(33 nodes) Galactose metabolism network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103481270	Si:ch73-12o23.1; Belongs to the glycosyl hydrolase 31 family. (972 aa)
	galk1	Galactokinase 1. (393 aa)
	galt	Galactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. (364 aa)
	glb1	Beta-galactosidase. (652 aa)
	gaa	Glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II); Belongs to the glycosyl hydrolase 31 family. (932 aa)
	pgm2	Phosphoglucomutase 2. (611 aa)
	Ganc	Uncharacterized protein; Belongs to the glycosyl hydrolase 31 family. (371 aa)
	ENSPREP00000013735	Phosphotransferase. (233 aa)
	LOC103461671	Galactosidase, beta 1-like; Belongs to the glycosyl hydrolase 35 family. (634 aa)
	pfkl	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
	g6pc3	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (339 aa)
	gck	Phosphotransferase. (433 aa)
	LOC103457016	Uncharacterized protein. (337 aa)
	LOC103457015	Uncharacterized protein. (346 aa)
	LOC103459462	Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 2. (316 aa)
	b4galt1	DP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1, like. (367 aa)
	g6pc	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (348 aa)
	LOC103481694	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (351 aa)
	gla	Alpha-galactosidase. (419 aa)
	LOC103462844	Hexokinase domain containing 1. (907 aa)
	LOC103462845	Phosphotransferase. (264 aa)
	LOC103456521	Uncharacterized protein. (348 aa)
	LOC103465370	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (761 aa)
	ENSPREP00000024761	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2. (321 aa)
	si	Uncharacterized protein. (1818 aa)
	ENSPREP00000026193	Phosphotransferase. (242 aa)
	pfkp	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (789 aa)
	LOC103457329	Uncharacterized protein. (337 aa)
	LOC103469870	UTP--glucose-1-phosphate uridylyltransferase. (492 aa)
	pgm1	Phosphoglucomutase 1; Belongs to the phosphohexose mutase family. (561 aa)
	LOC103476492	UTP--glucose-1-phosphate uridylyltransferase. (508 aa)
	HK1	Hexokinase 1. (923 aa)
	LOC103467300	6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily. (754 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000013735	ENSPREP00000026193	ENSPREP00000013735	ENSPREP00000026193	Phosphotransferase.	Phosphotransferase.	0.994
ENSPREP00000013735	Ganc	ENSPREP00000013735	ENSPREP00000012227	Phosphotransferase.	Uncharacterized protein; Belongs to the glycosyl hydrolase 31 family.	0.650
ENSPREP00000013735	HK1	ENSPREP00000013735	ENSPREP00000031688	Phosphotransferase.	Hexokinase 1.	0.900
ENSPREP00000013735	LOC103459462	ENSPREP00000013735	ENSPREP00000016213	Phosphotransferase.	Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 2.	0.814
ENSPREP00000013735	LOC103461671	ENSPREP00000013735	ENSPREP00000013740	Phosphotransferase.	Galactosidase, beta 1-like; Belongs to the glycosyl hydrolase 35 family.	0.900
ENSPREP00000013735	LOC103462844	ENSPREP00000013735	ENSPREP00000023097	Phosphotransferase.	Hexokinase domain containing 1.	0.901
ENSPREP00000013735	LOC103462845	ENSPREP00000013735	ENSPREP00000023282	Phosphotransferase.	Phosphotransferase.	0.991
ENSPREP00000013735	LOC103465370	ENSPREP00000013735	ENSPREP00000024264	Phosphotransferase.	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	0.830
ENSPREP00000013735	LOC103467300	ENSPREP00000013735	ENSPREP00000033359	Phosphotransferase.	6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.	0.772
ENSPREP00000013735	LOC103481270	ENSPREP00000013735	ENSPREP00000000180	Phosphotransferase.	Si:ch73-12o23.1; Belongs to the glycosyl hydrolase 31 family.	0.689
ENSPREP00000013735	LOC103481694	ENSPREP00000013735	ENSPREP00000017031	Phosphotransferase.	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family.	0.912
ENSPREP00000013735	g6pc	ENSPREP00000013735	ENSPREP00000016960	Phosphotransferase.	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family.	0.912
ENSPREP00000013735	g6pc3	ENSPREP00000013735	ENSPREP00000015190	Phosphotransferase.	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family.	0.914
ENSPREP00000013735	gaa	ENSPREP00000013735	ENSPREP00000009169	Phosphotransferase.	Glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II); Belongs to the glycosyl hydrolase 31 family.	0.689
ENSPREP00000013735	glb1	ENSPREP00000013735	ENSPREP00000007943	Phosphotransferase.	Beta-galactosidase.	0.900
ENSPREP00000013735	pfkl	ENSPREP00000013735	ENSPREP00000014543	Phosphotransferase.	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	0.830
ENSPREP00000013735	pfkp	ENSPREP00000013735	ENSPREP00000027841	Phosphotransferase.	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	0.829
ENSPREP00000013735	pgm1	ENSPREP00000013735	ENSPREP00000030463	Phosphotransferase.	Phosphoglucomutase 1; Belongs to the phosphohexose mutase family.	0.936
ENSPREP00000013735	pgm2	ENSPREP00000013735	ENSPREP00000009877	Phosphotransferase.	Phosphoglucomutase 2.	0.935
ENSPREP00000013735	si	ENSPREP00000013735	ENSPREP00000025479	Phosphotransferase.	Uncharacterized protein.	0.689