(8 nodes) (2010) Dengue viral infections. network (Poecilia reticulata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	f2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (617 aa)
	GOT1	Aspartate aminotransferase. (463 aa)
	got1	Aspartate aminotransferase. (398 aa)
	IL18	Uncharacterized protein. (218 aa)
	serpinc1	Serpin peptidase inhibitor, clade C (antithrombin), member 1; Belongs to the serpin family. (455 aa)
	il10	Interleukin 10. (229 aa)
	ENSPREP00000009963	Interleukin; Belongs to the IL-15/IL-21 family. (96 aa)
	got2	Aspartate aminotransferase. (393 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000009963	IL18	ENSPREP00000009963	ENSPREP00000023832	Interleukin; Belongs to the IL-15/IL-21 family.	Uncharacterized protein.	0.630
ENSPREP00000009963	il10	ENSPREP00000009963	ENSPREP00000005577	Interleukin; Belongs to the IL-15/IL-21 family.	Interleukin 10.	0.660
GOT1	f2	ENSPREP00000031324	ENSPREP00000016717	Aspartate aminotransferase.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.534
GOT1	got2	ENSPREP00000031324	ENSPREP00000021995	Aspartate aminotransferase.	Aspartate aminotransferase.	0.967
IL18	ENSPREP00000009963	ENSPREP00000023832	ENSPREP00000009963	Uncharacterized protein.	Interleukin; Belongs to the IL-15/IL-21 family.	0.630
IL18	f2	ENSPREP00000023832	ENSPREP00000016717	Uncharacterized protein.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.406
IL18	il10	ENSPREP00000023832	ENSPREP00000005577	Uncharacterized protein.	Interleukin 10.	0.806
f2	GOT1	ENSPREP00000016717	ENSPREP00000031324	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Aspartate aminotransferase.	0.534
f2	IL18	ENSPREP00000016717	ENSPREP00000023832	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.406
f2	got1	ENSPREP00000016717	ENSPREP00000029105	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Aspartate aminotransferase.	0.534
f2	got2	ENSPREP00000016717	ENSPREP00000021995	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Aspartate aminotransferase.	0.608
f2	serpinc1	ENSPREP00000016717	ENSPREP00000001582	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Serpin peptidase inhibitor, clade C (antithrombin), member 1; Belongs to the serpin family.	0.999
got1	f2	ENSPREP00000029105	ENSPREP00000016717	Aspartate aminotransferase.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.534
got1	got2	ENSPREP00000029105	ENSPREP00000021995	Aspartate aminotransferase.	Aspartate aminotransferase.	0.695
got2	GOT1	ENSPREP00000021995	ENSPREP00000031324	Aspartate aminotransferase.	Aspartate aminotransferase.	0.967
got2	f2	ENSPREP00000021995	ENSPREP00000016717	Aspartate aminotransferase.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.608
got2	got1	ENSPREP00000021995	ENSPREP00000029105	Aspartate aminotransferase.	Aspartate aminotransferase.	0.695
got2	il10	ENSPREP00000021995	ENSPREP00000005577	Aspartate aminotransferase.	Interleukin 10.	0.549
il10	ENSPREP00000009963	ENSPREP00000005577	ENSPREP00000009963	Interleukin 10.	Interleukin; Belongs to the IL-15/IL-21 family.	0.660
il10	IL18	ENSPREP00000005577	ENSPREP00000023832	Interleukin 10.	Uncharacterized protein.	0.806