IIH subunit.	0.973
ENSPREP00000001027	LOC103473138	ENSPREP00000001027	ENSPREP00000018692	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Dual specificity phosphatase 11 (RNA/RNP complex 1-interacting).	0.609
ENSPREP00000001027	POLR2E	ENSPREP00000001027	ENSPREP00000009571	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	RNA polymerase II subunit E.	0.992
ENSPREP00000001027	ccnh	ENSPREP00000001027	ENSPREP00000006353	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Cyclin H; Belongs to the cyclin family.	0.924
ENSPREP00000001027	cdk7	ENSPREP00000001027	ENSPREP00000003727	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily.	0.798
ENSPREP00000001027	ercc2	ENSPREP00000001027	ENSPREP00000028527	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Excision repair cross-complementation group 2.	0.966
ENSPREP00000001027	ercc3	ENSPREP00000001027	ENSPREP00000030919	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Excision repair cross-complementation group 3.	0.975
ENSPREP00000001027	gtf2f2	ENSPREP00000001027	ENSPREP00000030834	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.978
ENSPREP00000001027	gtf2h1	ENSPREP00000001027	ENSPREP00000019946	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	General transcription factor IIH, polypeptide 1.	0.975
ENSPREP00000001027	gtf2h3	ENSPREP00000001027	ENSPREP00000030691	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	General transcription factor IIH, polypeptide 3.	0.975
ENSPREP00000001027	gtf2h4	ENSPREP00000001027	ENSPREP00000029112	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.981
ENSPREP00000001027	gtf2h5	ENSPREP00000001027	ENSPREP00000006463	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	General transcription factor IIH, polypeptide 5.	0.933
ENSPREP00000001027	mnat1	ENSPREP00000001027	ENSPREP00000022935	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.	0.969
ENSPREP00000001027	polr2a	ENSPREP00000001027	ENSPREP00000019508	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.976
ENSPREP00000001027	polr2b	ENSPREP00000001027	ENSPREP00000016486	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.997
ENSPREP00000001027	polr2c	ENSPREP00000001027	ENSPREP00000004397	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Polymerase (RNA) II (DNA directed) polypeptide C.	0.994
ENSPREP00000001027	polr2d	ENSPREP00000001027	ENSPREP00000032271	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	Polymerase (RNA) II (DNA directed) polypeptide D.	0.985