(6 nodes) TRAF3-dependent IRF activation pathway network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103468460	E1A binding protein p300 b. (2737 aa)
	irf7	Interferon regulatory factor 7. (472 aa)
	LOC103482005	E1A binding protein p300 a. (2743 aa)
	LOC103481249	Interferon regulatory factor 3. (465 aa)
	LOC103464091	CREB binding protein a. (2371 aa)
	crebbp	CREB binding protein b. (2452 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103464091	LOC103468460	ENSPREP00000000408	ENSPREP00000026558	CREB binding protein a.	E1A binding protein p300 b.	0.928
LOC103464091	LOC103481249	ENSPREP00000000408	ENSPREP00000032515	CREB binding protein a.	Interferon regulatory factor 3.	0.968
LOC103464091	LOC103482005	ENSPREP00000000408	ENSPREP00000030842	CREB binding protein a.	E1A binding protein p300 a.	0.928
LOC103464091	irf7	ENSPREP00000000408	ENSPREP00000028492	CREB binding protein a.	Interferon regulatory factor 7.	0.743
LOC103468460	LOC103464091	ENSPREP00000026558	ENSPREP00000000408	E1A binding protein p300 b.	CREB binding protein a.	0.928
LOC103468460	LOC103481249	ENSPREP00000026558	ENSPREP00000032515	E1A binding protein p300 b.	Interferon regulatory factor 3.	0.934
LOC103468460	LOC103482005	ENSPREP00000026558	ENSPREP00000030842	E1A binding protein p300 b.	E1A binding protein p300 a.	0.902
LOC103468460	crebbp	ENSPREP00000026558	ENSPREP00000011232	E1A binding protein p300 b.	CREB binding protein b.	0.992
LOC103468460	irf7	ENSPREP00000026558	ENSPREP00000028492	E1A binding protein p300 b.	Interferon regulatory factor 7.	0.715
LOC103481249	LOC103464091	ENSPREP00000032515	ENSPREP00000000408	Interferon regulatory factor 3.	CREB binding protein a.	0.968
LOC103481249	LOC103468460	ENSPREP00000032515	ENSPREP00000026558	Interferon regulatory factor 3.	E1A binding protein p300 b.	0.934
LOC103481249	LOC103482005	ENSPREP00000032515	ENSPREP00000030842	Interferon regulatory factor 3.	E1A binding protein p300 a.	0.934
LOC103481249	crebbp	ENSPREP00000032515	ENSPREP00000011232	Interferon regulatory factor 3.	CREB binding protein b.	0.968
LOC103481249	irf7	ENSPREP00000032515	ENSPREP00000028492	Interferon regulatory factor 3.	Interferon regulatory factor 7.	0.984
LOC103482005	LOC103464091	ENSPREP00000030842	ENSPREP00000000408	E1A binding protein p300 a.	CREB binding protein a.	0.928
LOC103482005	LOC103468460	ENSPREP00000030842	ENSPREP00000026558	E1A binding protein p300 a.	E1A binding protein p300 b.	0.902
LOC103482005	LOC103481249	ENSPREP00000030842	ENSPREP00000032515	E1A binding protein p300 a.	Interferon regulatory factor 3.	0.934
LOC103482005	crebbp	ENSPREP00000030842	ENSPREP00000011232	E1A binding protein p300 a.	CREB binding protein b.	0.992
LOC103482005	irf7	ENSPREP00000030842	ENSPREP00000028492	E1A binding protein p300 a.	Interferon regulatory factor 7.	0.715
crebbp	LOC103468460	ENSPREP00000011232	ENSPREP00000026558	CREB binding protein b.	E1A binding protein p300 b.	0.992