(44 nodes) Insulin receptor recycling network (Poecilia reticulata)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	ENSPREP00000028621	Uncharacterized protein. (588 aa)
	LOC103467444	ATPase H+ transporting accessory protein 1 like b. (341 aa)
	atp6v1a	ATPase H+ transporting V1 subunit A. (617 aa)
	LOC103481105	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (153 aa)
	LOC103476533	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (472 aa)
	LOC103462946	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
	LOC103476384	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (79 aa)
	LOC103460439	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (95 aa)
	ENSPREP00000025003	Uncharacterized protein. (394 aa)
	atp6v0b	ATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (211 aa)
	atp6v1c1	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (283 aa)
	atp6v1h	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (451 aa)
	LOC103469107	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (154 aa)
	insr	Insulin receptor a. (1178 aa)
	ATP6V1B2	ATPase H+ transporting V1 subunit B2. (563 aa)
	ptprf	Protein tyrosine phosphatase receptor type Fb. (1797 aa)
	LOC103474212	Lens intrinsic membrane protein 2.3. (180 aa)
	cnst	Consortin_C domain-containing protein. (776 aa)
	LOC103473697	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (846 aa)
	nrdc	Nardilysin a (N-arginine dibasic convertase); Belongs to the peptidase M16 family. (1166 aa)
	LOC103469401	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (826 aa)
	atp6v1d	ATPase H+ transporting V1 subunit D. (248 aa)
	LOC103472369	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (397 aa)
	atp6v1f	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
	NRDC	Nardilysin b (N-arginine dibasic convertase); Belongs to the peptidase M16 family. (570 aa)
	ENSPREP00000008079	Uncharacterized protein. (211 aa)
	LOC103458675	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (351 aa)
	LOC103482186	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (840 aa)
	ide	Insulin-degrading enzyme; Belongs to the peptidase M16 family. (1064 aa)
	LOC103471301	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (760 aa)
	atp6ap1	ATPase H+ transporting accessory protein 1a. (489 aa)
	LOC103467754	Tyrosine-protein phosphatase non-receptor type. (432 aa)
	LOC103459166	ATPase H+ transporting V1 subunit E1b. (196 aa)
	LOC103464332	ATPase H+ transporting accessory protein 1 like a. (314 aa)
	atp6v0a2	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (846 aa)
	LOC103470048	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
	LOC103467860	ATPase H+ transporting accessory protein 1b. (446 aa)
	ENSPREP00000030771	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (65 aa)
	atp6v1e1	ATPase H+ transporting V1 subunit E1a. (229 aa)
	LOC103475419	Uncharacterized protein. (617 aa)
	LOC108166607	ATPase H+ transporting V0 subunit e1. (80 aa)
	ENSPREP00000028643	Uncharacterized protein. (199 aa)
	ENSPREP00000028631	Fibronectin type-III domain-containing protein. (112 aa)
	LOC103457779	Consortin, connexin sorting protein b. (381 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP6V1B2	LOC103457779	ENSPREP00000018747	ENSPREP00000028359	ATPase H+ transporting V1 subunit B2.	Consortin, connexin sorting protein b.	0.967
ATP6V1B2	LOC103458675	ENSPREP00000018747	ENSPREP00000006395	ATPase H+ transporting V1 subunit B2.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.943
ATP6V1B2	LOC103459166	ENSPREP00000018747	ENSPREP00000033797	ATPase H+ transporting V1 subunit B2.	ATPase H+ transporting V1 subunit E1b.	0.991
ATP6V1B2	LOC103460439	ENSPREP00000018747	ENSPREP00000025327	ATPase H+ transporting V1 subunit B2.	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.988
ATP6V1B2	LOC103462946	ENSPREP00000018747	ENSPREP00000027176	ATPase H+ transporting V1 subunit B2.	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.999
ATP6V1B2	LOC103464332	ENSPREP00000018747	ENSPREP00000033713	ATPase H+ transporting V1 subunit B2.	ATPase H+ transporting accessory protein 1 like a.	0.841
ATP6V1B2	LOC103467444	ENSPREP00000018747	ENSPREP00000028340	ATPase H+ transporting V1 subunit B2.	ATPase H+ transporting accessory protein 1 like b.	0.841
ATP6V1B2	LOC103467860	ENSPREP00000018747	ENSPREP00000030801	ATPase H+ transporting V1 subunit B2.	ATPase H+ transporting accessory protein 1b.	0.949
ATP6V1B2	LOC103469107	ENSPREP00000018747	ENSPREP00000022457	ATPase H+ transporting V1 subunit B2.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.982
ATP6V1B2	LOC103469401	ENSPREP00000018747	ENSPREP00000014486	ATPase H+ transporting V1 subunit B2.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.968
ATP6V1B2	LOC103470048	ENSPREP00000018747	ENSPREP00000031179	ATPase H+ transporting V1 subunit B2.	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.939
ATP6V1B2	LOC103471301	ENSPREP00000018747	ENSPREP00000003416	ATPase H+ transporting V1 subunit B2.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.926
ATP6V1B2	LOC103472369	ENSPREP00000018747	ENSPREP00000010223	ATPase H+ transporting V1 subunit B2.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.994
ATP6V1B2	LOC103473697	ENSPREP00000018747	ENSPREP00000015994	ATPase H+ transporting V1 subunit B2.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.926
ATP6V1B2	LOC103474212	ENSPREP00000018747	ENSPREP00000016886	ATPase H+ transporting V1 subunit B2.	Lens intrinsic membrane protein 2.3.	0.967
ATP6V1B2	LOC103475419	ENSPREP00000018747	ENSPREP00000030257	ATPase H+ transporting V1 subunit B2.	Uncharacterized protein.	0.998
ATP6V1B2	LOC103476533	ENSPREP00000018747	ENSPREP00000027429	ATPase H+ transporting V1 subunit B2.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.900
ATP6V1B2	LOC103481105	ENSPREP00000018747	ENSPREP00000027946	ATPase H+ transporting V1 subunit B2.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.982
ATP6V1B2	LOC103482186	ENSPREP00000018747	ENSPREP00000005132	ATPase H+ transporting V1 subunit B2.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.968
ATP6V1B2	LOC108166607	ENSPREP00000018747	ENSPREP00000028911	ATPase H+ transporting V1 subunit B2.	ATPase H+ transporting V0 subunit e1.	0.939